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Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa (By similarity). Additionally we are shipping Factor VIII Related Antigen Kits (6) and many more products for this protein.
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Factor VIIIc (show COX7A2 Antibodies) is responsible for tissue invasion during tumor progression.
thrombin (show F2 Antibodies) stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (show UGDH Antibodies) and by receptor-mediated up-regulation of factor XIII (show UGDH Antibodies) synthesis
cupredoxin-like A1 subdomains in fVIII (show F8 Antibodies) contain inter-species differences that are a result of selective pressure on the dissociation rate constant
data demonstrate that infusion of platelets containing FVIII (show F8 Antibodies) triggers neither primary nor memory anti-FVIII (show F8 Antibodies) immune response in FVIII (show F8 Antibodies)(null) mice
Both platelet-VWF (show VWF Antibodies) and plasma-VWF (show VWF Antibodies) are required for optimal platelet-derived FVIII (show F8 Antibodies) gene therapy for hemophilia A in the presence of inhibitors.
These data support the investigation of FVIII (show F8 Antibodies) orthologs as treatment modalities in both the congenital and acquired FVIII (show F8 Antibodies) inhibitor settings.
Activatable bioengineered FIX molecules with FVIII (show F8 Antibodies)-independent activity might be a promising tool for improving hemophilia A treatment, especially for patients with inhibitors.
This study demonstrated that FVIIIa interacts with Low-density lipoprotein receptor-related protein 1 (show LRP1 Antibodies) cluster III.
a fragment containing only approximately 20% of the VWF (show VWF Antibodies) sequence is sufficient to support FVIII (show F8 Antibodies) stability in vivo
Endothelial cells from multiple, but not all, tissues contribute to the plasma FVIII (show F8 Antibodies) pool in the mouse.
Endothelial cells are the predominant, and possibly exclusive, source of plasma FVIII (show F8 Antibodies).
Micro-computed tomography analysis of distal tibia metaphyses also revealed for the first time a major impact of the FVIII (show F8 Antibodies)/thrombin (show F2 Antibodies)/PAR1 (show F2R Antibodies) axis on the dynamic bone structure, showing reduced bone.
Findings indicate that improving protein trans-splicing by inter-chain disulfide bonding is a promising approach for increasing the efficacy of dual-vector based FVIII (show F8 Antibodies) gene transfer.
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa (By similarity).
coagulation factor VIII
, factor VIII
, coagulation co-factor
, coagulation factor VIII, procoagulant component (hemophilia A)
, procoagulant component
, Factor VIII