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FSHD Region Gene 1 (FRG1) ELISA Kits

FRG1 maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). Additionally we are shipping FSHD Region Gene 1 Antibodies (70) and FSHD Region Gene 1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat FRG1 FRG1 361156  
Anti-Human FRG1 FRG1 2483 Q14331
Anti-Mouse FRG1 FRG1 14300 P97376
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More ELISA Kits for FSHD Region Gene 1 Interaction Partners

Human FSHD Region Gene 1 (FRG1) interaction partners

  1. Our results demonstrate that FRG1 is a direct DUX4 transcriptional target uncovering a novel regulatory circuit contributing to Facioscapulohumeral muscular dystrophy.

  2. FRG1 mice overexpressing FHL1 (show FHL1 ELISA Kits) showed an improvement in the dystrophic phenotype

  3. This study suggests a novel role of FRG1 as epigenetic regulator of muscle differentiation and indicates that Suv4-20h1 (show SUV420H1 ELISA Kits) has a gene-specific function in myogenesis.

  4. depressed myoblast proliferation may contribute to the pathology of mice overexpressing FRG1 and may play a part in facioscapulohumeral muscular dystrophy

  5. These data provide the first biochemical activities (actin binding and RNA binding) for human FRG1 and the characterization of the endogenous human FRG1, together indicating that FRG1 is involved in multiple aspects of RNA biogenesis.

  6. in muscle FRG1 is a developmentally regulated sarcomeric protein suggesting FRG1 may perform a muscle-specific (show EIF3K ELISA Kits) function

  7. FRG1 transgenic mice develop a muscular dystrophy with features characteristic of the human disease; by contrast, FRG2 and ANT1 (show SLC25A4 ELISA Kits) transgenic mice seem normal

  8. differently from normal myoblasts, the 4qA/B marker interacted directly with the promoters of the FRG1 and ANT1 (show SLC25A4 ELISA Kits) genes in Facio-Scapulo-Humeral Dystrophy cells

  9. Data show that frg1 is expressed in and essential for the development of the tadpole musculature, and suggest that maintenance of normal FRG1 levels is critical for proper muscle development in frogs and humans.

  10. study compared chromatin structure & tridimensional interaction of the D4Z4 array and FRG1 gene promoter, and FRG1 expression, in control and FSHD cells

Mouse (Murine) FSHD Region Gene 1 (FRG1) interaction partners

  1. Mouse Frg1 genomic area lacks DUX4 binding sites and DUX4 is unable to activate the endogenous mouse Frg1 gene providing a possible explanation for the lack of muscle phenotype in DUX4 transgenic mice.

  2. This study suggests a novel role of FRG1 as epigenetic regulator of muscle differentiation and indicates that Suv4-20h1 (show SUV420H1 ELISA Kits) has a gene-specific function in myogenesis.

  3. On the basis of these results, it was proposed that aberrant fTnT represents a biological marker of muscle phenotype severity and disease progression.

  4. our results suggest that a component of FSHD pathogenesis may arise by over-expression of FRG1, reducing Rbfox1 (show A2BP1 ELISA Kits) levels and leading to aberrant expression of an altered Calpain 3 (show CAPN3 ELISA Kits) protein through dysregulated splicing

FSHD Region Gene 1 (FRG1) Antigen Profile

Antigen Summary

This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus.

Gene names and symbols associated with FSHD Region Gene 1 (FRG1) ELISA Kits

  • FSHD region gene 1-like (Frg1l) antibody
  • FSHD region gene 1 (FRG1) antibody
  • FSHD region gene 1 (frg1) antibody
  • FSHD region gene 1 (LOC100345738) antibody
  • FRG1 protein (frg1) antibody
  • FSHD region gene 1 (Frg1) antibody
  • frg1 antibody
  • FRG1A antibody
  • FSG1 antibody
  • MGC84293 antibody
  • MGC89908 antibody

Protein level used designations for FSHD Region Gene 1 (FRG1) ELISA Kits

FSHD region gene 1-like , FSHD region gene 1 , protein FRG1 , FSHD region gene 1 protein , facioscapulohumeral muscular dystrophy region gene-1

GENE ID SPECIES
361156 Rattus norvegicus
422726 Gallus gallus
444679 Xenopus laevis
448726 Xenopus (Silurana) tropicalis
482899 Canis lupus familiaris
698743 Macaca mulatta
738279 Pan troglodytes
100345738 Oryctolagus cuniculus
445937 Takifugu rubripes
2483 Homo sapiens
14300 Mus musculus
689484 Rattus norvegicus
512533 Bos taurus
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