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May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Additionally we are shipping FGD5 Proteins (3) and many more products for this protein.
Showing 10 out of 19 products:
Human Polyclonal FGD5 Primary Antibody for WB - ABIN531046
Kurogane, Miyata, Kubo, Nagamatsu, Kundu, Uemura, Ishida, Quertermous, Hirata, Rikitake: FGD5 mediates proangiogenic action of vascular endothelial growth factor in human vascular endothelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2012
Show all 2 Pubmed References
Human Polyclonal FGD5 Primary Antibody for ICC, IF - ABIN4311435
Ando, Fukuhara, Moriya, Obara, Nakahata, Mochizuki: Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization. in The Journal of cell biology 2013
FGD5 regulates VEGFR2 (show KDR Antibodies) retention in recycling endosomes and coupling to PI3 (show PI3 Antibodies) (phosphoinositide-3) kinase/mTORC2 (show CRTC2 Antibodies)-dependent cytoskeletal remodeling in endothelial cells.
FGD5 is a new prognostic marker in breast cancer, and increased copy number is associated with higher tumour proliferation and poorer long-term prognosis.
We provide the first report that pro-angiogenic genes PECAM1 (show PECAM1 Antibodies), PTGS1 (show PTGS1 Antibodies), FGD5, and MCAM (show MCAM Antibodies) may play a vital role in pathological dermal angiogenesis disorders of psoriasis.
FGD5 regulates endothelial adhesion, survival, and angiogenesis by modulating phosphatidylinositol 3-kinase signaling.
FGD5 inhibits neovascularization, indicated by in (show ARHGEF11 Antibodies)vitro tube-formation, aortic-ring, and coated-bead assays and by in vivo coated-bead plug assays and studies in the murine retina model.
Suggest that FGD5 regulates proangiogenic action of VEGF in vascular endothelial cells, including network formation, permeability, directional movement, and proliferation.
Fgd5 identifies hematopoietic stem cells in the murine bone marrow.
A new endothelial specific gene named FYVE, RhoGEF (show ARHGEF28 Antibodies), and PH domain-containing 5 (FGD5) plays a crucial role in vascular pruning in a murine model.
May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity).
FYVE, RhoGEF and PH domain-containing protein 5
, zinc finger FYVE domain-containing protein 23