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anti-Fascin Homolog 1, Actin Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) Antibodies

Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio.

list all antibodies Gene Name GeneID UniProt
FSCN1 14086 Q61553
FSCN1    
FSCN1    
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Top anti-Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Antibodies at antibodies-online.com

Showing 10 out of 183 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of Fascin Antibody (Center) (ABIN390697) in Y79 cell line lysates (35 µg/lane). Fascin (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma with Fascin Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Dog Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-phospho-FSCN1(Ser39) Polyclonal Antibody, Unconjugated (ABIN673011) at 1:200 followed by conjugation to the secondary antibody and DAB staining Image kindly submitted by Dr. Magdalena Krol. Control canine mammary tumor cells, tumor cells cultured in macrophage-conditioned medium, and co-cultured with macrophages were seeded on Lab-Tek slides (previously coated with Matrigel) for 72 h. The cells were then washed two times in warm PBS and were fixed in 3.7% paraformaldehyde for 20 min at room temperature. Subsequently, the cells were permeabilized with 0.5% Triton X-100 diluted in PBS for 10 min at room temperature, washed three times in PBS, and incubated with rabbit anti-phospho-fascin (FSCN1, Ser39) antibodies diluted 1:100 in PBS (Bioss). After overnight incubation with primary antibodies at 4uC, the cells were washed three times in PBS, incubated with secondary Alexa Fluor 568 goat anti-rabbit antibodies (diluted 1:500 in PBS) for 1 h in the dark at room temperature. Coverslips were then mounted on microscope slides using mounting medium (Sigma Aldrich). Cell imaging was performed using a confocal laser scanning microscope FV-500 system (Olympus Optical Co) with a 488-nm argon laser and 505- to 525-nm filter for FITC staining and with a 543-nm He-Ne laser and a 610-nm filter for Alexa Fluor 568 staining. Images were gathered separately for each fluorescence channel, and the cells were examined using the Fluoview program (Olympus Optical Co.) 100 μL Log in to see 3 to 7 Days
$291.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: HeLa B: Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB Western Blot: Fascin Antibody [NBP1-32708] - Sample (30 ug of whole cell lysate)A: HeLa B: Hep G2 7.5% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 5 to 7 Days
$452.81
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated ICC, FACS, IF, ELISA, WB Flow cytometry: Flow cytometry analysis of FSCN1 in HeLa cell line, staining at 2- 5µg for 1x10^6 cells (red line). The secondary antibody used goat anti-mouse lgG Aexa fluor 488 conjugate. Isotype control antibody was mouse lgG (black line). ICC/IF analysis: ICC/IF analysis of FSCN1 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti- human FSCN1 antibody (1:100) with goat anti-mouse lgG-Aexa fluor 488 conjugate (Green). 50 μL Log in to see 2 to 3 Days
$267.75
Details

FSCN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human


Rat (Rattus)


More Antibodies against Fascin Homolog 1, Actin Bundling Protein (Strongylocentrotus Purpuratus) Interaction Partners

Mouse (Murine) Fascin Homolog 1, Actin Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Fascin1 facilitates phagolysosomal fusion for killing of phagocytosed Listeria. It binds to LC3 (show MAP1LC3A Antibodies), an autophagosome marker, both in vivo & in vitro. It plays a critical role in dendritic cell survivalduring Listeria infection.

  2. A tightly regulated phospho/dephospho-fascin cycle modulated by extracellular signals is required for the polarized morphology and migration in neuroblasts, thus contributing to efficient neurogenesis.

  3. fascin 1 promotes cell migration and has a role in growth and cell cycle progression

  4. Suppression of fascin expression results in reduction of activation-induced migration and invasion in mouse monocytic leukemia (show KAT6B Antibodies) RAW264.7 macrophages.

  5. Both STAT3 (show STAT3 Antibodies) and NFkappaB are required for the cytokine-induced expression of fascin in cancer cells.

  6. fascin-1 is principally expressed in neural and mesenchymal derivatives during embryonic development

  7. We propose that fascin is a key specific actin cross-linker, providing stiffness for filopodial bundles, and that its dynamic behavior allows for efficient coordination between elongation and bundling of filopodial actin filaments.

  8. Fascin is a novel target of beta-catenin (show CTNNB1 Antibodies)-TCF (show HNF4A Antibodies) signaling and is expressed at the invasive front of human colon cancer

  9. Fascin mRNA & protein levels were significantly lower in the cultured ANXA2 (show ANXA2 Antibodies)(-/-) cells than in cultured ANXA2 (show ANXA2 Antibodies)(+/+) cells. ANXA2 (show ANXA2 Antibodies) may be an inducer or enhancer of fascin expression at the transcription level.

  10. study found that Rab35 (show RAB35 Antibodies) regulates the assembly of actin filaments in filopodia formation; effect was mediated by the actin-bundling protein fascin, which directly associated with active Rab35 (show RAB35 Antibodies)

Fascin Homolog 1, Actin Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) Antigen Profile

Protein Summary

Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration (By similarity).

Gene names and symbols associated with FSCN1

  • fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) (Fscn1) antibody
  • AI663989 antibody
  • Fan1 antibody
  • fascin-1 antibody

Protein level used designations for FSCN1

fascin , fascin 1 , singed-like protein

GENE ID SPECIES
14086 Mus musculus
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