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Family with Sequence Similarity 3, Member B (FAM3B) ELISA Kits

Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. Additionally we are shipping Family with Sequence Similarity 3, Member B Antibodies (64) and Family with Sequence Similarity 3, Member B Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FAM3B 54097 P58499
FAM3B 52793 Q9D309
FAM3B 304050  
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Top Family with Sequence Similarity 3, Member B ELISA Kits at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.235 ng/mL 0.62-40 ng/mL 96 Tests Log in to see 9 to 11 Days
$810.53
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Mouse 0.124 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$833.68
Details
Mouse 0.1 ng/mL   96 Tests Log in to see 11 to 13 Days
$785.71
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Rabbit
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$785.71
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Pig
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$801.43
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Rat
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$785.71
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Goat
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$801.43
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Dog
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$801.43
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Guinea Pig
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$801.43
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Monkey
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$817.14
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More ELISA Kits for Family with Sequence Similarity 3, Member B Interaction Partners

Human Family with Sequence Similarity 3, Member B (FAM3B) interaction partners

  1. in-vitro and in-vivo glucose is a potent stimulator of the PANDER promoter within the liver and this response may be facilitated by ChREBP (show MLXIPL ELISA Kits).

  2. beta-cell-secreted PANDER regulated the hepatic insulin (show INS ELISA Kits) and lipogenenic signaling and impact overall glycemia.

  3. our studies demonstrated that silencing FAM3B promoted p53 (show TP53 ELISA Kits) phosphorylation and induced p53 (show TP53 ELISA Kits) accumulation by decreasing Mdm2 (show MDM2 ELISA Kits) expression, which resulted in apoptotic cell death.

  4. These results suggest that FAM3B-258 promotes colon cancer cell invasion and metastasis through upregulation of Slug (show SNAI2 ELISA Kits).

  5. Helices B and C and the second disulfide bond of PANDER are essential for PANDER-induced beta-cell death.

  6. PANDER is secreted from 2 types of pancreatic cells, glucose stimulates its secretion in beta cell and primary islets but not in alpha-cells, it is likely cosecreted with insulin (show INS ELISA Kits), and structure and conformation is vital for PANDER secretion.

Mouse (Murine) Family with Sequence Similarity 3, Member B (FAM3B) interaction partners

  1. in-vitro and in-vivo glucose is a potent stimulator of the PANDER promoter within the liver and this response may be facilitated by ChREBP (show MLXIPL ELISA Kits).

  2. F3MB(PANDER) decreases mice hepatic triglyceride and is associated with decreased DGAT1 (show DGAT1 ELISA Kits) expression

  3. X-ray crystal structure of the mouse FAM3B protein.

  4. these results demonstrated that the JNK (show MAPK8 ELISA Kits)-mediated signaling mechanism of palmitic acid -induced beta-cell apoptosis involves up-regulated expression of PANDER and activation of caspase-3 (show CASP3 ELISA Kits).

  5. Data suggest a new link between the endocrine and immune systems and provide useful information for further investigating the physiological functions of PANDER and its involvement in inflammation-related pancreatic disorders.

  6. Palmitic acid induces the expression of PANDER and the apoptosis of beta-TC3 cells while glucagon-like peptide-1 (show GCG ELISA Kits) counteracts the above effects through an activation of Akt (show AKT1 ELISA Kits) signaling.

  7. PANDER promotes lipogenesis and compromises insulin (show INS ELISA Kits) signaling in the liver by increasing FOXO1 (show FOXO1 ELISA Kits) activity.

  8. Findings further indicate PANDER impacts glycemic levels and may represent a potential but complicated therapeutic target.

  9. A paracrine/endocrine effect of insulin (show INS ELISA Kits) on Pander release and a potential glucose-regulatory role for Pander.

  10. we provide evidence that identifies PANDER as a regulator of hepatic glucose metabolism, where it amplifies hepatic cAMP and cAMP-response element-binding protein (show CREB ELISA Kits) signaling to induce gluconeogenic gene expression and glucose output.

Family with Sequence Similarity 3, Member B (FAM3B) Antigen Profile

Antigen Summary

Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. Present in insulin secretory granules and likely cosecreted with insulin.

Gene names and symbols associated with FAM3B

  • family with sequence similarity 3, member B (LOC100221253) antibody
  • family with sequence similarity 3, member B (FAM3B) antibody
  • family with sequence similarity 3, member B (Fam3b) antibody
  • 2-21 antibody
  • 9030624C24Rik antibody
  • C21orf11 antibody
  • C21orf76 antibody
  • D16Jhu19e antibody
  • ORF9 antibody
  • Pander antibody
  • RGD1311662 antibody

Protein level used designations for FAM3B

family with sequence similarity 3, member B , D21M16SJHU19e , cytokine-like protein 2-21 , pancreatic derived factor , pancreatic-derived factor , protein FAM3B

GENE ID SPECIES
100221253 Taeniopygia guttata
54097 Homo sapiens
52793 Mus musculus
514701 Bos taurus
478419 Canis lupus familiaris
418527 Gallus gallus
100517916 Sus scrofa
304050 Rattus norvegicus
101119956 Ovis aries
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