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anti-Fatty Acid Desaturase 2 (FADS2) Antibodies

The protein encoded by FADS2 is a member of the fatty acid desaturase (FADS) gene family. Additionally we are shipping FADS2 Kits (13) and FADS2 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FADS2 56473 Q9Z0R9
FADS2 9415 O95864
FADS2 83512 Q9Z122
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Top anti-FADS2 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, WB FADS2 Antibody (Center)(ABIN651561) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the FADS2 antibody detected the FADS2 protein (arrow). FADS2 Antibody (Center)(ABIN651561)western blot analysis in mouse NIH-3T3 cell line lysates (35 µg/lane). This demonstrates the FADS2 antibody detected the FADS2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Fluorescent image of A549 cell stained with FADS2 Antibody (N-term).A549 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with FADS2 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃).FADS2 immunoreactivity is localized to Cytoplasm and Vesicles significantly. FADS2 Antibody (N-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FADS2 antibody detected the FADS2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human liver tissue stained with FADS2 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of FADS2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis in HepG2 cell line lysates (35ug/lane) using FADS2 Antibody (N-term) Cat.-No AP51507PU-N. This demonstrates the FADS2 antibody detected the FADS2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit PE FACS, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Mouse Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$947.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated FACS, ELISA, WB   200 μL Log in to see 11 to 16 Days
$531.14
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

FADS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , ,


, , , , ,
Rat (Rattus)


Top referenced anti-FADS2 Antibodies

  1. Human Polyclonal FADS2 Primary Antibody for FACS, WB - ABIN651561 : Marquardt, Stöhr, White, Weber: cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family. in Genomics 2000 (PubMed)
    Show all 2 references for ABIN651561

  2. Human Polyclonal FADS2 Primary Antibody for EIA, IHC (p) - ABIN952158 : Mathias, Vergara, Gao, Rafaels, Hand, Campbell, Bickel, Ivester, Sergeant, Barnes, Chilton: FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population. in Journal of lipid research 2010 (PubMed)
    Show all 2 references for ABIN952158

  3. Human Polyclonal FADS2 Primary Antibody for FACS, IF - ABIN656230 : Steer, Davey Smith, Emmett, Hibbeln, Golding: FADS2 polymorphisms modify the effect of breastfeeding on child IQ. in PLoS ONE 2010 (PubMed)

More Antibodies against FADS2 Interaction Partners

Zebrafish Fatty Acid Desaturase 2 (FADS2) interaction partners

  1. these results implicate that Z-FADS, the sole fatty acid desaturase (show SCD Antibodies) ever been identified in zebrafish, can serve as a universal fatty acid desaturase (show SCD Antibodies) during lipogenesis.

Mouse (Murine) Fatty Acid Desaturase 2 (FADS2) interaction partners

  1. FADS2 deficient mice are obesity resistant.

  2. knockdown of Elovl5 (show ELOVL5 Antibodies), Fads1 (show FADS1 Antibodies), or Fads2 decreased the level of Mead acid.

  3. D6D activity is upregulated during melanoma and lung tumor growth and that suppressing D6D activity, either by RNAi knockdown or a specific D6D inhibitor, dramatically reduces tumor growth.

  4. Results suggest that Fads2 is essential for spermatogenesis; Fads2-/- knockout mice develop docosahexaenoic acid deficiency and acrosome biogenesis is halted after release of proacrosomal granules.

  5. analysis of macrophage cholesterol biosynthesis and decreased cellular paraoxonase 2 (PON2 (show PON2 Antibodies)) expression in Delta6-desaturase knockout (6-DS KO) mice

  6. We created D6D-null mice (-/-), which enabled us to study highly unsaturated fatty acid deficiency without depleting their precursors.

  7. methylation silencing of liver Fads2 expression and changes in liver fatty acids may contribute to the pathology of hyperhomocysteinemia.

  8. deletion of delta6-fatty acid desaturase (show SCD Antibodies) (FADS2) gene expression abolishes the initial step in the enzymatic cascade of PUFA synthesis

Human Fatty Acid Desaturase 2 (FADS2) interaction partners

  1. We investigated the association of surgery-induced weight loss and FA desaturase (FADS)1/2 genotypes with serum and AT FA profile and with AT inflammation, measured as interleukin (IL)-1beta and NFkappaB pathway gene expression.

  2. genetic association study in population of pregnant women in Republic of Seychelles: SNPs in FADS1 (show FADS1 Antibodies)/FADS2 are associated with maternal arachidonic acid status; a subtle association exists with neurodevelopment in this high fish-eating population. [REVIEW]

  3. FADS2 has been shown to be important in the metabolism of polyunsaturated fatty acids.

  4. FADS2 has been shown to be important in the metabolism of polyunsaturated fatty acids.

  5. Suggest that the FADS1 (show FADS1 Antibodies) rs174546 SNP and the FADS2 rs174601 SNP are associated with the risk of coronary artery disease and ischemic stroke, and are likely to influence serum lipid levels.

  6. Data suggest that up-regulation of FADS2 (delta-6 fatty acid desaturase) and down-regulation of FADS1 (delta-5 fatty acid desaturase (show FADS1 Antibodies)) in obesity leads to altered long-chain polyunsaturated fatty acid nutritional status. [META-ANALYSIS, REVIEW]

  7. In northern Han Chinese people, the minor allele (T) of rs174616 in the FADS1 (show FADS1 Antibodies)-FADS2 gene cluster is associated with a decreased conversion rate of Linoleic acid to Arachidonic acid, which may contribute to decreased reduced risk of developing T2 diabetes.

  8. Loss of FADS2 function severely impairs the use of HeLa cells as an in vitro model for host response studies involving fatty acid effects.

  9. The enzyme C440A is also able to catalyse hydrolysis of FAD (show BRCA2 Antibodies) bound to the PAPS (show PAPSS1 Antibodies) reductase domain, which is quantitatively converted into FMN (show FMN1 Antibodies).

  10. results demonstrate that the FADS2 classical transcript mediates direct Delta4 desaturation to yield 22:6n-3 and 22:5n-6 in human cells

FADS2 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1\; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

Gene names and symbols associated with FADS2

  • fatty acid desaturase 2 (fads2) antibody
  • fatty acid desaturase 2 (Fads2) antibody
  • fatty acid desaturase 2 (FADS2) antibody
  • 2900042M13Rik antibody
  • D6D antibody
  • DES6 antibody
  • DRD5/D6 antibody
  • Fadsd2 antibody
  • FADSD6 antibody
  • LLCDL2 antibody
  • SLL0262 antibody
  • TU13 antibody
  • wu:fb64c04 antibody
  • wu:fb69e08 antibody
  • zgc:112502 antibody

Protein level used designations for FADS2

D5D/D6D fatty acid desaturase , delta(5)/Delta(6) fatty acid desaturase , delta-5/Delta-6 fatty acid desaturase , delta-6 fatty acyl desaturase , D6D , delta(6) desaturase , delta(6) fatty acid desaturase , delta-6 desaturase , delta-6 fatty acid desaturase , delta-6-desaturase , linoleoyl-CoA desaturase (delta-6-desaturase)-like 2 , fatty acid desaturase 6

GENE ID SPECIES
140615 Danio rerio
56473 Mus musculus
9415 Homo sapiens
83512 Rattus norvegicus
521822 Bos taurus
423122 Gallus gallus
444997 Sus scrofa
100190814 Pongo abelii
446688 Xenopus laevis
Selected quality suppliers for anti-FADS2 (FADS2) Antibodies
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