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Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. Additionally we are shipping FBXL18 Antibodies (35) and FBXL18 Kits (12) and many more products for this protein.
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FBXL18 plays an oncogenic role through promoting lysine 63-linked ubiquitination of Akt (show AKT1 Proteins) in glioma.
Fbxl18 regulates apoptosis by mediating ubiquitin-dependent proteasomal degradation of the pro-apoptotic protein Fbxl7 (show FBXL7 Proteins) that may impact cellular processes involved in cell cycle progression.
Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\\\\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box/LRR-repeat protein 18
, F-box and leucine-rich repeat protein 18
, f-box/LRR-repeat protein 18-like