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EXTL3 encodes a single-pass membrane protein which functions as a glycosyltransferase. Additionally we are shipping Exostoses (Multiple)-Like 3 Proteins (8) and Exostoses (Multiple)-Like 3 Kits (2) and many more products for this protein.
Showing 10 out of 82 products:
Human Polyclonal EXTL3 Primary Antibody for EIA, IHC (p) - ABIN952147
Levetan, Upham, Deng, Laury-Kleintop, Kery, Nolan, Quinlan, Torres, El-Hajj: Discovery of a human peptide sequence signaling islet neogenesis. in Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2009
Show all 5 references for ABIN952147
Human Polyclonal EXTL3 Primary Antibody for FACS, IHC (p) - ABIN952148
Kaidonis, Liaw, Roberts, Ly, Anson, Byers: Gene silencing of EXTL2 and EXTL3 as a substrate deprivation therapy for heparan sulphate storing mucopolysaccharidoses. in European journal of human genetics : EJHG 2010
Show all 2 references for ABIN952148
Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation.
Results suggest that all three Drosophila EXT proteins -- tout-velu, brother of tout-velu, and sister of tout-velu -- are required for the biosynthesis of heparan sulfate proteoglycans, and for the gradient formation of morphogens.
Regenerating islet-derived 1alpha (Reg (show KCNH2 Antibodies)-1alpha) protein is new neuronal secreted factor that stimulates neurite outgrowth via exostosin Tumor-like 3 (EXTL3) receptor.
EXTL3 expression is developmentally regulated, and contributes to the regulated production of heparan sulfate in different adult and embryonic tissues of mice.
EXTL3 expression at different grades in the central and peripheral nervous system components including the neural retina and neural crest-derived structures at embryonic days (E) 11.5, E12.5, E14.5, and E16.5.
Recombinant EXTL2 (show EXTL2 Antibodies) showed weak ability to transfer N-acetylgalactosamine to heparan sulfate precursor molecules but also, that EXTL2 (show EXTL2 Antibodies) exhibited much stronger in vitro N-acetylglucosamine-transferase activity related to elongation of heparan sulfate chains.
Regenerating islet-derived 1alpha (Reg-1alpha) protein is new neuronal secreted factor that stimulates neurite outgrowth via exostosin Tumor-like 3 (EXTL3) receptor.
Lysosomal glycosaminoglycan levels in mucopolysaccharidosis are reduced by EXTL3 gene silencing.
We conclude that EXTL3 promoter methylation and its related loss of EXTL3 expression are involved in the loss of HS expression in mucinous CRCs.
HIP enhanced EXTL3 translocation from the membrane to the nucleus, in support of a model whereby EXTL3 mediates HIP signaling for islet neogenesis.
A missense mutation involving the exon 3 of the EXTL3 gene in the case of obstructing colon cancer is described in a 31-year-old patient affected by hereditary multiple exostoses.
These results suggest that EXTL3/EXTR1 is a cell surface Reg receptor that binds to Reg protein.
This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants.
, brother of tout velu
, drosophila Ext-like 3
, exostoses-like 3
, exostosin-like 3
, glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
, multiple exostosis-like protein 3
, EXT-related 1
, exostoses (multiple)-like 3
, exostosin tumor-like 3
, hereditary multiple exostoses gene isolog
, putative tumor suppressor protein EXTL3
, reg receptor
, Reg receptor