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FCAR is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. Additionally we are shipping Fc Fragment of IgA, Receptor For Proteins (12) and Fc Fragment of IgA, Receptor For Kits (6) and many more products for this protein.
Showing 10 out of 185 products:
Human Monoclonal FCAR Primary Antibody for ICFC - ABIN2662687
Honorio-França, Launay, Carneiro-Sampaio, Monteiro: Colostral neutrophils express Fc alpha receptors (CD89) lacking gamma chain association and mediate noninflammatory properties of secretory IgA. in Journal of leukocyte biology 2001
Show all 6 references for ABIN2662687
Human Monoclonal FCAR Primary Antibody for FACS - ABIN2659333
Patry, Sibille, Lehuen, Monteiro: Identification of Fc alpha receptor (CD89) isoforms generated by alternative splicing that are differentially expressed between blood monocytes and alveolar macrophages. in Journal of immunology (Baltimore, Md. : 1950) 1996
Show all 6 references for ABIN2659333
Human Monoclonal FCAR Primary Antibody for FACS - ABIN2660166
de Wit, Morton, Capel, van de Winkel: Structure of the gene for the human myeloid IgA Fc receptor (CD89). in Journal of immunology (Baltimore, Md. : 1950) 1995
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Human Monoclonal FCAR Primary Antibody for FACS, ICFC - ABIN2664856
Monteiro, Cooper, Kubagawa: Molecular heterogeneity of Fc alpha receptors detected by receptor-specific monoclonal antibodies. in Journal of immunology (Baltimore, Md. : 1950) 1992
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Human Monoclonal FCAR Primary Antibody for ICFC - ABIN2658286
Rogers, Scinicariello, Attanasio: Identification and characterization of macaque CD89 (immunoglobulin A Fc receptor). in Immunology 2004
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Human Monoclonal FCAR Primary Antibody for FACS, IF - ABIN1106598
Zhang, Bi, Oldroyd, Lachmann: Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8a. in Clinical and experimental immunology 2000
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Human Monoclonal FCAR Primary Antibody for FACS - ABIN118856
Lu, Marjon, Marnell, Wang, Mold, Du Clos, Sun: Recognition and functional activation of the human IgA receptor (FcalphaRI) by C-reactive protein. in Proceedings of the National Academy of Sciences of the United States of America 2011
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Human Polyclonal FCAR Primary Antibody for EIA, WB - ABIN951425
Peng, Yin, Zhang: Endocytosis of FcalphaR is clathrin and dynamin dependent, but its cytoplasmic domain is not required. in Cell research 2010
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have mapped the IgA binding site of bovine IgA Fc receptor and show that, in common with CD89, Tyr-35 in the B-C loop is essential for IgA binding
Findings suggest a basis for the use of Fc receptor I for IgA (FcalphaRI) as a molecular target for the treatment of lupus.
this study examined the expression of IL-4 mRNA, IFN-c mRNA and FcaRI mRNA in tonsillar mononuclear cells of IgA nephropathy9(IgAN) patients and non-IgAN patients.
FCAR polymorphism is not associated with high susceptibility to IGA nephropathy in caucasians.
Abnormally glycosylated IgA1 and soluble CD89-IgA and IgA-IgG complexes, features of primary IgA nephropathy, are also present in alcoholic cirrhosis.
Genetic variation at the promoter region of IgA receptor is associated with IgA nephropathy.
These results suggest a role of anti-FcaRI Fab (show FANCB Antibodies) as a negative regulator in controlling the magnitude of the innate immune response
Glycosylation of the CH2 (show Acyp1 Antibodies)/CH3 (show SOX3 Antibodies) interface inhibits interaction with the pathogen IgA binding protein SSL7, while maintaining binding of pIgR (show PIGR Antibodies), essential to the biosynthesis and transport of SIgA.
There is an association between the levels of sCD89-IgA complexes in serum and the severity of IgA nephropathy, and a possible genetic component in regulating the production or expression of sCD89.
Endocytosis of FcalphaR is clathrin- and dynamin (show DNM1 Antibodies)-dependent, but is not regulated by Rab5 (show RAB5A Antibodies), and the endocytic motif is not located in the cytoplasmic domain of FcalphaR.
CD89 circulates in a high molecular mass form in complex covalently linked to IgA and contributes to the formation of polymeric serum IgA.
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
IgA Fc receptor
, immunoglobulin A Fc receptor
, immunoglobulin alpha Fc receptor
, Fc fragment of IgA, receptor for, isoform 7
, Fc alpha receptor