anti-Family with Sequence Similarity 175, Member B (FAM175B) Antibodies

Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. Additionally we are shipping Family with Sequence Similarity 175, Member B Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FAM175B 293570  
FAM175B 23172 Q15018
FAM175B 109359 Q3TCJ1
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Top anti-Family with Sequence Similarity 175, Member B Antibodies at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-KIAA0157 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IP, WB Western Blot and Immunoprecipitation: ABRO Antibody [ABIN253066] - Detection of Human ABRO by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- ABRO antibody ABIN253066 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. ABRO  was also immunoprecipitated by rabbit anti-ABRO antibody ABIN253067, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 seconds (B). 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IP, WB Western Blot: ABRO Antibody [ABIN253067] - Detection of Human ABRO by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-ABRO antibody ABIN253067 used for IP at 3 mcg/ lysate. ABRO was also immunoprecipitated by rabbit anti- ABRO antibody ABIN253066 which recognizes an upstream epitope.  Detection: Chemiluminescence with an exposure time of 3 seconds. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated WB KIAA0157 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$473.93
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of FAM175B expression in transfected 293T cell line by FAM175B MaxPab polyclonal antibody.Lane 1: KIAA0157 transfected lysate(34.21 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to KIAA0157 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 11 to 12 Days
$430.00
Details
Human Mouse Un-conjugated IF, WB   50 μg Log in to see 7 to 9 Days
$837.83
Details
Human Rabbit Un-conjugated IP   100 μg Log in to see 7 to 9 Days
$815.83
Details
Dog Rabbit Un-conjugated IP, WB   100 μL Log in to see 7 to 9 Days
$595.83
Details

FAM175B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus) ,


Human ,
,

Mouse (Murine) ,


Top referenced anti-Family with Sequence Similarity 175, Member B Antibodies

  1. Cow (Bovine) Polyclonal FAM175B Primary Antibody for WB - ABIN2786186 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

  2. Human Polyclonal FAM175B Primary Antibody for IP, WB - ABIN253066 : Brockmeyer, Paster, Pepper, Tan, Trudgian, McGowan, Fu, Gascoigne, Acuto, Salek: T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component. in The Journal of biological chemistry 2011 (PubMed)

More Antibodies against Family with Sequence Similarity 175, Member B Interaction Partners

Human Family with Sequence Similarity 175, Member B (FAM175B) interaction partners

  1. In late S/G2 (show STRN3 Antibodies) phase, the DNA damage-responsive E3 ligase RNF8 (show RNF8 Antibodies) conjugates K63-linked ubiquitin chains to tankyrase 1 (show TNKS Antibodies), while in G1 phase such ubiquitin chains are removed by BRISC, an ABRO1/BRCC36 (show BRCC3 Antibodies)-containing deubiquitinase complex.

  2. KIAA0157 allosterically activates a cognate deubiquitinating enzyme (DUB) partner and implicates super dimerization as a new regulatory mechanism underlying BRCC36 (show BRCC3 Antibodies) DUB activity.

  3. ABRO1 is a novel p53 (show TP53 Antibodies) regulator that plays an important role in tumor suppression and the DNA damage response

  4. Study identified Abro1 as a specific interactor of THAP5, a zinc finger transcription factor that is involved in G2/M control and apoptosis.

Mouse (Murine) Family with Sequence Similarity 175, Member B (FAM175B) interaction partners

  1. Data shows that the expression of Abro1 protein substantially increased (at least three-fold) in the hearts of mice that underwent MI/R compared to sham operated controls.

Family with Sequence Similarity 175, Member B (FAM175B) Antigen Profile

Protein Summary

Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. May act as a central scaffold protein that assembles the various components of the BRISC complex (By similarity).

Gene names and symbols associated with FAM175B

  • family with sequence similarity 175, member B (Fam175b) antibody
  • family with sequence similarity 175, member B (fam175b) antibody
  • family with sequence similarity 175, member B (FAM175B) antibody
  • AA589499 antibody
  • Abro1 antibody
  • AI853413 antibody
  • C430003P19Rik antibody
  • KIAA0157 antibody
  • MGC83343 antibody
  • RGD1308918 antibody

Protein level used designations for FAM175B

BRISC complex subunit Abro1 , Abraxas brother protein 1 , Protein FAM175B , family with sequence similarity 175, member B , abraxas brother 1 , abraxas brother protein 1

GENE ID SPECIES
293570 Rattus norvegicus
394764 Xenopus (Silurana) tropicalis
423954 Gallus gallus
447750 Xenopus laevis
23172 Homo sapiens
109359 Mus musculus
510233 Bos taurus
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