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FAM3C is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. Additionally we are shipping FAM3C Antibodies (50) and FAM3C Kits (2) and many more products for this protein.
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Human FAM3C Protein expressed in Escherichia coli (E. coli) - ABIN667961
Pilipenko, Reece, Choo, Greinwald: Genomic organization and expression analysis of the murine Fam3c gene. in Gene 2004
Show all 2 references for ABIN667961
FAM3C expression was dramatically increased in esophageal squamous cell carcinoma and might serve as a valuable prognostic indicator for esophageal squamous cell carcinoma patients after surgery
Altered subcellular ILEI localization strongly correlates with high tumor cell-associated uPAR (show PLAUR Proteins) protein expression.
Our findings indicate that cytoplasmic ILEI expression is a potential marker of EMT (show ITK Proteins) and tumour progression in colorectal cancer. ILEI is an independent predictive factor associated with poor prognosis in colorectal cancer.
ILEI could induce, as well as maintain, CD24 (show CD24 Proteins)(low)CD44 (show CD44 Proteins)(high) subpopulation in A549 cells treated with TGF-beta (show TGFB1 Proteins), which might explain its capability to induce metastatic progression.
At the FAM3C gene locus where rs7776725 was located, we identified several other SNPs (rs4727922, rs1803389, rs718766 and rs7793554) that were also associated with BMD (show BEST1 Proteins).
ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors.
Data show that FAM3C is decreased in the CSF (show CSF2 Proteins) of temporal lobe epilepsy patients.
TGF-beta (show TGFB1 Proteins) modulates the expression of Dab2 (show DAB2 Proteins) and ILEI mRNA required for epithelial-mesenchymal transdifferentiation by inducing phosphorylation of hnRNP E1 (show PCBP1 Proteins), resulting in its release from a structural, 33-nucleotide BAT (show BAAT Proteins) element in the 3'UTR of Dab2 (show DAB2 Proteins) and ILEI.
FAM3C orthologous protein, may be involved in cell differentiation and proliferation during inner ear embryogenesis
ILEI requires cooperation with oncogenic Ras to govern hepatocellular EMT (show ITK Proteins) through mechanisms involving PDGF-R/beta (show PDGFRB Proteins)-catenin (show CTNNB1 Proteins) and PDGF (show PDGFA Proteins)-R/Stat3 (show STAT3 Proteins) signaling.
This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells.
hypothetical protein LOC549860
, Protein FAM3C
, family with sequence similarity 3, member C
, protein FAM3C
, interleukin-like EMT inducer
, predicted osteoblast protein
, FAM3C-like protein