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anti-FK506 Binding Protein 1a (FKBP1A) Antibodies

The protein encoded by FKBP1A is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Additionally we are shipping FK506 Binding Protein 1a Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FKBP1A 14225 P26883
FKBP1A 25639 Q62658
FKBP1A 2280 P62942
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Top anti-FK506 Binding Protein 1a Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of FKBP12 on a SW-13 cell lysate (Human adrenal gland carcinoma, ATCC CCL-105). Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the mouse anti-FKBP12 antibody. Immunofluorescence staining of HS 766T cells (Human pancreatic carcinoma, ATCC HTB-134). 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of FKBP12 (arrow) using rabbit polyclonal FKBP12 Antibody (Center) (ABIN392172). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the FKBP12 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FKBP12 antibody (Center) (ABIN392172), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chemical Mouse Un-conjugated IHC (p), WB   0.1 mg Log in to see 5 to 6 Days
$271.43
Details
Human Rabbit Un-conjugated IP, IHC, WB Western blot analysis of FKBP12 expression in rat kidney tissue lysate. 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 11 to 13 Days
$385.00
Details
Human Mouse Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 200 μg Log in to see 9 to 11 Days
$407.00
Details
Human Rabbit Un-conjugated WB   200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   0.4 mL Log in to see 2 to 3 Days
$391.88
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit Biotin IHC, ELISA, WB   100 μg Log in to see 11 to 13 Days
$424.60
Details

FKBP1A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)


Human
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Top referenced anti-FK506 Binding Protein 1a Antibodies

  1. Chemical Monoclonal FKBP1A Primary Antibody for IHC (p), WB - ABIN967396 : Flanagan, Corthésy, Bram, Crabtree: Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. in Nature 1991 (PubMed)
    Show all 3 references for ABIN967396

  2. Chicken Monoclonal FKBP1A Primary Antibody for IF, IP - ABIN968189 : Chen, Liu, Massague: Mechanism of TGFbeta receptor inhibition by FKBP12. in The EMBO journal 1997 (PubMed)
    Show all 2 references for ABIN968189

More Antibodies against FK506 Binding Protein 1a Interaction Partners

Mouse (Murine) FK506 Binding Protein 1a (FKBP1A) interaction partners

  1. We demonstrate that FKBP12 and its ligands impact multiple aspects of muscle function.

  2. Fkbp1a-mediated regulation of Notch1 (show NOTCH1 Antibodies) plays an important role in intercellular communication between endocardium and myocardium.

  3. FKBP12 is critically important in regulating trans-sarcolemmal ionic currents, predominately the voltage-gated Na+ current, I Na

  4. the impact of simulated ischemia and reperfusion on expression of the calcium handling proteins FKBP12 and FKBP12.6 (show FKBP1B Antibodies), and intracellular calcium dynamics was investigated.

  5. Data show that deletion of FKBP12 increased transforming growth factor-beta receptor activation and SMAD2 (show SMAD2 Antibodies)/3 signaling.

  6. FKBP12 is a critical regulator of I(Na) and is important for cardiac arrhythmogenic physiology

  7. a trimeric-interaction among calcineurin (show PPP3CA Antibodies), FKBP12, and RyR (show RYR1 Antibodies) is important for the regulation of the RyR (show RYR1 Antibodies) channel activity and may play an important role in the Ca(2 (show CA2 Antibodies)+) signaling of muscle contraction and relaxation

  8. FKBP12 binding to RyR1 (show RYR1 Antibodies) enhances the gain of skeletal muscle excitation-contraction coupling

  9. used systemic gene transfer in tumor-bearing mice to identify novel antiinvasive and antimetastatic functions for Fkbp8 (show FKBP8 Antibodies), and subsequently for Fkbp1a

  10. FKBP12 deficiency alters both orthograde and retrograde coupling between the L-type Ca2 (show CA2 Antibodies)+ channel and RyR1 (show RYR1 Antibodies) and the consequences of these changes depend on muscle type and activity

Human FK506 Binding Protein 1a (FKBP1A) interaction partners

  1. Findings indicate that mutant huntingtin (show HTT Antibodies) (mHTT) aggregates can be transformed into benign species by isomerase FKBP12.

  2. RyRs have been identified as important targets of FKBP12 and FKBP12.6 (show FKBP1B Antibodies), members of the immunophilin family

  3. How phosphorylation of RyR (show RYR1 Antibodies) affects channel activity and whether proteins such as the FK-506 binding proteins (FKBP12 and FKBP12.6 (show FKBP1B Antibodies)) are involved in heart failure

  4. Ultra-fast Shape Recognition with Atom Types--the discovery of novel bioactive small molecular scaffolds for FKBP12 and 11betaHSD1.

  5. Selectivity within the FKBP (show FKBP7 Antibodies) family, in particular selective inhibition of FKBP12 or FKBP51 (show FKBP4 Antibodies), is possible. FKBP51 (show FKBP4 Antibodies) is a pharmacologically tractable target for stress-related disorders.

  6. peptidyl prolyl cis-trans isomerase (show PPIL1 Antibodies) activity of FKBP12 probably plays a role in inhibition of receptor phosphorylation.

  7. FKBP12 inhibits RyR1 (show RYR1 Antibodies) and FKBP12 E31Q/D32N/W59F mutant activates RyR1 (show RYR1 Antibodies) in vitro.

  8. FKBP12 regulates the localization and processing of amyloid precursor protein (show APP Antibodies) in human cell lines.

  9. Enhanced plasticity in the active site of FKBP12.6 (show FKBP1B Antibodies) is likely to contribute to marked attenuation in the spatial extent of the residues that exhibit doubling of their amide resonances compared with those of the homologous FKBP12.

  10. the structural basis of the slow resonance doubling transition of FKBP12 and the more rapid conformational linebroadening transition in the 80's loop to gain insight into how these effects are propagated through the protein structure

FK506 Binding Protein 1a (FKBP1A) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.

Gene names and symbols associated with FKBP1A

  • FK506 binding protein 1a (Fkbp1a) antibody
  • FK506 binding protein 1A, 12kDa (FKBP1A) antibody
  • FK506 binding protein 1A, 12kDa pseudogene 4 (FKBP1AP4) antibody
  • 12kDa antibody
  • Fkbp antibody
  • FKBP-1A antibody
  • FKBP-12 antibody
  • FKBP1 antibody
  • FKBP1P4 antibody
  • Fkbp2 antibody
  • FKBP12 antibody
  • FKBP12-T1 antibody
  • FKBP12-T2 antibody
  • mFKBP1 antibody
  • mFKBP12 antibody
  • PKC12 antibody
  • PKCI2 antibody
  • PPIASE antibody

Protein level used designations for FKBP1A

12 kDa FK506-binding protein , 12 kDa FKBP , FK506 Binding Protein12-T1 , FK506 binding protein12 , FK506 binding protein12-T2 , FK506-binding protein 1A , FKBP-12 , FKBP-1A , FKBP12-Exip3 , PPIase FKBP1A , calstabin-1 , immunophilin FKBP12 , peptidyl-prolyl cis-trans isomerase FKBP1A , rotamase , FK506 binding protein 2 (13 kDa) , FK506-binding protein 1 (12kD) , FK506-binding protein 1a , FK506-binding protein 1 , FK506-binding protein 12 , FK506-binding protein 1A (12kD) , FK506-binding protein, T-cell, 12-kD , calstabin 1 , protein kinase C inhibitor 2

GENE ID SPECIES
14225 Mus musculus
25639 Rattus norvegicus
2280 Homo sapiens
2285 Homo sapiens
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