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EXOSC8 encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. Additionally we are shipping Exosome Component 8 Antibodies (30) and Exosome Component 8 Proteins (9) and many more products for this protein.
Knock-down of rbm7 (show RBM7 ELISA Kits), exosc8 and exosc3 (show EXOSC3 ELISA Kits) in zebrafish showed a common pattern of defects in motor neurons and cerebellum. Our data indicate that impaired RNA metabolism may underlie the clinical phenotype by fine tuning gene expression which is essential for correct neuronal differentiation
A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity.
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase (show PNPT1 ELISA Kits)-like ring.
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
exosome complex exonuclease RRP43
, Opa-interacting protein 2 (3' exoribonuclease family)
, exosome component 8
, exosome complex component RRP43
, CBP-interacting protein 3
, Opa interacting protein 2
, opa-interacting protein 2
, ribosomal RNA-processing protein 43