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anti-Fem-1 Homolog B (C. Elegans) (FEM1B) Antibodies

Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Additionally we are shipping Fem-1 Homolog B (C. Elegans) Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FEM1B 10116 Q9UK73
FEM1B 315745 P0C6P7
FEM1B 14155 Q9Z2G0
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Top anti-Fem-1 Homolog B (C. Elegans) Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-FEM1B Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FEM1B Antibody Titration: 0.2-1 ug/mlPositive Control: Human Lung Host: Rabbit  Target Name: FEM1B  Sample Tissue: Human Fetal Heart  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of F1Aα in mouse liver tissue with F1Aalpha antibody at 5 μg/ml. Western blot analysis of F1A alpha in mouse (A) and rat (B) liver tissue lysates with AP30325PU-N F1A alpha antibody at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with FEM1B antibody ABIN214493 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat testis labeled with Rabbit Anti-FEM 1B Polyclonal Antibody, Unconjugated (ABIN873113) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

FEM1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Fem-1 Homolog B (C. Elegans) Antibodies

  1. Human Polyclonal FEM1B Primary Antibody for EIA, IHC (p) - ABIN499814 : Chan, Tan, Zhang, Yee, Ronca, Chan, Yu: F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis. in The Journal of biological chemistry 1999 (PubMed)
    Show all 3 references for ABIN499814

  2. Cow (Bovine) Polyclonal FEM1B Primary Antibody for WB - ABIN2774057 : Kamura, Maenaka, Kotoshiba, Matsumoto, Kohda, Conaway, Conaway, Nakayama: VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases. in Genes & development 2004 (PubMed)

More Antibodies against Fem-1 Homolog B (C. Elegans) Interaction Partners

Human Fem-1 Homolog B (C. Elegans) (FEM1B) interaction partners

  1. These findings have implications for understanding the cellular functions of Fem1b, and the regulation of Gli1 (show GLI1 Antibodies) oncoprotein activity.

  2. the proapoptotic protein Fem1b is downregulated by the proteasome in malignant colon cancer cells and mediates proteasome inhibitor-induced apoptosis of these cells

  3. This study presents evidence suggesting a role for FEM1A (show FEM1A Antibodies) and FEM1B in the pathogenesis of polycystic ovary syndrome. Only FEM1B variants were associated with insulin (show INS Antibodies)-related traits in PCOS women.

  4. FEM1B is required for Rad9 (show RAD9A Antibodies) recruitment and CHK1 (show CHEK1 Antibodies) activation in response to replication stress.

Mouse (Murine) Fem-1 Homolog B (C. Elegans) (FEM1B) interaction partners

  1. Fem1b is a binding partner of Ankrd37, and their interaction resulted in Ankrd37 degradation through the ubiquitin-mediated proteolysis pathway.

  2. Increased Fem1b is associated with intestinal neoplasia.

  3. neither FEM1B nor PHTF1 (show PHTF1 Antibodies) are directly implicated in apoptosis in testis tissue

  4. Fem1b is implicated in pancreatic islet function and insulin (show INS Antibodies) secretion

  5. Fem1b may have a conserved role in the generation of sexual dimorphism through its interaction with Nkx3.1 (show NKX3-1 Antibodies) in the developing prostate gland

Fem-1 Homolog B (C. Elegans) (FEM1B) Antigen Profile

Protein Summary

Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet (By similarity). Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity).

Gene names and symbols associated with FEM1B

  • protein fem-1 homolog B (Fem-1) antibody
  • fem-1 homolog b (C. elegans) (FEM1B) antibody
  • fem-1 homolog b (C. elegans) (fem1b) antibody
  • similar to fem-1 homolog a (C.elegans) (FEM1B) antibody
  • fem-1 homolog b (fem1b) antibody
  • fem-1 homolog b (C. elegans) (Fem1b) antibody
  • feminization 1 homolog b (C. elegans) (Fem1b) antibody
  • F1A-ALPHA antibody
  • F1AA antibody
  • FEM1-beta antibody
  • FEM1B antibody
  • mKIAA0396 antibody

Protein level used designations for FEM1B

protein fem-1 homolog B , fem-1 homolog b (C. elegans) , similar to fem-1 homolog a (C.elegans) , FEM1-beta , feminization-1 , FEM-1-like death receptor binding protein , fem-1-like death receptor-binding protein alpha , fem-1-like in apoptotic pathway protein alpha , feminization 1 homolog b , F1A-alpha , mt-Fem

GENE ID SPECIES
413692 Apis mellifera
467716 Pan troglodytes
567119 Danio rerio
693955 Macaca mulatta
694843 Macaca mulatta
100052688 Equus caballus
100344502 Oryctolagus cuniculus
100589391 Nomascus leucogenys
444111 Xenopus laevis
10116 Homo sapiens
315745 Rattus norvegicus
415559 Gallus gallus
478352 Canis lupus familiaris
540252 Bos taurus
14155 Mus musculus
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