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Fc Receptor-Like 5 Proteins (FCRL5)

FCRL5 encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. Additionally we are shipping Fc Receptor-Like 5 Antibodies (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FCRL5 83416 Q96RD9
FCRL5 329693 Q68SN8
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Top Fc Receptor-Like 5 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details

FCRL5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) ,
,

More Proteins for Fc Receptor-Like 5 (FCRL5) Interaction Partners

Human Fc Receptor-Like 5 (FCRL5) interaction partners

  1. Data suggest that expression of FCRL5 (but not FCRL4 (show FCRL4 Proteins)) on surface of atypical (perhaps dysfunctional) memory B-Lymphocytes is up-regulated by exposure to Plasmodium falciparum antigens in subjects in Uganda where malaria is endemic.

  2. FCRL5 is a new type of receptor that recognizes intact IgG, possibly enabling B cells to sense Ig quality. Recognition of undamaged IgG molecules by FCRL5 could allow B cells to engage recently produced Abs.

  3. FcRL5 binds all immunoglobulin (Ig)G isotypes with varied efficiency.

  4. Enhanced proliferation and downstream isotype expression upon FCRL5 stimulation could reflect a physiological role for FCRL5 in the expansion and development of antigen-primed B cells.

  5. Three of the FCRL5 tag SNPs, rs6667109, rs3811035 and rs6692977 showed association with Graves' disease. association with FCRL5 was secondary to linkage disequilibrium with the FCRL3 (show FCRL3 Proteins), rs11264798 and rs10489678 SNPs.

  6. IRTA2 is expressed on the surface of human lymphoma cell lines and hairy cell leukemia cells

  7. results identify FcRH5 as a novel, direct target of EBNA2 that may contribute to the development of Epstein-Barr virus-associated tumors

  8. IRTA2/FcRH5 may have a role in hairy cell leukemia

  9. Fc receptor-like 1 (show FCRL1 Proteins)-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.

  10. Down-regulation of FCRL5 is associated with acute lymphoblastic leukemia.

Mouse (Murine) Fc Receptor-Like 5 (FCRL5) interaction partners

  1. FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling.

  2. The three amino-terminal immunoglobulin domains of FCRL5 are required for binding of orthopoxvirus histocompatibility class I-like protein to B (show TDO2 Proteins) cells and monocytes/macrophages.

  3. Fc receptor-like 5 inhibits B cell activation via SHP-1 tyrosine phosphatase recruitment.

Fc Receptor-Like 5 (FCRL5) Protein Profile

Protein Summary

This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with Fc Receptor-Like 5 Proteins (FCRL5)

  • Fc receptor-like 5 (FCRL5)
  • Fc receptor-like 5 (Fcrl5)
  • BXMAS1 protein
  • CD307 protein
  • CD307e protein
  • Fcrh3 protein
  • FCRH5 protein
  • FCRL5 protein
  • IRTA2 protein
  • mBXMH2 protein
  • PRO820 protein

Protein level used designations for Fc Receptor-Like 5 Proteins (FCRL5)

Fc receptor-like 5 , fc receptor-like protein 5-like , Fc receptor-like protein 5-like , Fc receptor-like protein 5 , fc receptor homolog 5 , fcR-like protein 5 , immune receptor translocation-associated protein 2 , immunoglobulin superfamily receptor translocation associated 2 (IRTA2) , BXMAS1-like protein 2 , Fc receptor-like protein 3 , fc receptor homolog 3 , moFcRH3

GENE ID SPECIES
469518 Pan troglodytes
100415439 Callithrix jacchus
100444053 Pongo abelii
100594553 Nomascus leucogenys
83416 Homo sapiens
329693 Mus musculus
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