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anti-Exostosin 1 (EXT1) Antibodies

EXT1 encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Additionally we are shipping EXT1 Kits (13) and EXT1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EXT1 14042 P97464
EXT1 2131 Q16394
EXT1 299907  
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Top anti-EXT1 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of EXT1 Antibody (Center) in K562 cell line lysates (35ug/lane). This demonstrates the EXT1 antibody detected the EXT1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB EXT1 Antibody (Center)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EXT1 antibody detected the EXT1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, WB Western Blot analysis of EXT1 expression in transfected 293T cell line by EXT1 MaxPab polyclonal antibody.Lane 1: EXT1 transfected lysate(86.30 KDa).Lane 2: Non-transfected lysate. EXT1 MaxPab rabbit polyclonal antibody. Western Blot analysis of EXT1 expression in human liver. 100 μg Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged EXT1 is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details
Human Rabbit Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 6 Days
$302.50
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using EXT1 antibody. 100 μL Log in to see 9 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details

EXT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


Human , ,
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Rat (Rattus)


Top referenced anti-EXT1 Antibodies

  1. Human Polyclonal EXT1 Primary Antibody for EIA, WB - ABIN952144 : Zuntini, Pedrini, Parra, Sgariglia, Gentile, Pandolfi, Alberghini, Sangiorgi: Genetic models of osteochondroma onset and neoplastic progression: evidence for mechanisms alternative to EXT genes inactivation. in Oncogene 2010 (PubMed)
    Show all 3 references for ABIN952144

  2. Human Polyclonal EXT1 Primary Antibody for IF, WB - ABIN515425 : Tian, Yan, Wen, Li, Li, Cai, Li, Du, Chen: A splice mutation and mRNA decay of EXT2 provoke hereditary multiple exostoses. in PLoS ONE 2014 (PubMed)

  3. Human Polyclonal EXT1 Primary Antibody for WB - ABIN2161060 : de Andrea, Reijnders, Kroon, de Jong, Hogendoorn, Szuhai, Bovée: Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXT. in Oncogene 2012 (PubMed)

More Antibodies against EXT1 Interaction Partners

Zebrafish Exostosin 1 (EXT1) interaction partners

  1. the three zebrafish ext1 genes encode proteoglycan (show Vcan Antibodies) modifying enzymes and have distinct relationships to somitic Sonic hedgehog (show SHH Antibodies) signaling

Mouse (Murine) Exostosin 1 (EXT1) interaction partners

  1. Normal heparin sulfate levels and Ext1 activity in the stromal microenvironment and hematopoietic stem cells are required for the transplant engraftment following non-myeloablative conditioning.

  2. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  3. Ext genes and heparan sulfate are needed to establish and maintain perichondrium's phenotype and border function.

  4. Levels of Ext1 and HPSE (show HPSE Antibodies) influence the motility of FBJ osteosarcoma cells.

  5. stromal Ext1-levels modulate tumor cell proliferation and affect the interstitial fluid pressure in a 3-D spheroid model.

  6. The study indicates that formation of stereotypic exostoses requires a significant, but not complete, loss of Ext expression.

  7. local Ext1 expression and heparan sulfate production are needed to maintain the phenotype and function of joint-forming cells.

  8. Ext1 has a role in regulation of bone morphogenic protein signaling and skeletal defects

  9. inactivation of Ext1 in a small fraction of chondrocytes is sufficient for the development of osteochondromas and other skeletal defects associated with multiple hereditary exostoses

  10. for a model of multiple osteochondromas, we created the chimeric tissue genotype of somatic loss of heterozygosity, by conditionally inactivating Ext1 in chondrocytes

Human Exostosin 1 (EXT1) interaction partners

  1. We found that the prevalence of EXT1 mutations was greater than that of EXT2 mutations in Japanese multiple osteochondromas families.

  2. Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans

  3. EXT1 mutation is associated with multiple osteochondromatosis.

  4. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  5. there is a putative genetic connection between TCF7L2 and EXT in the context of Hereditary Multiple Exostoses

  6. loss of function of EXT1 subjects with hereditary multiple exostoses affects pancreatic insulin (show INS Antibodies) secretion capacity and development.

  7. Results provide a new frameshift mutation in EXT1, further emphasizing the dysfunction of the EXT gene family as a cause of hereditary multiple exostosis.

  8. exostosin 1 (EXT1), which is involved in biosynthesis of heparan sulfate, plays a role in filovirus entry

  9. EXT1 and EXT2 heterozygous mutations in 18 (54.6 %) and ten (30.3 %) probands respectively, which represents a total of 28 (84.9 %) index cases.

  10. a novel disease-causing EXT1 mutation in a pedigree with Hereditary multiple exostoses

EXT1 Antigen Profile

Protein Summary

This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses.

Gene names and symbols associated with anti-Exostosin 1 (EXT1) Antibodies

  • exostoses (multiple) 1b (ext1b) antibody
  • exostoses (multiple) 1 (Ext1) antibody
  • exostoses (multiple)-like 1 (EXTL1) antibody
  • exostosin 1 (EXT1) antibody
  • exostosin glycosyltransferase 1 (EXT1) antibody
  • exostosin glycosyltransferase 1 (Ext1) antibody
  • exostosin glycosyltransferase 1 (ext1) antibody
  • exostosin-1-like (LOC100537794) antibody
  • AA409028 antibody
  • EXT antibody
  • LGCR antibody
  • LGS antibody
  • TRPS2 antibody
  • TTV antibody
  • xext1 antibody

Protein level used designations for anti-Exostosin 1 (EXT1) Antibodies

exostosin-1b , glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1b , multiple exostoses protein 1 homolog b , exostosin-1 , glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase , multiple exostoses protein 1 homolog , Heparan sulfate copolymerase , Multiple exostoses protein 1 homolog , exostosin 1 , exostoses-like 1 , Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase , exostoses (multiple) 1 , Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase , Langer-Giedion syndrome chromosome region , N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase , multiple exostoses protein 1 , putative tumor suppressor protein EXT1

GENE ID SPECIES
497280 Danio rerio
14042 Mus musculus
100689334 Cricetulus griseus
100347418 Oryctolagus cuniculus
538602 Bos taurus
2131 Homo sapiens
299907 Rattus norvegicus
399115 Xenopus laevis
100537794 Danio rerio
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