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Exosome Component 2 (EXOSC2) ELISA Kits

Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. Additionally we are shipping Exosome Component 2 Antibodies (38) and Exosome Component 2 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EXOSC2 23404 Q13868
Anti-Mouse EXOSC2 EXOSC2 227715 Q8VBV3
Anti-Rat EXOSC2 EXOSC2 366017  
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Top Exosome Component 2 ELISA Kits at antibodies-online.com

Showing 1 out of 4 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.061 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details

More ELISA Kits for Exosome Component 2 Interaction Partners

Human Exosome Component 2 (EXOSC2) interaction partners

  1. Knock-down of hRrp41p (show EXOSC4 ELISA Kits) or hRrp4p but not PM/Scl-100 or PM/Scl-75 (show EXOSC9 ELISA Kits) leads to codepletion of other subunits.

  2. Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase (show PNPT1 ELISA Kits)-like ring.

Exosome Component 2 (EXOSC2) Antigen Profile

Antigen Summary

Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7.

Gene names and symbols associated with Exosome Component 2 (EXOSC2) ELISA Kits

  • exosome component 2 (EXOSC2) antibody
  • exosome component 2 (exosc2) antibody
  • exosome component 2 (Bm1_33895) antibody
  • exosome component 2 (PTRG_00114) antibody
  • exosome component 2 (Exosc2) antibody
  • exosc2 antibody
  • fa97b01 antibody
  • hRrp4p antibody
  • MGC97533 antibody
  • p7 antibody
  • Rrp4 antibody
  • Rrp4p antibody
  • wu:fa97b01 antibody
  • zgc:110117 antibody

Protein level used designations for Exosome Component 2 (EXOSC2) ELISA Kits

exosome component 2 , exosome complex component RRP4 , exosome complex exonuclease RRP4 , homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4) , homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease , ribosomal RNA-processing protein 4 , homolog of Yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease , homolog of Yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exorib

GENE ID SPECIES
464801 Pan troglodytes
595050 Xenopus (Silurana) tropicalis
715960 Macaca mulatta
6101667 Brugia malayi
6340437 Pyrenophora tritici-repentis Pt-1C-BFP
23404 Homo sapiens
608606 Canis lupus familiaris
615712 Bos taurus
227715 Mus musculus
366017 Rattus norvegicus
550234 Danio rerio
444032 Xenopus laevis
417182 Gallus gallus
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