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F-Box Protein 2 Proteins (FBXO2)

FBXO2 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Additionally we are shipping F-Box Protein 2 Antibodies (53) and F-Box Protein 2 Kits (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FBXO2 26232 Q9UK22
FBXO2 230904 Q80UW2
Rat FBXO2 FBXO2 85273  
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Top F-Box Protein 2 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,786.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FBXO2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for F-Box Protein 2 (FBXO2) Interaction Partners

Human F-Box Protein 2 (FBXO2) interaction partners

  1. Although the overall structure of FBG3 (show FBXO44 Proteins) is similar to that of Fbs1, the residues that form the Fbs1 carbohydrate-binding pocket failed to be superposed with the corresponding residues of FBG3 (show FBXO44 Proteins).

  2. FBG1 degrades A1AT (show SERPINA1 Proteins)-Z through a Beclin1 (show BECN1 Proteins)-dependent arm of autophagy.

  3. FBG1 is unique among known F-box proteins in that it contains a non-canonical D-Box within F-box domain, required for the growth arrest.

  4. interaction of the HSV-1 UL9 protein with NFB42 results in its polyubiquitination and subsequent degradation by the 26S proteasome (show Psmd4 Proteins)

Mouse (Murine) F-Box Protein 2 (FBXO2) interaction partners

  1. FBG1 degrades A1AT (show SERPINA1 Proteins)-Z through a Beclin1 (show BECN1 Proteins)-dependent arm of autophagy.

  2. The results of this study suggested that Fbxo2 controls the abundance and localization of specific NMDAR (show GRIN1 Proteins) subunits in the brain and may influence synapse formation and maintenance.

  3. these results suggest that Fbxo2 regulates APP (show APP Proteins) levels and processing in the brain and may play a role in modulating Alzheimer disease pathogenesis.

  4. our studies support a non-essential role for FBG1 on the degradation of torsinA (show TOR1A Proteins) and uncover a novel link of FBG1 to the autophagy pathway.

  5. When expressed in hippocampal neurons, the Fbx2 dominant-negative mutant augmented NR1 subunit levels and NMDA receptor-mediated currents in an activity-dependent fashion

  6. Fbs1 assists clearance of aberrant glycoproteins in neuronal cells by suppressing aggregates formation, independent of ubiquitin ligase activity, and thus functions as a unique chaperone for those proteins.

  7. Our findings demonstrate that components of protein quality control are essential for inner ear homeostasis and implicate Fbx2 and Skp1 (show SKP1 Proteins) as potential genetic modifiers in age-related hearing loss.

F-Box Protein 2 (FBXO2) Protein Profile

Protein Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state.

Gene names and symbols associated with F-Box Protein 2 Proteins (FBXO2)

  • F-box protein 2 (FBXO2)
  • F-box protein 2 (Fbxo2)
  • FBG1 protein
  • Fbs1 protein
  • Fbs2 protein
  • FBX2 protein
  • NFB42 protein
  • OCP1 protein
  • Prpl4 protein

Protein level used designations for F-Box Protein 2 Proteins (FBXO2)

F-box only protein 2 , F-box gene 1 , organ of Corti protein 1 , prion protein ligand 4 , neural F box protein NFB42

GENE ID SPECIES
457951 Pan troglodytes
26232 Homo sapiens
230904 Mus musculus
85273 Rattus norvegicus
512589 Bos taurus
478231 Canis lupus familiaris
419495 Gallus gallus
101112079 Ovis aries
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