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FEV (ETS Oncogene Family) Proteins (FEV)

FEV belongs to the ETS transcription factor family. Additionally we are shipping FEV (ETS Oncogene Family) Antibodies (11) and FEV (ETS Oncogene Family) Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FEV 54738 Q99581
FEV 260298 Q8QZW2
FEV 246271 O70132
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Top FEV (ETS Oncogene Family) Proteins at

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

FEV Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

Rat (Rattus)

More Proteins for FEV (ETS Oncogene Family) (FEV) Interaction Partners

Human FEV (ETS Oncogene Family) (FEV) interaction partners

  1. novel evidence for the role of Pet-1 in human amygdala threat processing extends literature demonstrating the influence of genetic variation in the serotonin system on emotional regulation

  2. Fev-ERK signaling is essential for hemogenic endothelium-based hematopoietic stem cell development.

  3. our data argue against an exclusive role of FEV in the adult human brain serotonergic system and genetic analyses did not suggest that FEV variation adds to the genetic liability towards affective disorders

  4. FEV identifies serotonin-producing cells in normal and neoplastic small intestine.

  5. Serotonin-related FEV gene variant in the sudden infant death syndrome is a common polymorphism in the African-American population.

  6. FEV acts as a transcriptional repressor through its DNA-binding ETS (show ETS1 Proteins) domain and alanine-rich domain.

  7. We showed that fev is exclusively expressed in the midline part of the human brainstem containing raphe nuclei, which also specifically expressed 5-HT (show DDC Proteins) transporter (sert (show SLC6A4 Proteins)) and tryptophan hydroxylase (tph (show TPH1 Proteins)), two markers of the 5-HT (show DDC Proteins) neurotransmitter system.

  8. Analysis of transgene expression in Pet-1 null mice indicates that Pet-1 is required to maintain the activity of the Pet-1 enhancer region in a subset of serotonin (5-HT (show DDC Proteins)) neurons.

  9. Variation in FEV gene observed exclusively in a subset of African American sudden infant death syndrome cases may help explain the observed abnormalities of this system in some SIDS (show IDS Proteins) cases and the ethnic disparity.

Mouse (Murine) FEV (ETS Oncogene Family) (FEV) interaction partners

  1. These results suggest a causal relationship between 5-HT1A (show HTR1A Proteins) and Pet1, and reveal a potential mechanism by which 5-HT1A (show HTR1A Proteins)-Pet1 autoregulatory loop is maintained by serotonin.

  2. novel evidence for the role of Pet-1 in fear processing and dendritic organization of amygdala neurons

  3. Pet1-dependent and Pet1-resistant 5-serotonin (5-HT (show DDC Proteins)) neurons target different brain centers that might delineate the anatomical basis for a dual serotonergic control on stress responses.

  4. The data of this study indicated that, in addition to transcriptional regulation by Pet-1 in raphe neurons, 5-HT1A receptor (show CC2D1A Proteins) expression is regulated indirectly by alterations in 5-HT (show DDC Proteins) neurotransmission in a region-specific manner

  5. This study indicated that Pet-1 is required across the lifespan of the mouse and that behavioral pathogenesis can result from both developmental and adult-onset alterations in serotonergic transcription.

  6. Pet-1(-/-) neonates are probably not hypoxic from respiratory dysfunction until P14 (show PCOLCE Proteins)-15; neither apnea-related hypoxia nor greater hypopnea contribute to the enhanced bradycardias of Pet-1 and there may be enhanced temperature reflex in hyperthermia

  7. expressed in central serotonergic (5-hydroxytryptaminergic) neurons located in the mes (show PTCH1 Proteins)-/metencephalic raphe nuclei from E11 (show PDPN Proteins) on until adulthood

  8. Pet-1 is a critical determinant of 5-HT (show DDC Proteins) neuron identity and Pet-1-dependent program is involved in serotonergic modulation of behavior

  9. Ectopic expression of Lmx1b (show LMX1B Proteins) plus Pet-1 is able to induce formation of 5-HT (show DDC Proteins) cells in the most ventral spinal cord, where Nkx2.2 (show Nkx2-2 Proteins) is normally expressed. Combined expression of Lmx1b (show LMX1B Proteins), Pet-1, and Nkx2.2 (show Nkx2-2 Proteins), drives 5-HT (show DDC Proteins) differentiation in the dorsal spinal cord

  10. Our findings identify a direct transcriptional interaction between Gata-2 (show GATA2 Proteins) and FEV and a unique marker for new insight into FEV/Pet-1 function in 5-HT (show DDC Proteins) neuron development.

Zebrafish FEV (ETS Oncogene Family) (FEV) interaction partners

  1. Fev-ERK signaling is essential for hemogenic endothelium-based hematopoietic stem cell development.

  2. Spatiotemporal expression profile of the Ets-domain transcription factor-encoding gene pet1 in developing and adult zebrafish.

FEV (ETS Oncogene Family) (FEV) Protein Profile

Protein Summary

This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.

Gene names and symbols associated with FEV

  • FEV (ETS oncogene family) (FEV)
  • FEV (ETS oncogene family) (Fev)
  • FEV (ETS oncogene family) (fev)
  • FEV protein
  • HSRNAFEV protein
  • mPet-1 protein
  • Pet-1 protein
  • pet1 protein
  • zgc:158720 protein

Protein level used designations for FEV

protein FEV , FEV (ETS oncogene family) , PC12 ETS domain-containing transcription factor 1 , fifth Ewing variant protein , ETS-domain transcription factor Pet-1 , FEV (fifth Ewing variant) , PC12 ETS factor 1 , pheochromocytoma 12 ETS (E26 transformation-specific) , ETS domain transcription factor Pet-1 , pet-1 , ETS domain transcription factor , Pet-1 , protein Pet-1

524933 Bos taurus
701065 Macaca mulatta
742785 Pan troglodytes
54738 Homo sapiens
260298 Mus musculus
246271 Rattus norvegicus
791175 Danio rerio
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