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FBXO9 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Additionally we are shipping F-Box Protein 9 Kits (12) and F-Box Protein 9 Proteins (5) and many more products for this protein.
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ICK (show ICK Antibodies) and FBX9 are divergently transcribed from a bidirectional promoter that is GC-rich (show RELB Antibodies) and contains a CpG island.
FBXO9 directly interacted with PPAR gamma (show PPARG Antibodies) through the activation function-1 domain and ligand-binding domain. FBXO9 decreased the protein stability of PPAR gamma (show PPARG Antibodies) through induction of ubiquitination.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus.
F-box protein 9
, F-box only protein 9
, f-box only protein 9-like
, F-box protein Fbx9
, cross-immune reaction antigen 1
, renal carcinoma antigen NY-REN-57