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F-Box Protein 7 Proteins (FBXO7)

FBXO7 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Additionally we are shipping F-Box Protein 7 Antibodies (22) and F-Box Protein 7 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FBXO7 25793 Q9Y3I1
FBXO7 69754 Q3U7U3
Rat FBXO7 FBXO7 366854 Q68FS3
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Top F-Box Protein 7 Proteins at

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days

FBXO7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for F-Box Protein 7 (FBXO7) Interaction Partners

Zebrafish F-Box Protein 7 (FBXO7) interaction partners

  1. analysis of the zebrafish model of Fbxo7 mutations with a role in levodopa-responsive parkinsonism with severe loss of nigrostriatal dopaminergic neurons

Human F-Box Protein 7 (FBXO7) interaction partners

  1. The mutations of F-box protein 7 (FBXO7) gene (T22M, R378G and R498X) are associated with autosomal recessive juvenile-onset Parkinson's disease We demonstrated wild-type FBXO7 is a stress response protein with both cytoprotective and neurotoxic roles

  2. This is first time a FBXO7 mutation has been identified that causes phenotype compatible with typical idiopathic Parkinson's disease and presents with some of its common nonmotor features

  3. High expression of PARK15 might lead to the occurrence of non-small-cell lung cancer.

  4. genetic analysis of this Turkish family and the Italian PARK15 family reported previously revealed that the c.1492C > T mutation is present on two different haplotypes in the Italian family

  5. in addition to the parkinsonian-pyramidal phenotype, in connection with FBXO7 mutations and points to an intrafamilial phenotypic variation

  6. Cys52 variant of FBXO7 may contribute to reduced Parkinson's disease susceptibility in Chinese

  7. The involvement of the FBXO7 gene in PD is very rare, at least in this population from southern Spain.

  8. The crystal structure of the Fbxo7 FP domain is reported at 2.0 A resolution. The Fbxo7 FP domain adopts an alpha/beta-fold similar to that of the PI31 (show PSMF1 Proteins) FP domain.

  9. A mutational analysis of the FBXO7 gene in Taiwanese patients with Parkinson's disease (PD) does not show a potential pathophysiological role in PD.

  10. This study showed that Fbxo7 participates in mitochondrial maintenance through direct interaction with PINK1 (show PINK1 Proteins) and Parkin (show PARK2 Proteins) and acts in Parkin (show PARK2 Proteins)-mediated mitophagy.

Mouse (Murine) F-Box Protein 7 (FBXO7) interaction partners

  1. Report defective erythropoiesis in transgenic mouse with reduced Fbxo7 expression due to decreased erythrocyte p27 (show CDKN1B Proteins) expression.

  2. 2 PDX models showed gained mutations such as PIK3CA (show PIK3CA Proteins) or FBWX7 mutation. Ten patient-derived advanced colon cancer xenograft models were established.

  3. The physiological effect of reduced levels of Fbxo7 in mice showed significantly increased pro-B cell and pro-erythroblast populations, consistent with Fbxo7 having an anti-proliferative function and/or a role in promoting maturation of precursor cells.

  4. Fbxo7 specifically regulated D cyclin (show PCNA Proteins)/cdk6 (show CDK6 Proteins) complexes; it was highly expressed in epithelial tumors, but not in normal tissues, suggesting that it may have a proto-oncogenic role in human cancers.

F-Box Protein 7 (FBXO7) Protein Profile

Protein Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

Gene names and symbols associated with F-Box Protein 7 Proteins (FBXO7)

  • F-box protein 7 (FBXO7)
  • F-box protein 7 (fbxo7)
  • F-box protein 7 (FBP7)
  • F-box protein 7 (Fbxo7)
  • 2410015K21Rik protein
  • A230052G17Rik protein
  • AI117679 protein
  • ATFBP7 protein
  • AW260462 protein
  • C85118 protein
  • DKFZp469H0739 protein
  • F-box protein 7 protein
  • F8K7.20 protein
  • F8K7_20 protein
  • FBX protein
  • FBX07 protein
  • FBX7 protein
  • FBXO7 protein
  • MGC80085 protein
  • MGC135804 protein
  • MGC145325 protein
  • PARK15 protein
  • PKPS protein
  • si:ch211-286m4.2 protein
  • zgc:114096 protein

Protein level used designations for F-Box Protein 7 Proteins (FBXO7)

F-box only protein 7 , F-box protein 7 , F-box only protein 7-like

418063 Gallus gallus
474522 Canis lupus familiaris
446503 Xenopus laevis
470266 Pan troglodytes
717317 Macaca mulatta
780025 Xenopus (Silurana) tropicalis
838780 Arabidopsis thaliana
100016137 Monodelphis domestica
100135459 Papio anubis
100172444 Pongo abelii
100409679 Callithrix jacchus
100595350 Nomascus leucogenys
558097 Danio rerio
25793 Homo sapiens
100155281 Sus scrofa
508235 Bos taurus
100328739 Oryctolagus cuniculus
69754 Mus musculus
366854 Rattus norvegicus
101118684 Ovis aries
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