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FK506 Binding Protein 1B, 12.6 KDa (FKBP1B) ELISA Kits

The protein encoded by FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Additionally we are shipping FKBP1B Antibodies (29) and FKBP1B Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FKBP1B 14226 Q9Z2I2
Anti-Rat FKBP1B FKBP1B 58950 P97534
FKBP1B 2281 P68106
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Top FKBP1B ELISA Kits at antibodies-online.com

Showing 2 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 4.7 pg/ml 18.75-1200 pg/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 0.36 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details

More ELISA Kits for FKBP1B Interaction Partners

Mouse (Murine) FK506 Binding Protein 1B, 12.6 KDa (FKBP1B) interaction partners

  1. Calstabin2 as a key modulator of cardiac aging.

  2. Sirolimus-FKBP12.6 impairs endothelial barrier function by activation of protein kinase C-alpha (show PKCa ELISA Kits) and downstream disruption of the p120 (show CTNND1 ELISA Kits)-VE cadherin (show CDH5 ELISA Kits) interaction in vascular endothelium.

  3. genetic approaches confirm the role of FKBP12.6 in regulating cardiac ryanodine receptors

  4. the impact of simulated ischemia and reperfusion on expression of the calcium handling proteins FKBP12 (show FKBP1A ELISA Kits) and FKBP12.6, and intracellular calcium dynamics was investigated.

  5. Transcription factor CHF1/Hey2 (show HEY2 ELISA Kits) regulates EC coupling and heart failure in mice through regulation of FKBP12.6.

  6. Cardiac FKBP12.6 overexpression in the mouse blunts pressure overload-induced maladaptive left ventricular remodelling.

  7. FKBP12.6 removal enhanced, whereas RyR2 (show RYR2 ELISA Kits) gene deletion blocked the hypoxic increase in Ca(2 (show CA2 ELISA Kits)+)(i) in pulmonary artery smooth muscle cells.

  8. Characterize the kinetics of FKBP12 (show FKBP1A ELISA Kits)/12.6 binding to RyR2 (show RYR2 ELISA Kits) in ventricular myocytes and effects on calcium signaling.

  9. FKBP12.6(-/-) mice displayed hyperinsulinemia, & resistance to high fat diet-induced hyperglycemia, suggesting that FKBP12.6 plays an important role in insulin (show INS ELISA Kits) secretion & blood glucose control.

  10. During exercise, RyR2 (show RYR2 ELISA Kits) phosphorylation by protein kinase A dissociates FKBP12.6 from the channel, increasing Ca(2 (show CA2 ELISA Kits)+) release and cardiac contractility. FKBP12.6(-/-) mice showed exercise-induced arrhythmias.

Human FK506 Binding Protein 1B, 12.6 KDa (FKBP1B) interaction partners

  1. RyRs have been identified as important targets of FKBP12 and FKBP12.6, members of the immunophilin (show FKBP1A ELISA Kits) family

  2. How phosphorylation of RyR (show RYR1 ELISA Kits) affects channel activity and whether proteins such as the FK-506 binding proteins (FKBP12 and FKBP12.6) are involved in heart failure

  3. Sirolimus-FKBP12.6 impairs endothelial barrier function by activation of protein kinase C-alpha (show PKCa ELISA Kits) and downstream disruption of the p120 (show HNRNPU ELISA Kits)-VE cadherin (show CDH5 ELISA Kits) interaction in vascular endothelium.

  4. These data corroborate other studies suggesting that mutations in FKBP12 and FKBP12.6 genes are not commonly related to cardiac diseases.

  5. FKBP12.6-deficient mice with cardiac hypertrophy do not display exercise-induced arrhythmia and/or sudden cardiac death.

  6. analysis of the ryanodine receptor (show RYR3 ELISA Kits) FK506-binding protein (show FKBPL ELISA Kits) subunit

  7. Characterize the kinetics of FKBP12/12.6 binding to RyR2 (show RYR2 ELISA Kits) in ventricular myocytes and effects on calcium signaling.

  8. localization of binding site to the NH2-terminal domain of the cardiac Ca2+ release channel (show RYR2 ELISA Kits)

  9. Data show that VTSIP (show RYR2 ELISA Kits)- and ARVD2 (show RYR2 ELISA Kits)-associated point mutations influence positively and negatively, respectively, the binding of RyR2 (show RYR2 ELISA Kits) to its gating protein FKBP12.6.

  10. data demonstrate that defective regulation of ryanodine receptor 2 (show RYR2 ELISA Kits) causes altered cellular phenotype via profound perturbations in intracellular calcium signaling and highlight a key modulatory role of FK506 binding protein 12.6

Rabbit FK506 Binding Protein 1B, 12.6 KDa (FKBP1B) interaction partners

  1. phosphorylation and K201 acted similarly to change the conformation of RyR1/2 and regulate FKBP12/12.6 binding.

  2. Stoichiometry of binding sites and FKBP (show FKBP7 ELISA Kits) exchange binding.

FKBP1B Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.

Gene names and symbols associated with FKBP1B

  • FK506 binding protein 1B, 12.6 kDa (FKBP1B) antibody
  • FK506 binding protein 1B, 12.6 kDa (fkbp1b) antibody
  • FK506 binding protein 1B, 12.6 kDa (LOC100230320) antibody
  • FK506 binding protein 1b (Fkbp1b) antibody
  • FK506 binding protein 1B (Fkbp1b) antibody
  • 12.6kDa antibody
  • AW494148 antibody
  • calstabin2 antibody
  • DKFZp459K1429 antibody
  • FKBP1B antibody
  • FKBP1L antibody
  • FKBP12.6 antibody
  • MGC68829 antibody
  • OTK4 antibody
  • PKBP1L antibody
  • PPIase antibody

Protein level used designations for FKBP1B

FK506 binding protein 12.6 , peptidyl-prolyl cis-trans isomerase FKBP1B , FK506 binding protein 1B, 12.6 kDa , calstabin2 , 12.6 kDa FK506-binding protein , 12.6 kDa FKBP , FK506-binding protein 12.6 , FK506-binding protein 1B , FKBP-12.6 , FKBP-1B , PPIase FKBP1B , immunophilin FKBP12.6 , rotamase , calstabin-2 , calstabin 2 , h-FKBP-12 , Immunophilin FKBP12.6 , PPIase 1B , Rotamase 1B , peptidyl-prolyl cis-trans isomerase 1B , peptidyl-prolyl cis-trans isomerase; PPIase

GENE ID SPECIES
395254 Gallus gallus
399004 Xenopus laevis
612965 Canis lupus familiaris
741549 Pan troglodytes
100125114 Xenopus (Silurana) tropicalis
100173212 Pongo abelii
100230320 Taeniopygia guttata
14226 Mus musculus
58950 Rattus norvegicus
2281 Homo sapiens
785179 Bos taurus
100008888 Oryctolagus cuniculus
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