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anti-FK506 Binding Protein 8, 38kDa (FKBP8) Antibodies

The protein encoded by FKBP8 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Additionally we are shipping FK506 Binding Protein 8, 38kDa Proteins (7) and FK506 Binding Protein 8, 38kDa Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FKBP8 14232 O35465
FKBP8 290652 Q3B7U9
FKBP8 23770 Q14318
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Top anti-FK506 Binding Protein 8, 38kDa Antibodies at antibodies-online.com

Showing 10 out of 107 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FKBP8 Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 25 μL Log in to see 6 to 8 Days
$253.00
Details
Cow Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB FKBP8 Antibody (Center) (ABIN652170) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the FKBP8 antibody detected the FKBP8 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using protein A purified anti-FKBP8 antibody shows detection of exogenous FKBP8 in 50 µg of HEK293T whole cell lysate (lane 1). The results of peptide competition are shown in lane 2 where no specific staining is noted after the antibody is first incubated for 1h with the immunizing peptide in 5% BLOTTO prior to reaction with the membrane. The membrane was probed with the primary antibody at a 1:1,000 dilution in 5% BLOTTO at 4° C, overnight. 25 μL Log in to see 2 to 3 Days
$135.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of FKBP-38 with mouse intestine tissue lysate (left lane) and Jurkat cell lysate (Right lane). 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using protein A purified anti-FKBP8 antibody shows detection of exogenous FKBP8 in 50 µg of HEK293T whole cell lysate (lane 1). The results of peptide competition are shown in lane 2 where no specific staining is noted after the antibody is first incubated for 1h with the immunizing peptide in 5% BLOTTO prior to reaction with the membrane. The membrane was probed with the primary antibody at a 1:1,000 dilution in 5% BLOTTO at 4° C, overnight. 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

FKBP8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-FK506 Binding Protein 8, 38kDa Antibodies

  1. Cow (Bovine) Polyclonal FKBP8 Primary Antibody for WB - ABIN2782773 : Okamoto, Omori, Kaname, Abe, Nishimura, Suzuki, Miyamura, Yoshimori, Moriishi, Matsuura: A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication. in Journal of virology 2008 (PubMed)

  2. Human Polyclonal FKBP8 Primary Antibody for EIA, WB - ABIN401052 : Portier, Taglialatela: Bcl-2 localized at the nuclear compartment induces apoptosis after transient overexpression. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against FK506 Binding Protein 8, 38kDa Interaction Partners

Mouse (Murine) FK506 Binding Protein 8, 38kDa (FKBP8) interaction partners

  1. Our findings thus indicate that the FKBP38-ANKMY2 (show ANKMY2 Antibodies) axis plays a key role in regulation of Shh (show SHH Antibodies) signaling in vivo.

  2. In pre-hearing time Fkbp8-specific signal was also observed in the tectorial membrane, whose alpha- and beta-Tectorin (show TECTB Antibodies) components show similar time-dependent expression of mRNA as Fkbp8.

  3. used systemic gene transfer in tumor-bearing mice to identify novel antiinvasive and antimetastatic functions for Fkbp8, and subsequently for Fkbp1a (show FKBP1A Antibodies).

  4. Results show that FKBP8 is an essential antagonist of sonic hedgehog (show SHH Antibodies) signaling in central nervous system development.

  5. FKBP38 functions to anchor the 26S proteasome (show Psmd4 Antibodies) at the organellar membrane

  6. Gene expression analysis of Fkbp8 mutants revealed a perturbation of expression of neural tube patterning genes, suggesting that endogenous FKBP8 activity establishes dorso-ventral patterning of the neural tube.

  7. Findings suggest that FKBP38 is required for neuroectodermal organization during neural tube formation as a result of its anti-apoptotic activity and regulation of neurite extension

  8. Disruption of FKBP8 function activates the Shh (show SHH Antibodies) signaling pathway cell-autonomously dependent on the Gli2 (show GLI2 Antibodies) transcription factor and kinesin-2 (show KIF2A Antibodies) subunit Kif3a (show KIF3A Antibodies), a component of the intraflagellar transport machinery used to generate cilia.

