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The Fos gene family consists of 4 members FOSL1, and FOSL2. Additionally we are shipping FBJ Murine Osteosarcoma Viral Oncogene Homolog B Proteins (8) and FBJ Murine Osteosarcoma Viral Oncogene Homolog B Kits (4) and many more products for this protein.
Showing 10 out of 88 products:
Cow (Bovine) Polyclonal FOSB Primary Antibody for IHC, WB - ABIN2779692
Holmes, Zachary: Placental growth factor induces FosB and c-Fos gene expression via Flt-1 receptors. in FEBS letters 2004
Human Polyclonal FOSB Primary Antibody for FACS, WB - ABIN1882084
Li, Fu, Wang, Tie, Xing, Zhu, Sun, Wei, Zheng: MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma. in Hepatology (Baltimore, Md.) 2009
studies of FosB are providing new insight into the molecular basis of depression and antidepressant action.
The abnormalities were screened by FISH in 44 epithelioid hemangioma (EH) from different locations with seven additional EH revealing FOSB gene rearrangements, all except one being fused to ZFP36 (show ZFP36 Antibodies).
This study describing the expres-sion pattern of FosB/ FosB immunoreactivity inpost mortem basal ganglia sections from Parkinson disease patients.
Pseudomyogenic haemangioendothelioma consistently displays a SERPINE1 (show SERPINE1 Antibodies)-FOSB fusion gene, resulting from a translocation between chromosomes 7 and 19.
Data indicate a significant correlation in miR (show MLXIP Antibodies)-181b, FOS and miR (show MLXIP Antibodies)-21 expression glioma tissues.
Report Fos-B expression in skin keratinocytes/fibroblasts and keloid fibroblasts exposed to genistein.
AP-1 protein induction during monopoiesis favors C/EBP (show CEBPA Antibodies): AP-1 heterodimers over C/EBP (show CEBPA Antibodies) homodimerization and stimulates FosB transcription.
Findings indicate that neurobehavioral stress leads to FosB-driven increases in IL8 (show IL8 Antibodies), which is associated with increased tumor growth and metastases.
transcription factor FosB/activating protein-1 (AP-1) activation is a prominent downstream signal of the extracellular nucleotide receptor P2RX7 (show P2RX7 Antibodies) in monocytic and osteoblastic cells
RGS16 (show RGS16 Antibodies) and FosB are underexpressed in pancreatic cancer with lymph node metastasis and associated with reduced survival
abnormal regulation of MSK1 (show RPS6KA5 Antibodies) contributes to the development of L-DOPA-induced dyskinesia and to the concomitant increase in striatal FosB, which may occur via increased histone H3 (show HIST3H3 Antibodies) phosphorylation at the fosB promoter
The most highly stereotypic mice showed the most elevated FosB/DeltaFosB activity in the nucleus accumbens
FosB/DeltaFosB immunoreactivity was transiently increased in hippocampus and parahippocampal cortices by 6-Hz corneal stimulation. FosB induction was primarily localized in pyramidal neurons.
Histone methylation or acetylation at the Fosb locus in nucleus accumbens, was sufficient to control drug- and stress-evoked behavioral responses.
Findings demonstrate that, under excitotoxicity, Fosb products contribute to a neuroinflammatory response in the hippocampus through regulation of microglial C5ar1 (show C5AR1 Antibodies) and C5ar2 expression
These results indicate that social stress-induced behavioral deficits are mediated partly by molecular adaptations in mPFC involving DeltaFosB and CCK (show CCK Antibodies) through cortical projections to distinct subcortical targets.
Fosb expression significantly increased corresponding to the DNA methylation (show HELLS Antibodies) level of the gene body in the arsenic-exposed group.
This study demonistrated that the fosB-null mouse is the first animal model to provide a genetic and molecular basis for the comorbidity between depression and epilepsy with abnormal neurogenesis, all of which are caused by loss of a single gene, fosB.
Data indicate that FosB increased silent synapses onto D1-expressing direct pathway medium spiny neurons (MSNs) in both the nucleus accumbens shell (Nac (show NLRP1 Antibodies)) and core, and decreased onto NAc (show NLRP1 Antibodies) shell, but not core, D2-expressing indirect pathway MSNs.
These findings indicate that FosB is essential for stress tolerance mediated by delta-FosB.
The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
FBJ murine osteosarcoma viral oncogene homolog B
, protein fosB
, G0/G1 switch regulatory protein 3
, activator protein 1
, FBJ osteosarcoma viral oncogene isoform deltaFosb-2