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Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. Additionally we are shipping F-Box Protein 42 Antibodies (45) and F-Box Protein 42 Kits (15) and many more products for this protein.
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SCF (show KITLG Proteins)(JFK) as a bona fide E3 ligase for ING4 (show ING4 Proteins) and unraveled the JFK-ING4 (show ING4 Proteins)-NF-kappaB (show NFKB1 Proteins) axis as an important player in the development and progression of breast cancer
The findings of this study suggest that a haplotype of the FBXO42 gene might be associated with a higher susceptibility to PD.
Substrate phosphorylation and feedback regulation in JFK-promoted p53 (show TP53 Proteins) destabilization.
JFK promotes p53 (show TP53 Proteins) turnover through assembly of an SCF (show KITLG Proteins) (Skp1 (show SKP1 Proteins)-Cul1 (show CUL1 Proteins)-F-box) complex, revealing a pathway for the control of p53 (show TP53 Proteins) degradation and providing a link between the SCF (show KITLG Proteins) complex and p53 (show TP53 Proteins) regulation.
Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A\; MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box protein 42
, F-box only protein 42-like
, F-box only protein 42
, just one F-box and Kelch domain-containing protein