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may mediate development and maintenance of the nervous system [RGD, Feb 2006].. Additionally we are shipping FAIM2 Antibodies (64) and many more products for this protein.
Showing 4 out of 4 products:
Human FAIM2 Protein expressed in Wheat germ - ABIN1353388
Müller, Maurer, Reimers, Vogt, Bucan: TRIM21, a negative modulator of LFG in breast carcinoma MDA-MB-231 cells in vitro. in International journal of oncology 2015
The interaction of TRIM21 (show TRIM21 Proteins) and LFG was analyzed by co-immunoprecipitation. To examine changes in regulatory processes, western blot analyses, real-time PCR, activity of apoptotic process and flow cytometric analyses were carried out.
There are significant differences in the associations of the FAIM2 promoter methylation with sedentary behaviour and physical activity between obese and lean children.
Methylation levels of the FAIM2 promoter are significantly associated with obesity and are independently associated with dyslipidaemia and its components in Chinese children.
Low KRT13 (show KRT13 Proteins) mRNA expression is associated with oral squamous cell carcinoma.
These results suggest that the TMBIM family has comparable functions in the maintenance of intracellular Ca(2 (show CA2 Proteins)) homeostasis in a wide variety of tissues
Results indicated that FAIM2 beta-isoform is strongly expressed in breast tumour tissues. Fas (show FAS Proteins) sensitivity was reduced in the MCF10A breast cells expressing the FAIM2 beta-isoform.
This study highlighted the importance of two candidate genes, SH2B1 (show SH2B1 Proteins) and FAIM2, in the risk of overweight/obesity.
A polymorphism in FAIM2 is associated with higher myocardial infarction risk in type-2 diabetes mellitus subjects.
The rs7138803 variant of FAIM2 was found to exert no effect on obesity in a Chinese Han population.
Faim2 is physiologically expressed in brain in bacterial meningitis.
LFG plays a role in protecting T cells from apoptosis during antiviral immune response.
Data suggest Faim2/LFG (lifeguard protein) protects against FasL-/Fas ligand (show FASL Proteins)-induced apoptosis by down-regulating calcium release from endoplasmic reticulum in cortical neurons.
In Faim2-deficient mice, there was increased hippocampal cell death during acute bacterial meningitis.
Expression of Faim2 is triggered, at least in part, by Fas-receptor (show FAS Proteins) activation and subsequent ERK (show EPHB2 Proteins) signaling.
mechanism of action of LFG as an inhibitor of the Fas (show FAS Proteins) pathway and evidence of the neuroprotective role of LFG in cerebellar granule neurons and Purkinje cells in an organotypic cerebellar culture system
This study demonistrated that lack of Faim2 caused an increase in susceptibility to combined oxygen-glucose deprivation in primary neurons as well as in caspase (show CASP3 Proteins)-associated cell death, stroke volume, and neurological impairment after cerebral ischemia.
LFG is an endogenous inhibitor of FasL (show FASL Proteins)-mediated neuronal death detected in lipid rafts microdomains, and it mediates the FasL (show FASL Proteins) resistance of CNS differentiated neurons
may mediate development and maintenance of the nervous system
Fas apoptotic inhibitory molecule 2
, protein lifeguard 2
, fas apoptotic inhibitory molecule 2
, neuromembrane protein 35
, neural membrane protein 35
, transmembrane BAX inhibitor motif-containing protein 2