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anti-Fatty Acid 2-Hydroxylase (FA2H) Antibodies

FA2H encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Additionally we are shipping Fatty Acid 2-Hydroxylase Proteins (4) and Fatty Acid 2-Hydroxylase Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FA2H 79152 Q7L5A8
FA2H 338521 Q5MPP0
FA2H 307855 Q2LAM0
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Top anti-Fatty Acid 2-Hydroxylase Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of FA2H Antibody (Center) (ABIN650994) in ZR-75-... Western blot analysis of FA2H Antibody (Center) (ABIN650994) in mouse ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$533.50
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB Fa2h antibody used at 2.5 ug/ml to detect target protein. 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details

FA2H Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) , , ,

Top referenced anti-Fatty Acid 2-Hydroxylase Antibodies

  1. Human Polyclonal FA2H Primary Antibody for WB - ABIN265110 : Alderson, Walla, Hama: A novel method for the measurement of in vitro fatty acid 2-hydroxylase activity by gas chromatography-mass spectrometry. in Journal of lipid research 2005 (PubMed)
    Show all 3 references for ABIN265110

  2. Human Polyclonal FA2H Primary Antibody for IHC (p), WB - ABIN650994 : Uchida, Hama, Alderson, Douangpanya, Wang, Crumrine, Elias, Holleran: Fatty acid 2-hydroxylase, encoded by FA2H, accounts for differentiation-associated increase in 2-OH ceramides during keratinocyte differentiation. in The Journal of biological chemistry 2007 (PubMed)

More Antibodies against Fatty Acid 2-Hydroxylase Interaction Partners

Human Fatty Acid 2-Hydroxylase (FA2H) interaction partners

  1. Novel mutations in FA2H in Arab patients with a clinical spectrum of neurodegeneration and hereditary spastic paraparesis were identified.

  2. Three novel mutations in Chinese patients significantly reduce FA2H enzyme activity leading to hereditary spastic paraplegia.

  3. Induced levels of PPARalpha (show PPARA Antibodies) may be involved in the Delta(9)-THC up-regulation of FA2H in MDA-MB-231 cells.

  4. One heterozygous deletion within 16q22.3-q23.1 including FA2H was observed in two siblings who share symptoms of autism and severe cognitive impairment, axial T2-FLAIR weighted MRI (show C7ORF49 Antibodies) posterior periventricular white matter lesions.

  5. Identification of a novel triple heterozygous mutations in FA2H gene (c.968C>A; c.976G>A; c.688G>A) in a Chinese family with Hereditary Spastic Paraplegia Type 35.

  6. FA2H is a novel (9)-THC-regulated gene, and that (9)-THC induces differentiation signal(s) in poorly differentiated MDA-MB-231 cells.

  7. we report a novel mutation in FA2H gene in two sibs presenting with adult onset complicated spastic paraparesis and thin corpus callosum

  8. This study did not find any mutations in the FA2H gene in patients with neurodegeneration with brain iron accumulation.

  9. a novel homozygous c.270+3A>T mutation altered FA2H function led to a severe phenotype, with clinical features overlapping those in three FA2H-associated disorders

  10. The 2-hydroxylated sphingomyelin (SM) profiles were characterized in blood and fibroblasts from patients harboring a deleterious FA2H mutation.

Mouse (Murine) Fatty Acid 2-Hydroxylase (FA2H) interaction partners

  1. the importance of the sebaceous glands and a role of specific sebaceous gland or sebum lipids, synthesized by FA2H, in the hair follicle homeostasis

  2. This study provided the first evidence that FA2H has an important function outside of oligodendrocytes in the Central nervous system.

  3. Our study showed that the additional deletion of Fa2h does not obviously affect the phenotype of Cgt (show UGT8 Antibodies)-/- mice. This suggests that HFA-GlcCer and HFA-sphingomyelin do not functionally compensate the loss of HFA-GalCer in Cgt (show UGT8 Antibodies)-/- mice.

  4. Fndings document the novel role of FA2H in adipocyte lipogenesis possibly by modulation of raft fluidity and level of GLUT4 (show SLC2A4 Antibodies).

  5. FA2H is the enzyme responsible for the formation of alpha-hydroxylated ceramide in oligodendrocytes of the mammalian brain.

  6. FA2H is the major fatty acid 2-hydroxylase in brain, and 2-hydroxylation of free fatty acids is the first step in the synthesis of 2-hydroxy galactolipids

Fatty Acid 2-Hydroxylase (FA2H) Antigen Profile

Protein Summary

This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.

Gene names and symbols associated with FA2H

  • fatty acid 2-hydroxylase (fa2h) antibody
  • fatty acid 2-hydroxylase (FA2H) antibody
  • fatty acid 2-hydroxylase (Tsp_11648) antibody
  • fatty acid hydroxylase (Ilyop_0703) antibody
  • fatty acid hydroxylase (Ftrac_1469) antibody
  • fatty acid hydroxylase (Ftrac_3310) antibody
  • fatty acid hydroxylase (Celal_3558) antibody
  • fatty acid hydroxylase (Celal_4047) antibody
  • fatty acid hydroxylase (Pedsa_2221) antibody
  • fatty acid hydroxylase (Pedsa_3694) antibody
  • fatty acid hydroxylase (Celly_1453) antibody
  • fatty acid hydroxylase (Weevi_1515) antibody
  • fatty acid hydroxylase (Fluta_1455) antibody
  • fatty acid hydroxylase (Halhy_6587) antibody
  • fatty acid hydroxylase (Halhy_1608) antibody
  • fatty acid hydroxylase (Mesop_3301) antibody
  • fatty acid 2-hydroxylase (Fa2h) antibody
  • cb1044 antibody
  • FAAH antibody
  • FAH1 antibody
  • Faxdc1 antibody
  • G630055L08Rik antibody
  • MGC85470 antibody
  • MGC97767 antibody
  • RGD1310347 antibody
  • SCS7 antibody
  • SPG35 antibody
  • Wdr59 antibody
  • zgc:153777 antibody

Protein level used designations for FA2H

fatty acid 2-hydroxylase , fatty acid 2-hydroxylase-like , fatty acid hydroxylase , fatty acid alpha-hydroxylase , fatty acid hydroxylase domain containing 1 , spastic paraplegia 35 (autosomal recessive) , WD repeat domain 59

GENE ID SPECIES
398669 Xenopus laevis
415687 Gallus gallus
454243 Pan troglodytes
516891 Bos taurus
595069 Xenopus (Silurana) tropicalis
610417 Canis lupus familiaris
792257 Danio rerio
10903185 Trichinella spiralis
9868204 Ilyobacter polytropus DSM 2926
10011605 Marivirga tractuosa DSM 4126
10013468 Marivirga tractuosa DSM 4126
10145985 Cellulophaga algicola DSM 14237
10146476 Cellulophaga algicola DSM 14237
10231784 Pedobacter saltans DSM 12145
10233291 Pedobacter saltans DSM 12145
10263467 Cellulophaga lytica DSM 7489
10282765 Weeksella virosa DSM 16922
10396804 Fluviicola taffensis DSM 16823
10584066 Haliscomenobacter hydrossis DSM 1100
10585770 Haliscomenobacter hydrossis DSM 1100
10827138 Mesorhizobium opportunistum WSM2075
79152 Homo sapiens
338521 Mus musculus
307855 Rattus norvegicus
Selected quality suppliers for anti-Fatty Acid 2-Hydroxylase (FA2H) Antibodies
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