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Exosome Component 3 Proteins (EXOSC3)

EXOSC3 encodes a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Additionally we are shipping Exosome Component 3 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EXOSC3 51010 Q9NQT5
EXOSC3 66362 Q7TQK4
Rat EXOSC3 EXOSC3 313243  
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Top Exosome Component 3 Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$2,610.67
Details
Yeast Schizosaccharomyces pombe His tag   1 mg Log in to see 56 to 66 Days
$2,610.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,715.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

EXOSC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Exosome Component 3 (EXOSC3) Interaction Partners

Human Exosome Component 3 (EXOSC3) interaction partners

  1. EXOSC3 mutations were linked to complicated hereditary spastic paraplegia.

  2. study identified new nonsense and missense mutations in the EXOSC3 gene and showed mutations in this gene are exclusively found in pontocerebellar hypoplasia type 1 patients; there are evident genotype-phenotype correlations in EXOSC3-mediated PCH reflected in clinical outcome, age of death and pons hypoplasia

  3. The same mutation c.92G-->C, p.G31A in EXOSC3 was found in three unrelated Czech Roma patients with Pontocerebellar hypoplasia type 1

  4. The present study indicates that EXOSC3 mutations can underlie clinical phenotype not classifiable as pontocerebellar hypoplasia type 1.

  5. We identified a homozygous mutation [c.395A > C/p.D132A] in EXOSC3 in four patients with muscle hypotonia, developmental delay, spinal anterior horn involvement, and prolonged survival, consistent with the "mild PCH1 (show VRK1 Proteins) phenotype".

  6. Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase (show PNPT1 Proteins)-like ring.

Mouse (Murine) Exosome Component 3 (EXOSC3) interaction partners

  1. EXOSC3 mutations account for 30%-40% of patients with PCH1 (show VRK1 Proteins) with variability in survival and clinical severity that is correlated with the genotype.

Exosome Component 3 (EXOSC3) Protein Profile

Protein Summary

This gene encodes a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with Exosome Component 3 Proteins (EXOSC3)

  • exosome component 3 (EXOSC3)
  • exosome component 3 (exosc3)
  • exosome component 3 (Exosc3)
  • 2310005D06Rik protein
  • AI593501 protein
  • bA3J10.7 protein
  • hRrp-40 protein
  • im:7140537 protein
  • p10 protein
  • PCH1B protein
  • RP11-3J10.8 protein
  • Rrp40 protein
  • Rrp40p protein
  • zgc:112345 protein

Protein level used designations for Exosome Component 3 Proteins (EXOSC3)

exosome complex exonuclease RRP40 , exosome complex component RRP40 , exosome component 3 , ribosomal RNA-processing protein 40

GENE ID SPECIES
423626 Gallus gallus
465105 Pan troglodytes
716347 Macaca mulatta
100152421 Sus scrofa
734370 Xenopus laevis
51010 Homo sapiens
481616 Canis lupus familiaris
533245 Bos taurus
66362 Mus musculus
313243 Rattus norvegicus
565000 Danio rerio
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