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F-Box and WD Repeat Domain Containing 11 Proteins (FBXW11)

FBXW11 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Additionally we are shipping FBXW11 Antibodies (65) and FBXW11 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat FBXW11 FBXW11 303024  
FBXW11 23291 Q9UKB1
FBXW11 103583 Q5SRY7
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Top FBXW11 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FBXW11 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for F-Box and WD Repeat Domain Containing 11 (FBXW11) Interaction Partners

Human F-Box and WD Repeat Domain Containing 11 (FBXW11) interaction partners

  1. SCF(FBXW11) bound, polyubiquitylated, and destabilized RAPGEF2, a guanine nucleotide exchange factor that activates the small GTPase RAP1

  2. Data indicate that miR (show MLXIP Proteins)-106b-25 cluster (miR (show MLXIP Proteins)-106b, miR (show MLXIP Proteins)-93 and miR (show MLXIP Proteins)-25) targets the 3'UTR of the beta-TRCP2 transcript and increases the expression of Snail (show SNAI1 Proteins).

  3. Knockdown of beta-TrCP1 (show BTRC Proteins) and beta-TrCP2 attenuated the K48-linked ubiquitination and degradation of IRAK1 (show IRAK1 Proteins).

  4. two splice variants of beta-transducin repeat containing protein 2 (BTRCP2) localise exclusively to either the nucleus or the cytosol.

  5. Data indicate that knockdown of beta-TrCP1 and beta-TrCP2 markedly reduced IL-17-induced, phosphorylation-dependent ubiquitination and degradation of Act1.

  6. FBXW11 may be the most likely candidate gene for the Holoprosencephaly and prexial polydactyly phenotype.

Mouse (Murine) F-Box and WD Repeat Domain Containing 11 (FBXW11) interaction partners

  1. The mTOR pathway promotes cell proliferation via beta-TrCP2-dependent p19(Arf) degradation under nutrient-rich conditions.

  2. Data show that beta-TrCP2 and beta-TrCP1 (show BTRC Proteins) target PER2 (show PER2 Proteins) protein in vitro, and also show that the beta-TrCP (show BTRC Proteins) binding site of PER2 (show PER2 Proteins) is recognized by both beta-TrCP1 (show BTRC Proteins) and beta-TrCP2 [beta-TrCP2].

FBXW11 Protein Profile

Protein Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

Gene names and symbols associated with FBXW11

  • F-box and WD repeat domain containing 11 (Fbxw11)
  • F-box and WD repeat domain containing 11 (FBXW11)
  • F-box and WD repeat domain containing 11 (fbxw11)
  • F-box and WD-40 domain protein 11 (Fbxw11)
  • F-box and WD-40 domain protein 11b (fbxw11b)
  • 2310065A07Rik protein
  • AA536858 protein
  • btrc2 protein
  • BTRCP2 protein
  • FBW1B protein
  • Fbw11 protein
  • Fbxw1b protein
  • fbxw11a protein
  • HOS protein
  • wu:fa12e12 protein
  • wu:fb11f03 protein
  • zgc:63728 protein

Protein level used designations for FBXW11

F-box/WD repeat-containing protein 11 , F-box and WD-40 domain protein 11 , F-box and WD repeat domain containing 11 , f-box/WD repeat-containing protein 11-like , F-box and WD repeats protein beta-TrCP2 , F-box and WD-40 domain protein 1B , F-box protein Fbw1b , F-box/WD repeat-containing protein 1B , beta-transducin repeat-containing protein 2 , homologous to Slimb protein , fbxw11

GENE ID SPECIES
303024 Rattus norvegicus
462263 Pan troglodytes
708990 Macaca mulatta
100069972 Equus caballus
100199403 Hydra magnipapillata
100217770 Taeniopygia guttata
100402300 Callithrix jacchus
100479018 Ailuropoda melanoleuca
100605260 Nomascus leucogenys
23291 Homo sapiens
416181 Gallus gallus
479291 Canis lupus familiaris
540642 Bos taurus
100340737 Oryctolagus cuniculus
100715997 Cavia porcellus
101107136 Ovis aries
103583 Mus musculus
406825 Danio rerio
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