anti-FAT Tumor Suppressor Homolog 1 (Drosophila) (FAT1) Antibodies

FAT1 is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FAT1 2195 Q14517
FAT1 14107  
FAT1    
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Top anti-FAT Tumor Suppressor Homolog 1 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: FAT1 Antibody [NBP1-84566] - Staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells. 0.1 mL Log in to see 7 to 9 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, WB   100 μL Log in to see 13 to 16 Days
$275.00
Details
Human Rabbit Un-conjugated WB Western Blot: FAT1 Antibody [NBP2-32274] - Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-FAT1 antibody NBP2-32274 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated WB Western Blot: FAT1 Antibody [NBP2-32275] - Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-FAT1 antibody NBP2-32275 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Mouse Un-conjugated WB Human recombinant protein at 20 µg per lane, probed with bsm-51354M FAT1 (1634CT464.1.9) Monoclonal Antibody at 1:2000 dilution and 4℃ overnight incubation, followed by secondary antibody incubation for 60min at room temperature. 100 μL Log in to see 3 to 7 Days
$291.50
Details
Fruit Fly Mouse Un-conjugated ELISA, ICC, IF, IHC, WB   0.1 mg Log in to see 7 to 9 Days
$317.63
Details
Fruit Fly Mouse DyLight 488 ELISA, ICC, IF, WB   0.1 mL Log in to see 8 to 11 Days
$408.19
Details
Fruit Fly Mouse Alexa Fluor 647 ELISA, ICC, IF, WB   0.1 mL Log in to see 8 to 11 Days
$408.19
Details
Fruit Fly Mouse DyLight 680 ELISA, ICC, IF, WB   0.1 mL Log in to see 8 to 11 Days
$408.19
Details
Fruit Fly Mouse Alexa Fluor 405 ELISA, ICC, IF, WB   0.1 mL Log in to see 8 to 11 Days
$408.19
Details

FAT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,


Fruit Fly (Drosophila melanogaster) ,


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Top referenced anti-FAT Tumor Suppressor Homolog 1 (Drosophila) Antibodies

  1. Human Polyclonal FAT1 Primary Antibody for IHC, IHC (p) - ABIN4310666 : Caruso, Herberth, Bartoli, Puppo, Dumonceaux, Zimmermann, Denadai, Lebossé, Roche, Geng, Magdinier, Attarian, Bernard, Maina, Levy, Helmbacher: Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophy. in PLoS genetics 2013 (PubMed)
    Show all 2 references for 4310666

More Antibodies against FAT Tumor Suppressor Homolog 1 (Drosophila) Interaction Partners

Human FAT Tumor Suppressor Homolog 1 (Drosophila) (FAT1) interaction partners

  1. Disruption of MAPK/ERK (show MAPK1 Antibodies) pathway by FAT1 contributes the epithelial mesenchymal transformation in esophageal squamous cell carcinomas.

  2. Loss of function mutations in FAT1 and CASP8 (show CASP8 Antibodies) prevent cell adhesion and promote cell migration and proliferation in oral squamous cell carcinoma cell lines.

  3. We identified recurrent mutations in the novel penile cancer tumor suppressor genes CSN1(GPS1 (show GPS1 Antibodies)) and FAT1

  4. FAT1 and mAb198.3 may offer new therapeutic opportunities for CRC (show CALR Antibodies).

  5. Data show that the two N-terminal SH3 domains of SH3 domain containing ring finger 1 (SH3RF1 (show SH3RF1 Antibodies)) protein interact with FAT1 protein.

  6. At the molecular level, under hypoxia the FAT1 depletion-associated reduction in HIF1alpha (show HIF1A Antibodies) was due to compromised EGFR (show EGFR Antibodies)-Akt (show AKT1 Antibodies) signaling as well as increased VHL (show VHL Antibodies)-dependent proteasomal degradation of HIF1alpha (show HIF1A Antibodies).

  7. Low FAT1 expression was associated with poor prognosis in children with medulloblastoma. Furthermore, FAT1 may act on Wnt (show WNT2 Antibodies) signaling pathway to exert its antitumor effect

  8. Recessive mutations in FAT1 cause a distinct renal disease entity in four families with a combination of steroid-resistance nephrotic syndrome, tubular ectasia, haematuria and facultative neurological involvement.

