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Transcription repressor. Additionally we are shipping FEZ Family Zinc Finger 1 Antibodies (45) and and many more products for this protein.
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SEZ6L (show SEZ6L Proteins), HISPPD1, FEZF1, SAMD11 (show SAMD11 Proteins) gene variants may be associated with autism spectrum disorder.
Fezf1 and Fezf2 (show FEZF2 Proteins) accomplish both independent and redundant functions across diverse tissue and cell types. [Review]
Mutations in FEZF1 cause Kallmann syndrome.
the aberrant expression of ZNF312b promotes gastric tumorigenesis through epigenetic modification of its promoter region and provides a molecular mechanism for ZNF312b expression to contribute to the progression of gastric cancer.
Study is the first to report that ZNF312b, a novel transcription factor, was associated with tumorigenicity of gastric cancer.
These results identify Fezf1 and Fezf2 (show FEZF2 Proteins) as important regulators of olfactory system development and sensory neuron identity.
Fezf1 and Fezf2 (show FEZF2 Proteins) control differentiation of neural stem cells by repressing Hes5 (show HES5 Proteins) and, in turn, by derepressing neurogenin 2 (show NEUROG2 Proteins) in the forebrain.
Fez (show FEZF2 Proteins) is involved in the axonal projection of olfactory sensory neurons.
These data indicate that Fez (show FEZF2 Proteins) and Fezl (show FEZF2 Proteins) repress the caudal diencephalon fate in the rostral diencephalon, and ZLI formation probably depends on Fez/Fezl (show FEZF2 Proteins)-mediated formation of diencephalon subdivisions.
These data indicate that Fezf1 is required for the penetration of olfactory axons through the CNS basal lamina before they innervate the olfactory bulb.
Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors (By similarity).
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, zinc finger protein 312B
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