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Fas Apoptotic Inhibitory Molecule Proteins (FAIM)

The protein encoded by FAIM protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Additionally we are shipping FAIM Antibodies (92) and FAIM Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FAIM 55179 Q9NVQ4
FAIM 23873 Q9WUD8
FAIM 140930 Q8R5H8
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Top FAIM Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,489.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,489.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FAIM Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Fas Apoptotic Inhibitory Molecule (FAIM) Interaction Partners

Human Fas Apoptotic Inhibitory Molecule (FAIM) interaction partners

  1. FAIM modulates IGF-1 (show IGF1 Proteins)-induced Akt (show AKT1 Proteins) activation and IRF4 (show IRF4 Proteins) expression and has a role in multiple myeloma cell survival

  2. FAIM (1-90) was crystallized and diffracted to a resolution of 2.5 A; the crystal belonged to space group P3(1), with unit-cell parameters a=b=58.02, c=71.11 A, alpha=beta=90, gamma=120 degrees.

  3. Human keratinocytes were transfected with either Flip, Faim, or Lifeguard (LFG (show FAIM2 Proteins)). Our results suggest that heterotopic expression of antiapoptotic proteins can induce the resistance of keratinocytes to a major mechanism of rejection.

  4. Expression of the long form of Fas apoptotic inhibitory molecule (FAIML) results in the protection of neurons from the cytotoxic actions of death ligands.

  5. FAIM acts to specifically enhance CD40 (show CD40 Proteins) signaling for NF-kappaB (show NFKB1 Proteins) activation, IRF-4 (show IRF4 Proteins) expression, and BCL-6 (show BCL6 Proteins) down-regulation in vitro, but has no effect on its own

Mouse (Murine) Fas Apoptotic Inhibitory Molecule (FAIM) interaction partners

  1. defined a TCR-induced FAIM/Akt (show AKT1 Proteins)/Nur77 (show NR4A1 Proteins) signaling axis that is critical for modulating the apoptosis of developing thymocytes

  2. The NMR solution structure of the C-terminal domain of murine FAIM is solved in isolation and revealed to be a novel protein fold, a noninterleaved seven-stranded beta-sandwich.

  3. FAIM plays a novel role in modulating Fas (show FAS Proteins)-mediated apoptosis and acts through influencing the expression of c-FLIP (show CFLAR Proteins) and regulating the physical binding of caspase-8 (show CASP8 Proteins) to Fas (show FAS Proteins).

  4. FAIM is expressed in germinal center B cells, enhances interferon (show IFNA Proteins) regulatory factor (IRF)4 (show IRF4 Proteins) expression, and is in turn positively regulated through IRF4 (show IRF4 Proteins) in a positive reinforcing (i.e., feed-forward) system.

FAIM Protein Profile

Protein Summary

The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with FAIM

  • Fas apoptotic inhibitory molecule (FAIM)
  • Fas apoptotic inhibitory molecule (faim)
  • Fas apoptotic inhibitory molecule (Tsp_00038)
  • Fas apoptotic inhibitory molecule (Faim)
  • predicted gene 6432 (Gm6432)
  • EG623459 protein
  • faim protein
  • FAIM1 protein

Protein level used designations for FAIM

Fas apoptotic inhibitory molecule , fas apoptotic inhibitory molecule 1 , Fas apoptosis inhibitory molecule 1 , fas apoptotic inhibitory molecule 1-like

GENE ID SPECIES
460729 Pan troglodytes
716216 Macaca mulatta
496608 Xenopus (Silurana) tropicalis
424270 Gallus gallus
10901294 Trichinella spiralis
55179 Homo sapiens
485687 Canis lupus familiaris
23873 Mus musculus
140930 Rattus norvegicus
734582 Xenopus laevis
616795 Bos taurus
100568454 Sus scrofa
623459 Mus musculus
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