anti-Extracellular Matrix Protein 1 (ECM1) Antibodies

ECM1 encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. Additionally we are shipping ECM1 Kits (42) and ECM1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ECM1 1893 Q16610
ECM1 13601 Q61508
ECM1 116662 Q62894
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Top anti-ECM1 Antibodies at antibodies-online.com

Showing 10 out of 91 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, EM, FACS, ICC, IF, IHC, IHC (fro), IHC (p), IP Immunocytochemistry/Immunofluorescence: ECM-1/Secretory Component P85 Antibody (SC05) [NBP2-29464] - Immunohistochemistry-Paraffin: Secretory Component / ECM1 Antibody (SC05) [NBP2-29464] - Formalin-fixed, paraffin-embedded normal human intestine (20X) stained with MUC2 antibody (1:200), peroxidase-conjugate and DAB chromogen. Immunohistochemistry-Paraffin: ECM-1/Secretory Component P85 Antibody (SC05) [NBP2-29464] - Formalin-fixed, paraffin-embedded normal human intestine (10X) stained with MUC2 antibody (1:200), peroxidase-conjugate and DAB chromogen. 0.1 mg Log in to see 8 to 11 Days
$447.56
Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse endometrium tissue labeled with Anti-ECM1 Polyclonal Antibody, Unconjugated (ABIN673071) at 1:300, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse endometrium tissue labeled with Anti-ECM1 Polyclonal Antibody, Unconjugated  at 1:300, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 16 Days
$460.63
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Secretory Component / ECM1 Antibody [NBP1-87449] - Staining of human kidney shows distinct cytoplasmic positivity in tubular cells combined with extra cellular immunoreactivity. Western Blot: Secretory Component / ECM1 Antibody [NBP1-87449] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted) 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Mouse Un-conjugated IHC (fro), IHC (p), IP, WB   100 μg Log in to see 7 to 9 Days
$881.83
Details
Human Mouse Un-conjugated FACS, ICC, IF, IHC (p)   0.02 mg Log in to see 8 to 11 Days
$187.69
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$218.90
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$273.90
Details

ECM1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ECM1 Antibodies

  1. Human Monoclonal ECM1 Primary Antibody for ELISA, EM - ABIN4306907 : Tang, Tao, Yun-Liu, Sun, Geng, Jiang: Immunocytochemical localization of secretory component in Paneth cell secretory granules-rat Paneth cells participate in acquired immunity. in Journal of molecular histology 2005 (PubMed)
    Show all 7 references for 4306907

More Antibodies against ECM1 Interaction Partners

Human Extracellular Matrix Protein 1 (ECM1) interaction partners

  1. our work has identified a novel function of ECM1 in inhibiting Th17 cell differentiation in the experimental autoimmune encephalomyelitis model

  2. ECM1, which displayed a high expression in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) specimens, was closely associated with clinicopathologic data and may promote migration and invasion of HCC (show FAM126A Antibodies) cells by inducing epithelia-mesenchymal transition.

  3. Cell invasion (matrigel) was reduced only in the Hs578T cells (p < 0.01). Silencing decreased the expression of the prometastatic molecules S100A4 (show S100A4 Antibodies) and TGFbetaR2 in both cell lines and CD44 (show CD44 Antibodies) in Hs578T cells. We conclude that ECM1 is a key player in the metastatic process and regulates the actin cytoskeletal architecture of aggressive breast cancer cells at least in part via alterations in S100A4 (show S100A4 Antibodies) and Rho A (show RHOA Antibodies).

  4. Overexpression of miR (show MLXIP Antibodies)-486-3p inhibited cell growth and metastasis by targeting ECM1.

  5. For 1q21 loci, we confirmed gene ECM1 as the most plausible gene from this region to be involved in pathogenesis of inflammatory bowel disease

  6. In conclusion, the domain-specific anti-ECM1 MAbs produced in this study should provide a useful tool for investigating ECM1's biological functions, and cellular pathways in which it is involved.

  7. Lipoid proteinosis is a rare autosomal recessive disorder caused by mutations in ECM1, encoding extracellular matrix protein 1, a glycoprotein expressed in many organs and which has important protein-protein interactions in tissue homeostasis

  8. MMP-2 (show MMP2 Antibodies) protein and ECM1 gene are useful preoperative markers for defining malignancy in suspicious thyroid nodules

  9. association between beta-catenin (show CTNNB1 Antibodies) and the MUC1 (show MUC1 Antibodies) cytoplasmic tail was increased by ECM1

  10. Lipoidproteinosis results from a large homozygous deletion of ECM1 gene in a Chinese family.

Mouse (Murine) Extracellular Matrix Protein 1 (ECM1) interaction partners

  1. ECM1 seems to be critical for PTHrP (show PTHLH Antibodies) action in chondrogenesis, as blockage of ECM1 nearly abolishes PTHrP (show PTHLH Antibodies) regulation of chondrocyte hypertrophy, and overexpression of ECM1 rescues disorganized growth plates of PTHrP (show PTHLH Antibodies)-null mice; ECM1 and progranulin (show GRN Antibodies) chondrogenic growth factor constitute an interaction network.

  2. HA accumulation primes the vasculature for atherosclerosis by crosslinking and reorganizing the extracellular matrix (ECM (show MMRN1 Antibodies)) and by pushing VSMC differentiation towards a less mature phenotype.

  3. Retinoid signaling in the stroma activates expression of Ecm1, which in turn down-regulates Ret (show RET Antibodies) expression in the ureteric bud cleft, where bifurcation normally occurs and normal branching progresses.

ECM1 Antigen Profile

Protein Summary

This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.

Gene names and symbols associated with ECM1

  • extracellular matrix protein 1 (ECM1) antibody
  • extracellular matrix protein 1 (Ecm1) antibody
  • AI663821 antibody
  • p85 antibody
  • URBWD antibody

Protein level used designations for ECM1

extracellular matrix protein 1 , secretory component p85

GENE ID SPECIES
707209 Macaca mulatta
746939 Pan troglodytes
100437948 Pongo abelii
1893 Homo sapiens
13601 Mus musculus
116662 Rattus norvegicus
608791 Canis lupus familiaris
524222 Bos taurus
100338579 Oryctolagus cuniculus
100721378 Cavia porcellus
100620701 Sus scrofa
100858704 Gallus gallus
101105541 Ovis aries
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