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EXOSC6 product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. Additionally we are shipping EXOSC6 Antibodies (30) and many more products for this protein.
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We have recently identified increased expression of p11 genes that implicate fibrinolysis in ALD progression.
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase (show PNPT1 Proteins)-like ring.
This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.
homolog of yeast mRNA transport regulator 3
, exosome complex component MTR3
, exosome complex exonuclease MTR3
, exosome component 6
, mRNA transport regulator 3 homolog
, Mtr3 (mRNA transport regulator 3)-homolog
, mRNA transport regulator 3