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anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) Antibodies

The protein encoded by FKBP1A is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Additionally we are shipping FK506 Binding Protein 1A, 12kDa Proteins (24) and FK506 Binding Protein 1A, 12kDa Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FKBP1A 14225 P26883
FKBP1A 25639 Q62658
FKBP1A 2280 P62942
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Top anti-FK506 Binding Protein 1A, 12kDa Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB FKBP1A Antibody (C-term) (ABIN1882082) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. FKBP1A Antibody (C-term) (ABIN1882082) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), IP, WB Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$595.83
Details
Cow Rabbit Un-conjugated IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB FKBP1A monoclonal antibody (M01), clone 1E5-A12 Western Blot analysis of FKBP1A expression in HL-60 . Western Blot analysis of FKBP1A expression in transfected 293T cell line by FKBP1A monoclonal antibody (M01), clone 1E5-A12.Lane 1: FKBP1A transfected lysate(12 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 16 Days
$218.90
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FKBP1A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-FKBP1A. Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-FKBP1A mouse monoclonal antibody. (ABIN2453044, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated WB Western Blot analysis of FKBP1A expression in transfected 293T cell line by FKBP1A monoclonal antibody (M01), clone 1E5-A12. Lane 1: FKBP1A transfected lysate(12 KDa). Lane 2: Non-transfected lysate. FKBP1A monoclonal antibody (M01), clone 1E5-A12 Western Blot analysis of FKBP1A expression in HL-60. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

FKBP1A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Rat (Rattus)


Human , , ,
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Top referenced anti-FK506 Binding Protein 1A, 12kDa Antibodies

  1. Human Polyclonal FKBP1A Primary Antibody for EIA, IHC (p) - ABIN360055 : Gerard, Debyser, Desender, Baert, Brandt, Baekelandt, Engelborghs: FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T. in Journal of neurochemistry 2008 (PubMed)
    Show all 3 references for ABIN360055

  2. Human Polyclonal FKBP1A Primary Antibody for FACS, IHC (p) - ABIN1882082 : Shor, Zhang, Toral-Barza, Lucas, Abraham, Gibbons, Yu: A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis. in Cancer research 2008 (PubMed)
    Show all 2 references for ABIN1882082

  3. Human Monoclonal FKBP1A Primary Antibody for ELISA, WB - ABIN560904 : Sitaraman, Chatterjee: Protein-protein interactions: an application of Tus-Ter mediated protein microarray system. in Methods in molecular biology (Clifton, N.J.) 2011 (PubMed)

More Antibodies against FK506 Binding Protein 1A, 12kDa Interaction Partners

Silk Worm FK506 Binding Protein 1A, 12kDa (FKBP1A) interaction partners

  1. expression higher in the silk gland and gut (show GUSB Antibodies)

  2. A cDNA encoding the 12 kDa FKBP gene orthologue (FKBP12) in Bombyx mori was been isolated from both Bm-5 cultured cells and silk-gland tissue.

Mouse (Murine) FK506 Binding Protein 1A, 12kDa (FKBP1A) interaction partners

  1. We demonstrate that FKBP12 and its ligands impact multiple aspects of muscle function.

  2. Fkbp1a-mediated regulation of Notch1 (show NOTCH1 Antibodies) plays an important role in intercellular communication between endocardium and myocardium.

  3. FKBP12 is critically important in regulating trans-sarcolemmal ionic currents, predominately the voltage-gated Na+ current, I Na

  4. the impact of simulated ischemia and reperfusion on expression of the calcium handling proteins FKBP12 and FKBP12.6 (show FKBP1B Antibodies), and intracellular calcium dynamics was investigated.

  5. Data show that deletion of FKBP12 increased transforming growth factor-beta receptor activation and SMAD2 (show SMAD2 Antibodies)/3 signaling.

  6. FKBP12 is a critical regulator of I(Na) and is important for cardiac arrhythmogenic physiology

  7. a trimeric-interaction among calcineurin (show PPP3CA Antibodies), FKBP12, and RyR (show RYR1 Antibodies) is important for the regulation of the RyR (show RYR1 Antibodies) channel activity and may play an important role in the Ca(2 (show CA2 Antibodies)+) signaling of muscle contraction and relaxation

  8. FKBP12 binding to RyR1 (show RYR1 Antibodies) enhances the gain of skeletal muscle excitation-contraction coupling

  9. used systemic gene transfer in tumor-bearing mice to identify novel antiinvasive and antimetastatic functions for Fkbp8 (show FKBP8 Antibodies), and subsequently for Fkbp1a

  10. FKBP12 deficiency alters both orthograde and retrograde coupling between the L-type Ca2 (show CA2 Antibodies)+ channel and RyR1 (show RYR1 Antibodies) and the consequences of these changes depend on muscle type and activity

Human FK506 Binding Protein 1A, 12kDa (FKBP1A) interaction partners

  1. Findings indicate that mutant huntingtin (show HTT Antibodies) (mHTT) aggregates can be transformed into benign species by isomerase FKBP12.

  2. RyRs have been identified as important targets of FKBP12 and FKBP12.6 (show FKBP1B Antibodies), members of the immunophilin family

  3. How phosphorylation of RyR (show RYR1 Antibodies) affects channel activity and whether proteins such as the FK-506 binding proteins (FKBP12 and FKBP12.6 (show FKBP1B Antibodies)) are involved in heart failure

  4. Ultra-fast Shape Recognition with Atom Types--the discovery of novel bioactive small molecular scaffolds for FKBP12 and 11betaHSD1.

