You are viewing an incomplete version of our website. Please click to reload the website as full version.

Exosome Component 10 Proteins (EXOSC10)

Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. Additionally we are shipping Exosome Component 10 Antibodies (40) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EXOSC10 5394 Q01780
EXOSC10 50912 P56960
Rat EXOSC10 EXOSC10 313707  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Exosome Component 10 Proteins at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Sf-9 cells Mouse Biotin   1 mg Log in to see 3 to 4 Days
$3,899.50
Details
HOST_Sf-9 cells Human Un-conjugated   5 μg Log in to see 6 to 11 Days
$142.86
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

EXOSC10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine) ,
,

More Proteins for Exosome Component 10 (EXOSC10) Interaction Partners

Human Exosome Component 10 (EXOSC10) interaction partners

  1. Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination

  2. EXOSC10 can be modified by SUMOylation and identifies a physiological stress where this regulation is prevalent both in vitro and in vivo.

  3. Results show that DGCR8 (show DGCR8 Proteins) forms an alternative complex with the RRP6-containing form of the exosome, acts as an adaptor to recruit the exosome to target structured RNAs, and the DGCR8 (show DGCR8 Proteins)/hRRP6 complex controls the stability of human telomerase RNA.

  4. Microprocessor orchestrates the recruitment of termination factors Setx (show SETX Proteins) and Xrn2 (show XRN2 Proteins), and the 3'-5' exoribonuclease, Rrp6, to initiate RNAPII pausing and premature termination at the HIV-1 promoter through cleavage of the stem-loop RNA, TAR (show RBM8A Proteins).

  5. Systemic sclerosis patients with anti-PM-Scl antibody are younger and significantly more often have limited cutaneous involvement, skeletal muscle disease, pulmonary fibrosis and calcinosis.

  6. Saccharomyces cerevisiae Rrp6, and determined the X-ray structure of a human construct containing the exoribonuclease and HRDC domains that retains catalytic activity

  7. cloning of a more complete cDNA for PM/Scl-75 (show EXOSC9 Proteins) encoded 84 additional amino acids at its N terminus and only this longer polypeptide is able to associate with the exosome complex.

  8. Although not required for exosome stability, PM/Scl-100 and PM/Scl-75 (show EXOSC9 Proteins) are involved in mRNA degradation.

  9. Anti-PM/Scl antibodies are common in distinct SSc (show CYP11A1 Proteins) subsets and are associated with several clinical symptoms

  10. PM-Scl-75 (show EXOSC9 Proteins) is the main autoantigen in patients with the polymyositis/scleroderma overlap syndrome.

Exosome Component 10 (EXOSC10) Protein Profile

Protein Summary

Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3'-5' exonuclease activity (By similarity). EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA (By similarity).

Gene names and symbols associated with Exosome Component 10 Proteins (EXOSC10)

  • exosome component 10 (exosc10)
  • exosome component 10 (EXOSC10)
  • exosome component 10 (EHI_021400)
  • exosome component 10 (BBOV_IV002650)
  • exosome component 10 (CpipJ_CPIJ003896)
  • exosome component 10 (CMU_031760)
  • 3'-5' exonuclease (exosc10)
  • exosome component 10 (Tsp_05247)
  • Exosome component 10 (exosx)
  • exosome component 10 (Exosc10)
  • 21.m02990 protein
  • 201.t00018 protein
  • DDBDRAFT_0203581 protein
  • DDBDRAFT_0233752 protein
  • DDB_0203581 protein
  • DDB_0233752 protein
  • EXOSC10 protein
  • p2 protein
  • p3 protein
  • p4 protein
  • PM-Scl protein
  • PM/Scl-100 protein
  • PMSCL protein
  • PMSCL2 protein
  • RRP6 protein
  • Rrp6p protein
  • zgc:55695 protein

Protein level used designations for Exosome Component 10 Proteins (EXOSC10)

exosome component 10 , Exosome component 10 , P100 polymyositis-scleroderma overlap syndrome-associated autoantigen , autoantigen PM-SCL , autoantigen PM/Scl 2 , polymyositis/scleroderma autoantigen 100 kDa , polymyositis/scleroderma autoantigen 2 (100kD) , polymyositis/scleroderma autoantigen 2, 100kDa , autoantigen PM/Scl 2 homolog , polymyositis/scleroderma autoantigen 2 homolog

GENE ID SPECIES
394064 Danio rerio
407941 Xenopus (Silurana) tropicalis
419454 Gallus gallus
457944 Pan troglodytes
478233 Canis lupus familiaris
3405059 Entamoeba histolytica HM-1:IMSS
5477649 Babesia bovis T2Bo
6035353 Culex quinquefasciatus
6997478 Cryptosporidium muris RN66
8618039 Dictyostelium discoideum AX4
10913037 Trichinella spiralis
100014127 Monodelphis domestica
100056644 Equus caballus
100195333 Salmo salar
100355915 Oryctolagus cuniculus
100405990 Callithrix jacchus
100467172 Ailuropoda melanoleuca
100511264 Sus scrofa
100547497 Meleagris gallopavo
100593954 Nomascus leucogenys
431865 Xenopus laevis
5394 Homo sapiens
535340 Bos taurus
50912 Mus musculus
313707 Rattus norvegicus
Selected quality suppliers for Exosome Component 10 Proteins (EXOSC10)
Did you look for something else?