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Stimulates the proliferation of early hematopoietic cells by activating FLT3. Additionally we are shipping FMS-Like tyrosine Kinase 3 Ligand Kits (24) and FMS-Like tyrosine Kinase 3 Ligand Antibodies (4) and many more products for this protein.
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may be mediated by Flt3L (show FLT3LG Proteins)- and MMP-9 (show MMP9 Proteins)-dependent mobilization of dendritic cells
Bone marrow-derived CD117+ hematopoietic progenitor cells differentiate into thymic dendritic cells in the fetal thymus organ culture system in the presence of Flt3L (show FLT3LG Proteins).
Flt3L (show FLT3LG Proteins) significantly contributes to innate lymphoid cells and Peyer's patches development by targeting lymphoid progenitor cells during fetal and adult life.
unlike G-CSF (show CSF3 Proteins), Flt3 (show FLT3 Proteins)-L had an indirect effect on EI macrophages, as it was not detected at the surface of EI macrophages or erythroid progenitors.
Study showed shown Flt3L (show FLT3LG Proteins)-dependent accumulation of a population of DNGR-1(CLEC9A (show CLEC9A Proteins))-EGFP+ CD45h CD11blow MHCII+ myeloid cells in the brain
Data indicate that Flt3 ligand (show FLT3LG Proteins) knockout (Flt3L (show FLT3LG Proteins)-/-) mice are unable to control infection with Toxoplasma gondii.
inhibition of the calcineurin (show PPP3CA Proteins)-nuclear factor of activated T cells pathway enhances the proliferation of granulocyte-monocyte progenitors both in vitro and in vivo
The Cx3cr1 (show CX3CR1 Proteins)(gfp/+)Flt3L (show FLT3LG Proteins)(-/-) reporter mouse model represents a powerful tool to visualize monocyte activities in bone marrow.
Flt3L (show FLT3LG Proteins)(-/-) mice showed a marked decrease in clinical arthritis scores and incidence of arthritis in both acute and chronic phases of CIA (show NCOA5 Proteins) compared with WT mice. Moreover, decreased synovial inflammation and joint destruction was observed.
Flt3L (show FLT3LG Proteins) enhances global T cell and humoral immunity as well as both the numbers and antigen capture capacity of migratory dendritic cells and classical lymphoid-resident dendritic cells
Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
, fms-related tyrosine kinase 3 ligand
, fms-like tyrosine kinase 3 ligand