  9. Data indicate that PHD2 (show EGLN1 Antibodies) protein stability is regulated by a ubiquitin-independent proteasomal pathway involving FKBP38 as adaptor protein that mediates proteasomal interaction.

Human FK506 Binding Protein 8, 38kDa (FKBP8) interaction partners

  1. The information presented here provides important clues for understanding the catalytic activity of FKBP38, its regulation by the unique N-terminal extension, and the potential calcium- and calmodulin (show CALM1 Antibodies)-mediated activation of FKBP38.

  2. Overexpression of permanently active S100P (show S100P Antibodies) in Huh-7 cells inhibited the interaction of FKBP38 with Bcl-2 (show BCL2 Antibodies), resulting in the suppression of Bcl-2 (show BCL2 Antibodies) stability

  3. FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR (show CFTR Antibodies)) folding and stability

  4. The derived structure model of the complex between Bcl-2 (show BCL2 Antibodies) and the FKBP38 catalytic domain features both electrostatic and hydrophobic intermolecular contacts and provides a rationale for the regulation of the FKBP38/Bcl-2 (show BCL2 Antibodies) interaction by Ca(2 (show CA2 Antibodies)+).

  5. Data support a dual role for FKBP38 in regulating CFTR (show CFTR Antibodies) synthesis and post-translational folding.

  6. a dual mechanism for PA activation of mTORC1: PA displaces FKBP38 from mTOR (show FRAP1 Antibodies) and allosterically stimulates the catalytic activity of mTORC1.

  7. this charge-sensitive site in the FKBP (show FKBP7 Antibodies) domain participates in the regulation of FKBP38 function by enabling electrostatic interactions with ligand proteins and/or salt ions such as Ca(2 (show CA2 Antibodies)+)

  8. These results demonstrate that FKBP38 is a novel regulator of the oncogenic protein PRL-3 abundance and that alteration in the stability of PRL-3 can have a dramatic impact on cell proliferation.

  9. novel insights into the structural arrangement of FKBP38/calmodulin (show CALM1 Antibodies) complex

  10. FKBP38 is a key player in regulating the function of Bcl-2 (show BCL2 Antibodies) by antagonizing caspase (show CASP3 Antibodies)-dependent degradation through the direct interaction with the flexible loop domain of Bcl-2 (show BCL2 Antibodies), which contains the caspase (show CASP3 Antibodies) cleavage site

FK506 Binding Protein 8, 38kDa (FKBP8) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.

Gene names and symbols associated with FKBP8

  • FK506 binding protein 8, 38kDa (FKBP8) antibody
  • FK506 binding protein 8, 38kDa (fkbp8) antibody
  • FK506-binding protein 8 (fkbp8) antibody
  • FK506 binding protein 8 (Fkbp8) antibody
  • FK506 binding protein 8 (fkbp8) antibody
  • 38kDa antibody
  • FKBP-8 antibody
  • FKBP-38 antibody
  • fkbp8 antibody
  • FKBP38 antibody
  • FKBPr38 antibody
  • zgc:77672 antibody

Protein level used designations for FKBP8

peptidyl-prolyl cis-trans isomerase FKBP8 , FK506 binding protein 8, 38kDa , peptidyl-prolyl cis-trans isomerase FKBP8-like , FK506-binding protein 8 , 38 kDa FK506-binding protein , 38 kDa FKBP , FK506-binding protein 38 , FKBPR38 , PPIase FKBP8 , mFKBP38 , rotamase , FK506-binding protein 8 (38kD) , FKBP-38 , FKBP-8 , hFKBP38

GENE ID SPECIES
420123 Gallus gallus
455862 Pan troglodytes
100145724 Xenopus (Silurana) tropicalis
100443356 Pongo abelii
100194916 Salmo salar
14232 Mus musculus
290652 Rattus norvegicus
393858 Danio rerio
23770 Homo sapiens
484819 Canis lupus familiaris
512356 Bos taurus
495188 Xenopus laevis
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