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anti-Fc Fragment of IgA, Receptor For (FCAR) Antibodies

FCAR is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. Additionally we are shipping Fc Fragment of IgA, Receptor For Kits (12) and Fc Fragment of IgA, Receptor For Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FCAR 2204 P24071
FCAR    
FCAR    
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Top anti-Fc Fragment of IgA, Receptor For Antibodies at antibodies-online.com

Showing 10 out of 146 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of FCAR (arrow) using rabbit polyclonal FCAR Ant... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse PE FACS ABIN118856 (Mouse anti human CD89: RPE) staining of peripheral blood g... 100 Tests Log in to see 6 to 8 Days
$434.50
Details
Human Mouse Un-conjugated EIA, FACS, IP, WB   25 μg Log in to see 6 to 8 Days
$176.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of FCAR (arrow) using rabbit polyclonal FCAR Ant... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IF   1 mg Log in to see 6 to 8 Days
$445.50
Details
Human Mouse FITC FACS Flow cytometric analysis of anti-human CD89 on human whole blood granu... 50 Tests Log in to see 16 Days
$198.00
Details
Human Mouse PE ICFC 100 Tests Log in to see 10 to 12 Days
$266.33
Details
Human Mouse APC ICFC 100 Tests Log in to see 10 to 12 Days
$266.33
Details
Human Mouse PE-Cy7 FACS 100 Tests Log in to see 10 to 12 Days
$342.43
Details
Human Mouse PerCP-Cy5.5 FACS 100 Tests Log in to see 10 to 12 Days
$353.29
Details

FCAR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Rat (Rattus) , ,

Mouse (Murine) , ,

Top referenced anti-Fc Fragment of IgA, Receptor For Antibodies

  1. Human Monoclonal FCAR Primary Antibody for ICFC - ABIN2662687 : Honorio-França, Launay, Carneiro-Sampaio, Monteiro: Colostral neutrophils express Fc alpha receptors (CD89) lacking gamma chain association and mediate noninflammatory properties of secretory IgA. in Journal of leukocyte biology 2001 (PubMed)
    Show all 6 references for ABIN2662687

  2. Human Monoclonal FCAR Primary Antibody for FACS - ABIN2659333 : Patry, Sibille, Lehuen, Monteiro: Identification of Fc alpha receptor (CD89) isoforms generated by alternative splicing that are differentially expressed between blood monocytes and alveolar macrophages. in Journal of immunology (Baltimore, Md. : 1950) 1996 (PubMed)
    Show all 6 references for ABIN2659333

  3. Human Monoclonal FCAR Primary Antibody for FACS - ABIN2660166 : de Wit, Morton, Capel, van de Winkel: Structure of the gene for the human myeloid IgA Fc receptor (CD89). in Journal of immunology (Baltimore, Md. : 1950) 1995 (PubMed)
    Show all 6 references for ABIN2660166

  4. Human Monoclonal FCAR Primary Antibody for ICFC - ABIN2658286 : Monteiro, Cooper, Kubagawa: Molecular heterogeneity of Fc alpha receptors detected by receptor-specific monoclonal antibodies. in Journal of immunology (Baltimore, Md. : 1950) 1992 (PubMed)
    Show all 6 references for ABIN2658286

  5. Human Monoclonal FCAR Primary Antibody for FACS, IF - ABIN1106598 : Zhang, Bi, Oldroyd, Lachmann: Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8a. in Clinical and experimental immunology 2000 (PubMed)
    Show all 2 references for ABIN1106598

  6. Human Monoclonal FCAR Primary Antibody for FACS - ABIN118856 : Lu, Marjon, Marnell, Wang, Mold, Du Clos, Sun: Recognition and functional activation of the human IgA receptor (FcalphaRI) by C-reactive protein. in Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)
    Show all 2 references for ABIN118856

  7. Human Polyclonal FCAR Primary Antibody for EIA, WB - ABIN951425 : Peng, Yin, Zhang: Endocytosis of FcalphaR is clathrin and dynamin dependent, but its cytoplasmic domain is not required. in Cell research 2010 (PubMed)
    Show all 2 references for ABIN951425

More Antibodies against Fc Fragment of IgA, Receptor For Interaction Partners

Cow (Bovine) Fc Fragment of IgA, Receptor For (FCAR) interaction partners

  1. have mapped the IgA binding site of bovine IgA Fc receptor and show that, in common with CD89, Tyr-35 in the B-C loop is essential for IgA binding

Human Fc Fragment of IgA, Receptor For (FCAR) interaction partners

  1. Findings suggest a basis for the use of Fc receptor I for IgA (FcalphaRI) as a molecular target for the treatment of lupus.

  2. this study examined the expression of IL-4 mRNA, IFN-c mRNA and FcaRI mRNA in tonsillar mononuclear cells of IgA nephropathy9(IgAN) patients and non-IgAN patients.

  3. FCAR polymorphism is not associated with high susceptibility to IGA nephropathy in caucasians.

  4. Abnormally glycosylated IgA1 and soluble CD89-IgA and IgA-IgG complexes, features of primary IgA nephropathy, are also present in alcoholic cirrhosis.

  5. Genetic variation at the promoter region of IgA receptor is associated with IgA nephropathy.

  6. These results suggest a role of anti-FcaRI Fab (show FANCB Antibodies) as a negative regulator in controlling the magnitude of the innate immune response

  7. Glycosylation of the CH2 (show Acyp1 Antibodies)/CH3 (show SOX3 Antibodies) interface inhibits interaction with the pathogen IgA binding protein SSL7, while maintaining binding of pIgR (show PIGR Antibodies), essential to the biosynthesis and transport of SIgA.

  8. There is an association between the levels of sCD89-IgA complexes in serum and the severity of IgA nephropathy, and a possible genetic component in regulating the production or expression of sCD89.

  9. Endocytosis of FcalphaR is clathrin- and dynamin (show DNM1 Antibodies)-dependent, but is not regulated by Rab5 (show RAB5A Antibodies), and the endocytic motif is not located in the cytoplasmic domain of FcalphaR.

  10. CD89 circulates in a high molecular mass form in complex covalently linked to IgA and contributes to the formation of polymeric serum IgA.

Fc Fragment of IgA, Receptor For (FCAR) Antigen Profile

Protein Summary

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with FCAR

  • Fc fragment of IgA, receptor for (FCAR) antibody
  • CD89 antibody

Protein level used designations for FCAR

IgA Fc receptor , immunoglobulin A Fc receptor , immunoglobulin alpha Fc receptor , Fc fragment of IgA, receptor for, isoform 7 , Fc alpha receptor

GENE ID SPECIES
503555 Bos taurus
664734 Macaca mulatta
100050205 Equus caballus
100137567 Papio anubis
100144539 Sus scrofa
2204 Homo sapiens
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