  9. that loss of FAT1 and beta-catenin (show CTNNB1 Antibodies) are associated with breast cancer progression, aggressive behavior, and poor prognosis

  10. FAT1 protein acts upstream of Hippo signalling through TAZ (show TAZ Antibodies) protein to regulate neuronal differentiation.

Mouse (Murine) FAT Tumor Suppressor Homolog 1 (Drosophila) (FAT1) interaction partners

  1. studies suggest that Fat1 controls mitochondrial activity to restrain cell growth during the reparative, proliferative state induced by vascular injury. Given recent reports linking Fat1 to cancer, abnormal kidney and muscle development, and neuropsychiatric disease, this Fat1 function may have importance in other settings of altered cell growth and metabolism

  2. Fat1 deletion in podocytes induces abnormal glomerular filtration barrier development leading to podocyte foot process effacement. Fat1 knockdown in renal tubular cells reduces migration, decreases active RAC1/CDC42 (show CDC42 Antibodies) and induces defects in lumen formation.

  3. Fat1 interacts with Fat4 (show FAT4 Antibodies) to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development.

  4. Fat-1 expression suppresses CD4 (show CD4 Antibodies)+ T-cell activation and differentiation in spleen, and reduces inflammatory cytokines and eotaxin (show CCL11 Antibodies) in bronchoalveolar lavage and lung tissues of mice.

  5. Endogenous synthesis of n-3 PUFA in the fat-1 mouse attains similar kidney n-3 PUFA composition and eicosanoid levels as compared to fish oil feeding.

  6. FAT1 suppression in activated hepatic stellate cells caused a downregulation of NFkappaB activity

  7. Data find that Fat1 and Fat4 (show FAT4 Antibodies) cooperate during mouse development to control renal tubular elongation, cochlear extension, cranial neural tube formation and patterning of outer hair cells in the cochlea.

  8. results confirm a necessary role for FAT1 in the modified adhesion junctions of the renal glomerular epithelial cell and reveal hitherto unsuspected roles for FAT1 in CNS development

  9. Fat1 regulates actin cytoskeletal organization at cell peripheries, thereby modulating cell contacts and polarity.

  10. data are compatible with conservation and sub-functionalization of dachsous 1 (show DCHS1 Antibodies), Fj, and Fat signaling in higher vertebrates.

Pig (Porcine) FAT Tumor Suppressor Homolog 1 (Drosophila) (FAT1) interaction partners

  1. these data provide new insights into the mechanisms of the association between FAT1 and porcine cumulus cell apoptosis.

FAT Tumor Suppressor Homolog 1 (Drosophila) (FAT1) Antigen Profile

Protein Summary

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and\\/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and\\/or alternative promoter usage exist, but they have not been fully described.

Gene names and symbols associated with FAT1

  • FAT atypical cadherin 1 (FAT1) antibody
  • FAT tumor suppressor homolog 1 (Drosophila) (Fat1) antibody
  • FAT tumor suppressor homolog 1 (Drosophila) (FAT) antibody
  • FAT tumor suppressor homolog 1 (Drosophila) (FAT1) antibody
  • FAT tumor suppressor homolog 1 (Drosophila) (fat1) antibody
  • 2310038E12Rik antibody
  • AU023433 antibody
  • CDHF7 antibody
  • CDHR8 antibody
  • FAT antibody
  • FAT1 antibody
  • Fath antibody
  • hFat1 antibody
  • ME5 antibody
  • mFat1 antibody

Protein level used designations for FAT1

FAT tumor suppressor 1 , FAT tumor suppressor homolog 1 , cadherin ME5 , cadherin family member 7 , cadherin-related family member 8 , cadherin-related tumor suppressor homolog , protein fat homolog , protocadherin Fat 1 , fat 1 cadherin , FAT tumor suppressor homolog 1 (Drosophila) , fat1-like , protocadherin Fat 1-like

GENE ID SPECIES
2195 Homo sapiens
14107 Mus musculus
395168 Gallus gallus
475621 Canis lupus familiaris
508251 Bos taurus
703034 Macaca mulatta
760178 Strongylocentrotus purpuratus
100050525 Equus caballus
100154043 Sus scrofa
100175143 Ciona intestinalis
100407761 Callithrix jacchus
100471195 Ailuropoda melanoleuca
100489070 Xenopus (Silurana) tropicalis
100549464 Meleagris gallopavo
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