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anti-FAT Tumor Suppressor Homolog 1 (Drosophila) (FAT1) Antibodies

FAT1 is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FAT1 2195 Q14517
FAT1 14107  
FAT1    
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Top anti-FAT Tumor Suppressor Homolog 1 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, WB   100 μL Log in to see 9 to 11 Days
$275.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of Recombinant protein, using FAT1 Polyclonal Antibody at dilution of 1:2000 200 μL Log in to see 8 to 9 Days
$588.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry of Human thyroid cancer using FAT1 Polyclonal Antibody at dilution of 1:40 200 μL Log in to see 8 to 9 Days
$588.50
Details
Human Rabbit Un-conjugated ICC, WB 100 μg Log in to see 7 Days
$434.50
Details
Fruit Fly Mouse DyLight 650 ELISA, ICC, IF, WB   0.1 mL Log in to see 6 to 9 Days
$416.06
Details
Fruit Fly Mouse FITC ELISA, ICC, IF, WB   0.1 mL Log in to see 6 to 9 Days
$416.06
Details
Fruit Fly Mouse DyLight 550 ELISA, ICC, IF, WB   0.1 mL Log in to see 6 to 9 Days
$416.06
Details
Fruit Fly Mouse DyLight 350 ELISA, ICC, IF, WB   0.1 mL Log in to see 6 to 9 Days
$427.88
Details
Fruit Fly Mouse DyLight 405 ELISA, ICC, IF, WB   0.1 mL Log in to see 6 to 9 Days
$427.88
Details
Fruit Fly Mouse PE ELISA, ICC, IF, WB   0.1 mL Log in to see 6 to 9 Days
$427.88
Details

FAT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


Mouse (Murine) ,


Fruit Fly (Drosophila melanogaster)


, , , , , , , , , , , , , , , , ,

More Antibodies against FAT Tumor Suppressor Homolog 1 (Drosophila) Interaction Partners

Human FAT Tumor Suppressor Homolog 1 (Drosophila) (FAT1) interaction partners

  1. Recessive mutations in FAT1 cause a distinct renal disease entity in four families with a combination of steroid-resistance nephrotic syndrome, tubular ectasia, haematuria and facultative neurological involvement.

  2. that loss of FAT1 and beta-catenin (show CTNNB1 Antibodies) are associated with breast cancer progression, aggressive behavior, and poor prognosis

  3. FAT1 protein acts upstream of Hippo signalling through TAZ (show TAZ Antibodies) protein to regulate neuronal differentiation.

  4. Fat1 is released from pancreatic cancer cells in its soluble form by ADAM10 (show ADAM10 Antibodies) mediated ectodomain shedding

  5. our data suggest that defective FAT1 is associated with an FSHD-like phenotype.

  6. FAT1 is expressed at lower levels in muscles that are affected at early stages of facioscapulohumeral muscular dystrophy progression.

  7. Analysis revealed an aberrant expression of FAT1 predominantly in mature BCP (show OPN1SW Antibodies)-ALL and thymic T-ALL and a high rate of FAT1 mutations.

  8. FJX1 (show FJX1 Antibodies) does not influence the levels of FAT1 ectodomain phosphorylation.

  9. FAT1 expression in HCC (show FAM126A Antibodies) is regulated via promotor methylation.

  10. Fat1 may therefore provide a new marker of MRD for patients with ALL lacking known genomic aberrations or within a multiplex approach to MRD detection.

Mouse (Murine) FAT Tumor Suppressor Homolog 1 (Drosophila) (FAT1) interaction partners

  1. Fat1 deletion in podocytes induces abnormal glomerular filtration barrier development leading to podocyte foot process effacement. Fat1 knockdown in renal tubular cells reduces migration, decreases active RAC1/CDC42 (show CDC42 Antibodies) and induces defects in lumen formation.

  2. Fat1 interacts with Fat4 (show FAT4 Antibodies) to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development.

  3. Fat-1 expression suppresses CD4 (show CD4 Antibodies)+ T-cell activation and differentiation in spleen, and reduces inflammatory cytokines and eotaxin (show CCL11 Antibodies) in bronchoalveolar lavage and lung tissues of mice.

  4. Endogenous synthesis of n-3 PUFA in the fat-1 mouse attains similar kidney n-3 PUFA composition and eicosanoid levels as compared to fish oil feeding.

  5. FAT1 suppression in activated hepatic stellate cells caused a downregulation of NFkappaB activity

  6. Data find that Fat1 and Fat4 (show FAT4 Antibodies) cooperate during mouse development to control renal tubular elongation, cochlear extension, cranial neural tube formation and patterning of outer hair cells in the cochlea.

  7. results confirm a necessary role for FAT1 in the modified adhesion junctions of the renal glomerular epithelial cell and reveal hitherto unsuspected roles for FAT1 in CNS development

  8. Fat1 regulates actin cytoskeletal organization at cell peripheries, thereby modulating cell contacts and polarity.

  9. data are compatible with conservation and sub-functionalization of dachsous 1 (show DCHS1 Antibodies), Fj, and Fat signaling in higher vertebrates.

  10. FAT1(WT) is up-regulated in migration, induces cellular process formation when overexpressed, and is necessary for efficient wound healing

FAT Tumor Suppressor Homolog 1 (Drosophila) (FAT1) Antigen Profile

Protein Summary

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and\\/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and\\/or alternative promoter usage exist, but they have not been fully described.

Gene names and symbols associated with FAT1

  • FAT atypical cadherin 1 (FAT1) antibody
  • FAT tumor suppressor homolog 1 (Drosophila) (Fat1) antibody
  • FAT tumor suppressor homolog 1 (Drosophila) (FAT) antibody
  • FAT tumor suppressor homolog 1 (Drosophila) (FAT1) antibody
  • FAT tumor suppressor homolog 1 (Drosophila) (fat1) antibody
  • 2310038E12Rik antibody
  • AU023433 antibody
  • CDHF7 antibody
  • CDHR8 antibody
  • FAT antibody
  • FAT1 antibody
  • Fath antibody
  • hFat1 antibody
  • ME5 antibody
  • mFat1 antibody

Protein level used designations for FAT1

FAT tumor suppressor 1 , FAT tumor suppressor homolog 1 , cadherin ME5 , cadherin family member 7 , cadherin-related family member 8 , cadherin-related tumor suppressor homolog , protein fat homolog , protocadherin Fat 1 , fat 1 cadherin , FAT tumor suppressor homolog 1 (Drosophila) , fat1-like , protocadherin Fat 1-like

GENE ID SPECIES
2195 Homo sapiens
14107 Mus musculus
395168 Gallus gallus
475621 Canis lupus familiaris
508251 Bos taurus
703034 Macaca mulatta
760178 Strongylocentrotus purpuratus
100050525 Equus caballus
100154043 Sus scrofa
100175143 Ciona intestinalis
100407761 Callithrix jacchus
100471195 Ailuropoda melanoleuca
100489070 Xenopus (Silurana) tropicalis
100549464 Meleagris gallopavo
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