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The protein encoded by FKBP5 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Additionally we are shipping FKBP5 Proteins (13) and FKBP5 Kits (9) and many more products for this protein.
Showing 10 out of 121 products:
Dog (Canine) Monoclonal FKBP5 Primary Antibody for ICC, IF - ABIN361795
Cheung-Flynn, Roberts, Riggs, Smith: C-terminal sequences outside the tetratricopeptide repeat domain of FKBP51 and FKBP52 cause differential binding to Hsp90. in The Journal of biological chemistry 2003
Show all 6 references for ABIN361795
Human Polyclonal FKBP5 Primary Antibody for IF, IHC (p) - ABIN515669
Romano, Staibano, Greco, Brunetti, Nappo, Ilardi, Martinelli, Sorrentino, Di Pace, Mascolo, Bisogni, Scalvenzi, Alfano, Romano: FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential. in Cell death & disease 2013
Show all 3 references for ABIN515669
Human Polyclonal FKBP5 Primary Antibody for ICC, IF - ABIN261155
Romano, DAngelillo, Staibano, Simeone, DArrigo, Ascierto, Scalvenzi, Mascolo, Ilardi, Merolla, Jovarauskaite, Romano: Immunomodulatory pathways regulate expression of a spliced FKBP51 isoform in lymphocytes of melanoma patients. in Pigment cell & melanoma research 2015
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Chicken Polyclonal FKBP5 Primary Antibody for IHC, WB - ABIN2785846
Lekman, Laje, Charney, Rush, Wilson, Sorant, Lipsky, Wisniewski, Manji, McMahon, Paddock: The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort. in Biological psychiatry 2008
Human Monoclonal FKBP5 Primary Antibody for ELISA, WB - ABIN560908
van Lierop, Alkema, Laskewitz, Dijkema, van der Maaden, Smit, Plate, Conti, Jans, Timmers, van Boeckel, Lusher, McGuire, van Schaik, de Vlieg, Smeets, Hofstra, Boots, van Duin, Ingelse, Schoonen et al.: Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index. ... in PLoS ONE 2012
findings show that miR (show MLXIP Antibodies)-511 is a functional regulator of FKBP5 and can contribute to neuronal differentiation.
FKBP51 (show FKBP4 Antibodies) positively controls cell motility by promoting RhoA (show RHOA Antibodies) and ROCK activation, thus revealing a novel role for FKBP51 (show FKBP4 Antibodies) in cytoskeletal rearrangement and cell migration and invasion.
Since increased DNA methylation (show HELLS Antibodies) in HSD11B2 (show HSD11B2 Antibodies) and FKBP5 are seen in a minority of bisulfite sequencing clones, these epigenetic changes, and functional consequences, may affect subpopulations of placental cells.
we propose tumor tissue expression of FKBP51 (show FKBP4 Antibodies) protein as a reliable prognostic marker for OSCC tumors.
These results suggest that the association between FKBP5 and alcohol consumption is conserved in both mice and humans.
Two FKBP5 polymorphisms (rs4713902-C and rs9470079-A) showed significant associations with BPD (show MOD(MDG4) Antibodies).
Genetic variants of FKBP5 may be associated with depressive and anxiety state via differential effects on amygdala and orbitofrontal region.
dysregulation of GR, MR, FKBP5, and PTGES3 (show PTGES3 Antibodies) in autistic spectrum disorder (ASD (show ARSD Antibodies)) and suggest a possible role of inflammation in altered GR function in ASD (show ARSD Antibodies).
FKBP5 rs1360780 TT genotype predisposes childhood abuse subjects to widespread structural changes in grey matter volume.
FKBP5 regulates glucocorticoid receptor (show NR3C1 Antibodies) activity and response to stress.
Findings indicate a role of FK506 binding protein 5 (FKBP5) in hypoxia-regulated adipogenesis.
important regulator of PPARgamma (show PPARG Antibodies) in white adipose tissue
FKBP5 might increase muscle mass through the enhancements of muscle protein synthesis and myotube differentiation as well as an inhibition of muscle protein degradation in mice
We discovered that the suggested psychiatric risk factor FK506 binding protein (show FKBPL Antibodies) 51 (FKBP51) increases phosphorylation of GSK3beta (show GSK3b Antibodies) at serine 9 (pGSK3beta(S9)).
Results suggest that regulation of Fkbp5 mRNA expression via DNA methylation (show HELLS Antibodies), and its subsequent regulation of glucocorticoid receptor (show NR3C1 Antibodies) sensitivity may be implicated in the molecular mechanisms of fear retention and extinciton
the abundance of BDNF (show BDNF Antibodies) positively correlated and phosphorylated DNMT1 (show DNMT1 Antibodies) inversely correlated with that of FKBP51 in cells
FKBP5 associates with BECN1 (show BECN1 Antibodies), changes its phosphorylation and protein levels and enhances markers of autophagy and autophagic flux
Aged animals display elevated FKBP51 levels, which contribute to impaired resiliency to depressive-like behaviors through impaired glucocorticoid signaling, a phenotype that is abrogated in FKBP5-/- mice.
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
FK506 binding protein 5
, FK506-binding protein 5
, PPIase FKBP5
, peptidyl-prolyl cis-trans isomerase FKBP5
, 51 kDa FK506-binding protein 5
, 51 kDa FKBP
, 54 kDa progesterone receptor-associated immunophilin
, FF1 antigen
, HSP90-binding immunophilin
, T-cell FK506-binding protein
, androgen-regulated protein 6
, peptidylprolyl cis-trans isomerase
, 51 kDa FK506-binding protein