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The protein encoded by FADS1 is a member of the fatty acid desaturase (FADS) gene family. Additionally we are shipping Fatty Acid Desaturase 1 Antibodies (75) and Fatty Acid Desaturase 1 Kits (9) and many more products for this protein.
Showing 5 out of 8 products:
polymorphisms in the FADS gene cluster were nominally associated with reduced risk of developing atopic eczema
genetic association study in population of pregnant women in Republic of Seychelles: SNPs in FADS1/FADS2 (show FADS2 Proteins) are associated with maternal arachidonic acid status; a subtle association exists with neurodevelopment in this high fish-eating population. [REVIEW]
Suggest that the FADS1 rs174546 SNP and the FADS2 (show FADS2 Proteins) rs174601 SNP are associated with the risk of coronary artery disease and ischemic stroke, and are likely to influence serum lipid levels.
genome-wide association study in population of mother/infant dyads in Denmark: Data suggest SNPs in maternal FADS1 are associated with (1) lower breast milk polyunsaturated fatty acid and (2) higher production of interleukins by infant T-lymphocytes.
Dietary fatty acids modulate associations between FADS1 genetic variants and circulating fatty acids in plasma and erythrocyte membranes.
Decreased Expression of FADS1 is associated with Esophageal Squamous Cell Carcinoma.
High dietary n-3 LCPUFA intakes could negate the unfavorable effect of genetic variation in FADS1 on CAD in middle-aged and elderly Chinese population.
Data suggest that down-regulation of FADS1 (delta-5 fatty acid desaturase) and up-regulation of FADS2 (delta-6 fatty acid desaturase (show FADS2 Proteins)) in obesity leads to altered long-chain polyunsaturated fatty acid nutritional status. [META-ANALYSIS, REVIEW]
In northern Han Chinese people, the minor allele (T) of rs174616 in the FADS1-FADS2 (show FADS2 Proteins) gene cluster is associated with a decreased conversion rate of Linoleic acid to Arachidonic acid, which may contribute to decreased reduced risk of developing T2 diabetes.
Study shows that docosahexaenoic acid (DHA) and arachidonic acid (ARA (show FOXC1 Proteins)) levels were lower in pregnant women homozygous for FADS1 rs174533 but after DHA supplementation, ARA (show FOXC1 Proteins) level decreases in women homozygous for both FADS1rs174533 and FADS2rs1747575.
knockdown of Elovl5, Fads1, or Fads2 (show FADS2 Proteins) decreased the level of Mead acid.
The Systemic disruption of the Fads1 gene reciprocally altered the levels of dihomo-gamma-linolenic acid and AA in mouse tissues, resulting in a profound increase in 1-series-derived and a concurrent decrease in 2-series-derived prostaglandins.
analysis of mRNA abundance and expression of SLC27A, ACC, SCD, FADS, LPIN, INSIG, and PPARGC1 gene isoforms in mouse mammary glands during the lactation cycle
n-3 fatty acid desaturase (show SCD Proteins) may have a role in colitis-associated colon cancer in mice
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1\; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
, delta(5) fatty acid desaturase
, delta-5 desaturase
, delta-5 fatty acid desaturase
, linoleoyl-CoA desaturase (delta-6-desaturase)-like 1
, fatty acid desaturase 1