  5. Selectivity within the FKBP (show FKBP7 Antibodies) family, in particular selective inhibition of FKBP12 or FKBP51 (show FKBP4 Antibodies), is possible. FKBP51 (show FKBP4 Antibodies) is a pharmacologically tractable target for stress-related disorders.

  6. peptidyl prolyl cis-trans isomerase (show PPIL1 Antibodies) activity of FKBP12 probably plays a role in inhibition of receptor phosphorylation.

  7. FKBP12 inhibits RyR1 (show RYR1 Antibodies) and FKBP12 E31Q/D32N/W59F mutant activates RyR1 (show RYR1 Antibodies) in vitro.

  8. FKBP12 regulates the localization and processing of amyloid precursor protein (show APP Antibodies) in human cell lines.

  9. Enhanced plasticity in the active site of FKBP12.6 (show FKBP1B Antibodies) is likely to contribute to marked attenuation in the spatial extent of the residues that exhibit doubling of their amide resonances compared with those of the homologous FKBP12.

  10. the structural basis of the slow resonance doubling transition of FKBP12 and the more rapid conformational linebroadening transition in the 80's loop to gain insight into how these effects are propagated through the protein structure

Rabbit FK506 Binding Protein 1A, 12kDa (FKBP1A) interaction partners

  1. Data indicate that S107 increased FKBP12 binding to RyR1 (show RYR1 Antibodies) in sarcoplasmic reticulum vesicles in the presence of reduced glutathione and the NO-donor NOC12.

  2. A mutant with substitution at the sole cysteine residue of FKBP-12 (C23S) did not form dimers or trimers.

  3. phosphorylation and K201 acted similarly to change the conformation of RyR1 (show RYR1 Antibodies)/2 and regulate FKBP12/12.6 binding.

Xenopus laevis FK506 Binding Protein 1A, 12kDa (FKBP1A) interaction partners

  1. Stoichiometry of binding sites and FKBP (show FKBP7 Antibodies) exchange binding.

FK506 Binding Protein 1A, 12kDa (FKBP1A) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.

Gene names and symbols associated with FKBP1A

  • FK506-binding protein (Fkbp12) antibody
  • peptidyl-prolyl isomerase FKBP12 (FKBP12) antibody
  • FK506 binding protein 1Aa (fkbp1aa) antibody
  • FK506 binding protein 1A, 12kDa (FKBP1A) antibody
  • FK506-binding protein (LOC733041) antibody
  • FK506-binding protein (EHI_180160) antibody
  • fk506-binding protein (AaeL_AAEL010491) antibody
  • FK506-binding protein (Fkbp13) antibody
  • FK506 binding protein like (FKBPL) antibody
  • FK506 binding protein 1a (Fkbp1a) antibody
  • Peptidyl-prolyl cis-trans isomerase FKBP1A-like (fkbp1a) antibody
  • 12kDa antibody
  • ARABIDOPSIS THALIANA FK506-BINDING PROTEIN 12 antibody
  • ATFKBP12 antibody
  • Bmfkbp13 antibody
  • fj02g10 antibody
  • FK506-binding protein 12 antibody
  • Fkbp antibody
  • FKBP-1A antibody
  • FKBP-12 antibody
  • FKBP1 antibody
  • FKBP1A antibody
  • FKBP1B antibody
  • Fkbp2 antibody
  • FKBP12 antibody
  • FKBP12-T1 antibody
  • FKBP12-T2 antibody
  • IMMUNOPHILIN antibody
  • mFKBP1 antibody
  • mFKBP12 antibody
  • MSJ1.19 antibody
  • MSJ1_19 antibody
  • PKC12 antibody
  • PKCI2 antibody
  • PPIASE antibody
  • Rotamase antibody
  • wu:fj02g10 antibody
  • zgc:73373 antibody

Protein level used designations for FKBP1A

FK506-binding protein , FK506 binding protein 1A, 12kDa , peptidyl-prolyl cis-trans isomerase FKBP1A , fk506-binding protein , FK506-binding protein-like , 12 kDa FK506-binding protein , 12 kDa FKBP , FK506 Binding Protein12-T1 , FK506 binding protein12 , FK506 binding protein12-T2 , FK506-binding protein 1A , FKBP-12 , FKBP-1A , FKBP12-Exip3 , PPIase FKBP1A , calstabin-1 , immunophilin FKBP12 , rotamase , FK506 binding protein 2 (13 kDa) , FK506-binding protein 1 (12kD) , FK506-binding protein 1a , FK506-binding protein 1 , FK506-binding protein 12 , FK506-binding protein 1A (12kD) , FK506-binding protein, T-cell, 12-kD , calstabin 1 , protein kinase C inhibitor 2 , FK506 binding protein 1B, 12.6 kDa , Immunophilin FKBP12 , binding protein , FK 506-binding protein

GENE ID SPECIES
732917 Bombyx mori
836556 Arabidopsis thaliana
335335 Danio rerio
374233 Gallus gallus
539546 Bos taurus
608169 Canis lupus familiaris
733041 Bombyx mori
749347 Pan troglodytes
3408135 Entamoeba histolytica HM-1:IMSS
5573443 Aedes aegypti
100141467 Bombyx mori
100154784 Sus scrofa
14225 Mus musculus
25639 Rattus norvegicus
2280 Homo sapiens
614795 Bos taurus
100328942 Oryctolagus cuniculus
379069 Xenopus laevis
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