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Fanconi Anemia, Complementation Group B Proteins (FANCB)

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Additionally we are shipping Fanconi Anemia, Complementation Group B Antibodies (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FANCB 2187 Q8NB91
FANCB 237211 Q5XJY6
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Top Fanconi Anemia, Complementation Group B Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

FANCB Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Fanconi Anemia, Complementation Group B (FANCB) Interaction Partners

Human Fanconi Anemia, Complementation Group B (FANCB) interaction partners

  1. Loss-of-function FANCB (show BRCA2 Proteins) mutations result in a recognizable, multiple malformation phenotype in hemizygous males for which we propose clinical criteria to aid diagnosis.

  2. Inactivation of FancB (show BRCA2 Proteins) may play a role in the pathogenesis of sporadic HNSCC.

  3. Elevated serum FA-2 was associated with bony metastases from breast cancer.

  4. the protein defective in individuals with Fanconi anemia belonging to complementation group B is an essential component of the nuclear protein 'core complex' responsible for monoubiquitination of FANCD2

  5. summary of recent advances in the Fanconi anemia (show PALB2 Proteins)-BRCA network with emphasis on the new discovery of FAAP95 as the true FANCB (show BRCA2 Proteins) gene [review]

  6. Mutations in FANCB (show BRCA2 Proteins) are a cause of X linked VACTERL-H syndrome.

  7. Mus81 (show MUS81 Proteins) and FANCB (show BRCA2 Proteins) have different roles in repair of DNA damage during replication in human cells

  8. Our results rule out a major contribution of FANCB (show BRCA2 Proteins) to hereditary breast cancer.

Mouse (Murine) Fanconi Anemia, Complementation Group B (FANCB) interaction partners

  1. FANCB functions at critical stages of germ cell development and reveal a novel function of the FA pathway in the regulation of H3K9 methylation in the germline.

Fanconi Anemia, Complementation Group B (FANCB) Protein Profile

Protein Summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein.

Gene names and symbols associated with FANCB

  • Fanconi anemia, complementation group B (FANCB)
  • Fanconi anemia, complementation group B (Fancb)
  • BC022692 protein
  • FA2 protein
  • FAAP90 protein
  • FAAP95 protein
  • FAB protein
  • FACB protein

Protein level used designations for FANCB

Fanconi anemia group B protein , Fanconi anemia-associated polypeptide of 95 kDa , Fanconi anemia group B protein homolog

GENE ID SPECIES
2187 Homo sapiens
237211 Mus musculus
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