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FXYD Domain Containing Ion Transport Regulator 3 Proteins (FXYD3)

FXYD3 belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. Additionally we are shipping FXYD Domain Containing Ion Transport Regulator 3 Antibodies (31) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FXYD3 5349 Q14802
FXYD3 17178 Q61835
Rat FXYD3 FXYD3 116831 P59645
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Top FXYD Domain Containing Ion Transport Regulator 3 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FXYD3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for FXYD Domain Containing Ion Transport Regulator 3 (FXYD3) Interaction Partners

Human FXYD Domain Containing Ion Transport Regulator 3 (FXYD3) interaction partners

  1. Suppression of FXYD3 in MCF-7.

  2. Study demonstrated that the expression of FXYD1 (show FXYD1 Proteins), FXYD3 and FXYD5 (show FXYD5 Proteins) is elevated in the lungs of Acute respiratory distress syndrome patients

  3. All three markers correlated significantly with regional lymph node metastasis: FXYD3 (p = 0.0110), S100A11 (show S100A11 Proteins) (p = 0.0071), and GSTM3 (show glutathione S-transferase mu 3 (brain) Proteins) (p = 0.0173) in colon cancer lymphatic metastasis.

  4. ExoS facilitates P. aeruginosa penetration through the intestinal epithelial barrier by binding to FXYD3 and thereby impairing the defense function of tight junctions against bacterial penetration.

  5. Up-regulated expression of FXYD-3 protein may be involved in tumourgenesis and invasion of gastric adenocarcinoma.

  6. FXYD3 expression is related to several biological variables including ras, p53 (show TP53 Proteins), legumain (show LGMN Proteins) and PCNA (show PCNA Proteins), and may be involved in the development of the relatively early stages of colorectal cancers

  7. Upregulation of FXYD3 is associated with glioma.

  8. inactivation of FXYD3 through a gene mutation or unknown mechanism could be one cause of the atypical shapes of cancer cells and play a potential role in the progression of lung cancer.

  9. Results indicate that the human MAT-8 gene contains the potential to serve as a prostate cancer expression marker and that MAT-8 plays an important role in cellular growth of prostate carcinomas.

  10. overexpression of FXYD3 in pancreatic cancer may contribute to the proliferative activity of this malignancy

Mouse (Murine) FXYD Domain Containing Ion Transport Regulator 3 (FXYD3) interaction partners

  1. Because gluco-incretin secretion depends on feeding the epigenetic regulation of Fxyd3 expression may link nutrition in early life to establishment of adult beta-cell glucose competence.

  2. Fxyd3 and Lgi4 transcripts potentially form double-stranded RNA molecules in many cell types in vivo, which may impact on their respective expression

  3. regulator of Na,K-ATPase (show ATP1A1 Proteins)

FXYD Domain Containing Ion Transport Regulator 3 (FXYD3) Protein Profile

Protein Summary

This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with FXYD3

  • FXYD domain containing ion transport regulator 3 (FXYD3)
  • FXYD domain-containing ion transport regulator 3 (Fxyd3)
  • FXYD3 protein
  • MAT-8 protein
  • Mat8 protein
  • PLML protein

Protein level used designations for FXYD3

FXYD domain containing ion transport regulator 3 , FXYD domain-containing ion transport regulator 3 , chloride conductance inducer protein Mat-8 , mammary tumor 8 kDa protein , phospholemman-like protein

GENE ID SPECIES
612671 Canis lupus familiaris
707346 Macaca mulatta
744576 Pan troglodytes
780807 Bos taurus
5349 Homo sapiens
397413 Sus scrofa
17178 Mus musculus
116831 Rattus norvegicus
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