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Exosome Component 5 Proteins (EXOSC5)

Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. Additionally we are shipping EXOSC5 Antibodies (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EXOSC5 56915 Q9NQT4
EXOSC5 27998 Q9CRA8
Rat EXOSC5 EXOSC5 308441  
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Top EXOSC5 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$2,557.50
Details
Yeast Schizosaccharomyces pombe His tag   1 mg Log in to see 56 to 66 Days
$2,566.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

EXOSC5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced EXOSC5 Proteins

  1. Human EXOSC5 Protein expressed in Escherichia coli (E. coli) - ABIN1098228 : Basu, Meng, Keim, Grinstein, Pefanis, Eccleston, Zhang, Myers, Wasserman, Wesemann, Januszyk, Gregory, Deng, Lima, Alt: The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. in Cell 2011 (PubMed)
    Show all 2 references for ABIN1098228

More Proteins for Exosome Component 5 (EXOSC5) Interaction Partners

Human Exosome Component 5 (EXOSC5) interaction partners

  1. Further, subcellular co-localization assay showed that the two proteins could co-localize in the cytoplasm of K562 cells, but WT1 (show WT1 Proteins)/CML28 complexes were not detected by using immunoprecipitation.

  2. Results suggest that Rrp46 forms a homodimer separately from exosome complexes and, depending on species, is a structural component of the machinery that cleaves DNA during apoptosis.

  3. association of hCsl4p with the exosome is mediated by protein-protein interactions with hRrp42p (show EXOSC7 Proteins) and hRrp46p

  4. These results in our study indicates gene silencing of SOCS1 (show SOCS1 Proteins) remarkably enhanced the cytotoxicity efficiency of CML28 DNA vaccine in DCs.

  5. Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase (show PNPT1 Proteins)-like ring.

EXOSC5 Protein Profile

Protein Summary

Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes (By similarity).

Gene names and symbols associated with Exosome Component 5 Proteins (EXOSC5)

  • exosome component 5 (exosc5)
  • exosome component 5 (EXOSC5)
  • exosome component 5 (Exosc5)
  • D7Wsu180e protein
  • EXOSC5 protein
  • hRrp46p protein
  • p12B protein
  • RRP41B protein
  • RRP46 protein
  • Rrp46p protein
  • si:ch211-194n6.2 protein
  • zgc:153707 protein

Protein level used designations for Exosome Component 5 Proteins (EXOSC5)

exosome complex exonuclease RRP46 , exosome component 5 , chronic myelogenous leukemia tumor antigen 28 , exosome complex component RRP46 , exosome component Rrp46 , ribosomal RNA-processing protein 46

GENE ID SPECIES
751632 Danio rerio
100138962 Bos taurus
56915 Homo sapiens
27998 Mus musculus
308441 Rattus norvegicus
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