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Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. Additionally we are shipping F-Box Protein 43 Antibodies (35) and F-Box Protein 43 Proteins (3) and many more products for this protein.
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Cdc2 (show CDK1 ELISA Kits) and Mos (show MOS ELISA Kits) regulate Emi2 stability to promote the meiosis I-meiosis II transition
These results suggest that in addition to the Mos (show MOS ELISA Kits)-MEK1 (show MAP2K1 ELISA Kits)/2 pathway, the Mos (show MOS ELISA Kits)-mediated p38 (show CRK ELISA Kits) pathway may be implicated in metaphase-II arrest.
data support the conclusion that zinc itself, through its interaction with EMI2, is a central component of the cytostatic factor
phosphorylation was required for up-regulation of the EMI2 activity in the oocytes. These results suggest that mouse MSK1 (show RPS6KA5 ELISA Kits) may play a key role in the metaphase-II arrest through phosphorylation of EMI2
separable N- and C-terminal domains of mouse Emi2 modulated metaphase establishment and maintenance, respectively, through indirect and direct mechanisms.
the APC (show APC ELISA Kits)/C-inhibitory activity of XErp1 (also known as Emi2) was essential for early divisions in Xenopus embryos.
Thus, Mos (show MOS ELISA Kits) and Erp1 collaboratively establish and maintain metaphase II arrest in Xenopus eggs
Emi2 stability and activity are dynamically regulated by Emi2-bound multiple kinases and PP2A phosphatase.
Erp1/Emi2 is essential for the meiosis I to meiosis II transition in Xenopus oocytes.
Emi2 directs meiosis II-specific cytostatic factor cell cycle arrest.
Emi2/XErp1 is the critical cytostatic factor component directly responsible for anaphase-promoting complex/cyclosome inhibition during CSF (show CSF2 ELISA Kits) arrest.
These findings provide a novel mechanism of APC (show APC ELISA Kits)/C inhibition wherein the final step of ubiquitin transfer is targeted and raise the interesting possibility that APC (show APC ELISA Kits)/C is inhibited by Emi2 in a catalytic manner.
Data show that Emi2 binds the anaphase-promoting complex/cyclosome via the C-terminal tail.
review mechanism of action and mode of regulation of Emi2, CSF (show CSF2 ELISA Kits) function, and the general principles of APC (show APC ELISA Kits)/C regulation and control of protein function by MAPK (show MAPK1 ELISA Kits) pathways [review]
Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box protein 43
, F-box only protein 43-like
, f-box only protein 43-like
, F-box only protein 43
, early mitotic inhibitor 2
, endogenous meiotic inhibitor 2
, XErp1 homolog
, F-box protein 26
, emi1-related protein 1
, protocadherin Fat 2