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Farnesyl Diphosphate Synthase (FDPS) ELISA Kits

FDPS encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. Additionally we are shipping FDPS Antibodies (94) and FDPS Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FDPS 2224 P14324
FDPS 83791 P05369
FDPS 110196 Q920E5
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Top FDPS ELISA Kits at antibodies-online.com

Showing 5 out of 12 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 0.057 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$800.00
Details
Human 28.3 pg/mL 62.5-4000 pg/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse
  96 Tests Log in to see 11 to 13 Days
$875.60
Details
Cow
  96 Tests Log in to see 11 to 13 Days
$1,029.60
Details
Chicken
  96 Tests Log in to see 11 to 13 Days
$1,095.60
Details

More ELISA Kits for FDPS Interaction Partners

Fruit Fly (Drosophila melanogaster) Farnesyl Diphosphate Synthase (FDPS) interaction partners

  1. mitochondrial targeting of FPS may be widespread among eukaryotes

  2. Farnesyl diphosphate synthase (FPPS) of the dipteran Drosophila melanogaster has been cloned and its catalytic properties have been assessed.

Human Farnesyl Diphosphate Synthase (FDPS) interaction partners

  1. These results are consistent with the previously proposed hypothesis that the allosteric pocket of human FPPS, located near the active site, plays a feed-back regulatory role for this enzyme.

  2. our study indicated that DR patients have higher VEGF levels than diabetic patients without retinopathy, and -2578A/C (rs699947) and +405C/G (rs2010963) may be important factors in determining serum VEGF levels.

  3. Results suggest that polymorphisms of the FDPS gene may influence the bone response to drugs targeting the mevalonate pathway, like statins.

  4. A co-crystal structure of human farnesyl pyrophosphate synthase in complex with a bisphosphonate and two molecules of inorganic phosphate.

  5. The results identify new classes of FPPS inhibitors, diterpenoids and sesquiterpenoids, that bind to the IPP (show IPP ELISA Kits) site and may be of interest as anticancer and antiinfective drug leads.

  6. These observations suggest that an increase in the expression of endogenous FPPS could confer at least partial resistance to the pharmacological effect of N-BP drugs such as ZOL in vivo

  7. LRP5 (show LRP5 ELISA Kits) and FDPS loci age-specifically affect skeletal traits in healthy fertile women.

  8. Data indicate compounds represent a new structural class of farnesyl pyrophosphate synthase (hFPPS) inhibitors and suggest a development of therapeutics.

  9. The iPA-driven modulation of FDPS can cause an enhancement of post-translational prenylation essential for the biological activity of key proteins in NK signaling and effector functions, such as Ras.

  10. FPPS was more highly expressed in prostate cancer vs. normal prostate tissue. The association of FPPS with established histopathological risk parameters and biochemical recurrence implicates a contribution of the mevalonate pathway to PC progression.

Mouse (Murine) Farnesyl Diphosphate Synthase (FDPS) interaction partners

  1. Farnesyl pyrophosphate synthase (FPPS) may function as a potent regulator in myocardial remodelling. The FPPS-regulated signalling pathway is relevant to the pathological changes in cardiac hypertrophy and heart failure.

  2. identified a single putative direct repeat 4 (DR4) LXR (show NR1H3 ELISA Kits) response element in the FPS (show FES ELISA Kits) promoter isolated from immortalized murine astrocyte P11 (show S100A10 ELISA Kits)-5 cells

FDPS Antigen Profile

Antigen Summary

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with FDPS

  • Farnesyl pyrophosphate synthase (Fpps) antibody
  • farnesyl diphosphate synthase (fdps) antibody
  • farnesyl pyrophosphate synthetase (MGG_08649) antibody
  • farnesyl pyrophosphate synthetase (TP03_0857) antibody
  • farnesyl pyrophosphate synthetase (Tb09.160.4300) antibody
  • farnesyl pyrophosphate synthetase (NCU01175) antibody
  • farnesyl pyrophosphate synthetase (BBOV_I000120) antibody
  • FDP synthase (fps) antibody
  • Farnesyl pyrophosphate synthetase (fpps) antibody
  • farnesyl diphosphate synthase (FDPS) antibody
  • farnesyl diphosphate synthase (Fdps) antibody
  • farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) (FDPS) antibody
  • farnesyl diphosphate synthetase (Fdps) antibody
  • farnesyl pyrophosphate synthase1 (fps1) antibody
  • (2E antibody
  • 16.m00760 antibody
  • 6030492I17Rik antibody
  • Ac2-125 antibody
  • AI256750 antibody
  • CG12389 antibody
  • DDBDRAFT_0206220 antibody
  • DDBDRAFT_0215017 antibody
  • DDB_0206220 antibody
  • DDB_0215017 antibody
  • Dmel\\CG12389 antibody
  • DmFPPS antibody
  • DmFPPSase antibody
  • DmFPS antibody
  • Fdpsl1 antibody
  • FPPS antibody
  • fps antibody
  • l(2)k06103 antibody
  • mKIAA1293 antibody
  • NCU01175.1 antibody
  • v(2)k03514 antibody

Protein level used designations for FDPS

farnesyl pyrophosphate synthase , CG12389-PA , Fpps-PA , farnesyl diphosphate synthase , farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) , farnesyl pyrophosphate synthetase , Farnesyl pyrophosphate synthetase , (2E,6E)-farnesyl diphosphate synthase , FPP synthase , FPP synthetase , dimethylallyltranstransferase , farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase , geranyltranstransferase , CR 39 , cholesterol-regulated 39 kDa protein , farnesyl diphosphate synthetase , testis-specific farnesyl pyrophosphate synthetase , FPS , 6E)-farnesyl diphosphate synthase , FPPS , GRMZM2G168681 , PCO074380 , PCO074380(592) , PCO074380_ov , PCO074380b , QBB18h08 , geranylgeranyl-diphosphate synthase , gnp_QBB18h08b , gpm430b , prenyltransferase

GENE ID SPECIES
36209 Drosophila melanogaster
548584 Xenopus (Silurana) tropicalis
735190 Xenopus laevis
2678891 Magnaporthe oryzae 70-15
3499793 Theileria parva strain Muguga
3660082 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3877737 Neurospora crassa OR74A
5476865 Babesia bovis T2Bo
8621722 Dictyostelium discoideum AX4
100195349 Salmo salar
2224 Homo sapiens
83791 Rattus norvegicus
281156 Bos taurus
480129 Canis lupus familiaris
425061 Gallus gallus
110196 Mus musculus
541903 Zea mays
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