Fc Receptor-Like 2 Proteins (FCRL2)

FCRL2 encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. Additionally we are shipping FCRL2 Antibodies (15) and FCRL2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FCRL2 79368 Q96LA5
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Top FCRL2 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Human Cells Human His tag SDS-PAGE 50 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details

FCRL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Fc Receptor-Like 2 (FCRL2) Interaction Partners

Human Fc Receptor-Like 2 (FCRL2) interaction partners

  1. decreased FCRL4 (show FCRL4 Proteins) expression and association of FCRL2 expression with inflammatory markers and disease activity suggested the contribution of these molecules to rheumatoid arthritis inflammatory processes.

  2. FCRL2 overexpression in B cells from Hashimoto and Graves disease patients compared to normal subjects.

  3. a negative immunomodulatory function for FCRL2 in the regulation of memory B cells.

  4. B-CLL patients with high FCRL2 expression had a significantly longer treatment-free survival & overall survival than those with low FCRL2.

  5. FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in chronic lymphocytic leukemia.

  6. Fc receptor-like 1 (show FCRL1 Proteins)-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.

  7. Down-regulation of FCRL2 is associated with acute lymphoblastic leukemia.

FCRL2 Protein Profile

Protein Summary

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with Fc Receptor-Like 2 Proteins (FCRL2)

  • Fc receptor-like 2 (FCRL2)
  • Fc receptor-like 2 (fcrl2)
  • CD307b protein
  • fcrh2 protein
  • ifgp4 protein
  • irta4 protein
  • spap1 protein
  • spap1a protein
  • spap1b protein
  • spap1c protein

Protein level used designations for Fc Receptor-Like 2 Proteins (FCRL2)

Fc receptor-like protein 2 , IFGP family protein 4 , SH2 domain containing phosphatase anchor protein 1 , SH2 domain-containing phosphatase anchor protein 1 , fc receptor homolog 2 , fcR-like protein 2 , immune receptor translocation-associated protein 4 , immunoglobulin receptor translocation-associated protein 4 , immunoglobulin superfamily Fc receptor, gp42 , Fc receptor-like 2 , type I TM-receptor XFL1.1b , Fc receptor-like protein 2-like

GENE ID SPECIES
79368 Homo sapiens
426461 Gallus gallus
469520 Pan troglodytes
612038 Canis lupus familiaris
718824 Macaca mulatta
779035 Xenopus laevis
100446148 Pongo abelii
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