You are viewing an incomplete version of our website. Please click to reload the website as full version.

Fatty Acid Desaturase 2 Proteins (FADS2)

The protein encoded by FADS2 is a member of the fatty acid desaturase (FADS) gene family. Additionally we are shipping FADS2 Antibodies (46) and FADS2 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FADS2 56473 Q9Z0R9
FADS2 9415 O95864
Rat FADS2 FADS2 83512 Q9Z122
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top FADS2 Proteins at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FADS2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
, ,

More Proteins for Fatty Acid Desaturase 2 (FADS2) Interaction Partners

Zebrafish Fatty Acid Desaturase 2 (FADS2) interaction partners

  1. these results implicate that Z-FADS, the sole fatty acid desaturase (show SCD Proteins) ever been identified in zebrafish, can serve as a universal fatty acid desaturase (show SCD Proteins) during lipogenesis.

Mouse (Murine) Fatty Acid Desaturase 2 (FADS2) interaction partners

  1. FADS2 deficient mice are obesity resistant.

  2. knockdown of Elovl5, Fads1 (show FADS1 Proteins), or Fads2 decreased the level of Mead acid.

  3. D6D activity is upregulated during melanoma and lung tumor growth and that suppressing D6D activity, either by RNAi knockdown or a specific D6D inhibitor, dramatically reduces tumor growth.

  4. Results suggest that Fads2 is essential for spermatogenesis; Fads2-/- knockout mice develop docosahexaenoic acid deficiency and acrosome biogenesis is halted after release of proacrosomal granules.

  5. analysis of macrophage cholesterol biosynthesis and decreased cellular paraoxonase 2 (PON2 (show PON2 Proteins)) expression in Delta6-desaturase knockout (6-DS KO) mice

  6. We created D6D-null mice (-/-), which enabled us to study highly unsaturated fatty acid deficiency without depleting their precursors.

  7. methylation silencing of liver Fads2 expression and changes in liver fatty acids may contribute to the pathology of hyperhomocysteinemia.

  8. deletion of delta6-fatty acid desaturase (show SCD Proteins) (FADS2) gene expression abolishes the initial step in the enzymatic cascade of PUFA synthesis

Human Fatty Acid Desaturase 2 (FADS2) interaction partners

  1. We investigated the association of surgery-induced weight loss and FA desaturase (FADS)1/2 genotypes with serum and AT FA profile and with AT inflammation, measured as interleukin (IL)-1beta and NFkappaB pathway gene expression.

  2. genetic association study in population of pregnant women in Republic of Seychelles: SNPs in FADS1 (show FADS1 Proteins)/FADS2 are associated with maternal arachidonic acid status; a subtle association exists with neurodevelopment in this high fish-eating population. [REVIEW]

  3. FADS2 has been shown to be important in the metabolism of polyunsaturated fatty acids.

  4. FADS2 has been shown to be important in the metabolism of polyunsaturated fatty acids.

  5. Suggest that the FADS1 (show FADS1 Proteins) rs174546 SNP and the FADS2 rs174601 SNP are associated with the risk of coronary artery disease and ischemic stroke, and are likely to influence serum lipid levels.

  6. Data suggest that up-regulation of FADS2 (delta-6 fatty acid desaturase) and down-regulation of FADS1 (delta-5 fatty acid desaturase (show FADS1 Proteins)) in obesity leads to altered long-chain polyunsaturated fatty acid nutritional status. [META-ANALYSIS, REVIEW]

  7. In northern Han Chinese people, the minor allele (T) of rs174616 in the FADS1 (show FADS1 Proteins)-FADS2 gene cluster is associated with a decreased conversion rate of Linoleic acid to Arachidonic acid, which may contribute to decreased reduced risk of developing T2 diabetes.

  8. Loss of FADS2 function severely impairs the use of HeLa cells as an in vitro model for host response studies involving fatty acid effects.

  9. The enzyme C440A is also able to catalyse hydrolysis of FAD (show BRCA2 Proteins) bound to the PAPS (show PAPSS1 Proteins) reductase domain, which is quantitatively converted into FMN (show FMN1 Proteins).

  10. results demonstrate that the FADS2 classical transcript mediates direct Delta4 desaturation to yield 22:6n-3 and 22:5n-6 in human cells

FADS2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1\; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

Gene names and symbols associated with FADS2

  • fatty acid desaturase 2 (fads2)
  • fatty acid desaturase 2 (Fads2)
  • fatty acid desaturase 2 (FADS2)
  • 2900042M13Rik protein
  • D6D protein
  • DES6 protein
  • DRD5/D6 protein
  • Fadsd2 protein
  • FADSD6 protein
  • LLCDL2 protein
  • SLL0262 protein
  • TU13 protein
  • wu:fb64c04 protein
  • wu:fb69e08 protein
  • zgc:112502 protein

Protein level used designations for FADS2

D5D/D6D fatty acid desaturase , delta(5)/Delta(6) fatty acid desaturase , delta-5/Delta-6 fatty acid desaturase , delta-6 fatty acyl desaturase , D6D , delta(6) desaturase , delta(6) fatty acid desaturase , delta-6 desaturase , delta-6 fatty acid desaturase , delta-6-desaturase , linoleoyl-CoA desaturase (delta-6-desaturase)-like 2 , fatty acid desaturase 6

GENE ID SPECIES
140615 Danio rerio
56473 Mus musculus
9415 Homo sapiens
83512 Rattus norvegicus
521822 Bos taurus
423122 Gallus gallus
444997 Sus scrofa
100190814 Pongo abelii
446688 Xenopus laevis
Selected quality suppliers for FADS2 Proteins (FADS2)
Did you look for something else?