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anti-Factor VIII (FVIII) Antibodies

Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa (By similarity).

list all antibodies Gene Name GeneID UniProt
Anti-Mouse FVIII FVIII 14069 Q06194
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More Antibodies against Factor VIII Interaction Partners

Mouse (Murine) Factor VIII (FVIII) interaction partners

  1. data demonstrate that infusion of platelets containing FVIII (show F8 Antibodies) triggers neither primary nor memory anti-FVIII (show F8 Antibodies) immune response in FVIII (show F8 Antibodies)(null) mice

  2. Both platelet-VWF (show VWF Antibodies) and plasma-VWF (show VWF Antibodies) are required for optimal platelet-derived FVIII (show F8 Antibodies) gene therapy for hemophilia A in the presence of inhibitors.

  3. These data support the investigation of FVIII (show F8 Antibodies) orthologs as treatment modalities in both the congenital and acquired FVIII (show F8 Antibodies) inhibitor settings.

  4. Activatable bioengineered FIX molecules with FVIII (show F8 Antibodies)-independent activity might be a promising tool for improving hemophilia A treatment, especially for patients with inhibitors.

  5. This study demonstrated that FVIIIa interacts with Low-density lipoprotein receptor-related protein 1 (show LRP1 Antibodies) cluster III.

  6. a fragment containing only approximately 20% of the VWF (show VWF Antibodies) sequence is sufficient to support FVIII (show F8 Antibodies) stability in vivo

  7. Endothelial cells from multiple, but not all, tissues contribute to the plasma FVIII (show F8 Antibodies) pool in the mouse.

  8. Endothelial cells are the predominant, and possibly exclusive, source of plasma FVIII (show F8 Antibodies).

  9. Micro-computed tomography analysis of distal tibia metaphyses also revealed for the first time a major impact of the FVIII (show F8 Antibodies)/thrombin (show F2 Antibodies)/PAR1 (show F2R Antibodies) axis on the dynamic bone structure, showing reduced bone.

  10. Findings indicate that improving protein trans-splicing by inter-chain disulfide bonding is a promising approach for increasing the efficacy of dual-vector based FVIII (show F8 Antibodies) gene transfer.

Pig (Porcine) Factor VIII (FVIII) interaction partners

  1. thrombin (show F2 Antibodies) stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (show UGDH Antibodies) and by receptor-mediated up-regulation of factor XIII (show UGDH Antibodies) synthesis

  2. cupredoxin-like A1 subdomains in fVIII (show F8 Antibodies) contain inter-species differences that are a result of selective pressure on the dissociation rate constant

Cow (Bovine) Factor VIII (FVIII) interaction partners

  1. Factor VIIIc (show COX7A2 Antibodies) is responsible for tissue invasion during tumor progression.

Factor VIII (FVIII) Antigen Profile

Protein Summary

Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa (By similarity).

Gene names and symbols associated with anti-Factor VIII (FVIII) Antibodies

  • coagulation factor VIII (F8) antibody
  • coagulation factor VIII, procoagulant component (F8) antibody
  • Cf-8 antibody
  • Cf8 antibody
  • FVIII antibody

Protein level used designations for anti-Factor VIII (FVIII) Antibodies

Factor VIII , procoagulant component , coagulation co-factor , coagulation factor VIII , coagulation factor VIII, procoagulant component (hemophilia A) , factor VIII

14069 Mus musculus
403875 Canis lupus familiaris
397339 Sus scrofa
100271720 Bos taurus
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