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Ferritin, Heavy Polypeptide 1 Proteins (FTH1)

FTH1 encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. Additionally we are shipping Ferritin, Heavy Polypeptide 1 Antibodies (166) and Ferritin, Heavy Polypeptide 1 Kits (49) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FTH1 14319 P09528
FTH1 2495 P02794
FTH1 25319 P19132
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Top Ferritin, Heavy Polypeptide 1 Proteins at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Please inquire GST tag Ferritin, Heavy Polypeptide 1 (FTH1) (AA 2-183), (full length) protein (GST tag) 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag Ferritin, Heavy Polypeptide 1 (FTH1) (AA 2-183), (full length) protein (His tag) 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 7 to 9 Days
$480.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,374.17
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$2,396.17
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details

FTH1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,
Rat (Rattus) ,

Top referenced Ferritin, Heavy Polypeptide 1 Proteins

  1. FTH1 Protein expressed in Escherichia coli (E. coli) - ABIN1047000 : Costanzo, Santoro, Colantuoni, Bensi, Raugei, Romano, Cortese: Cloning and sequencing of a full length cDNA coding for a human apoferritin H chain: evidence for a multigene family. in The EMBO journal 1984 (PubMed)
    Show all 3 references for ABIN1047000

  2. Human FTH1 Protein expressed in Escherichia coli (E. coli) - ABIN667083 : Levens, Luo, Ding, Williams, Chegini: Fibromodulin is expressed in leiomyoma and myometrium and regulated by gonadotropin-releasing hormone analogue therapy and TGF-beta through Smad and MAPK-mediated signalling. in Molecular human reproduction 2005 (PubMed)
    Show all 2 references for ABIN667083

More Proteins for Ferritin, Heavy Polypeptide 1 (FTH1) Interaction Partners

Arabidopsis thaliana Ferritin, Heavy Polypeptide 1 (FTH1) interaction partners

  1. Fe mediated decrease of lateral root length and density is enhanced in fer1-3-4 triple mutant plants.

  2. phosphate starvation response of AtFer1 is not linked to the iron status of plants and is specifically initiated by phosphate deficiency

  3. Data indicate that steady-state mRNA abundance for three representative Fe homeostasis genes, IRT1 (show PARP3 Proteins), bHLH39, and FER1, oscillated in light/dark (LD) cycles or warm/cold environmental cycles.

  4. Data show that a leaf glutathione concentration threshold between 10 and 50 nmol GSHg(-1) FW is required for full induction of AtFer1 gene expression in response to iron.

  5. new regulatory pathway involved in plant response to oxidative stress was revealed using the iron-induced Arabidopsis ferritin (show FTL Proteins) AtFER1 as a model

  6. Ferritin (show FTL Proteins) accumulation during infection of Arabidopsis by E. chrysanthemi is a basal defense mechanism which is mainly activated by bacterial siderophores.

Horse (Equine) Ferritin, Heavy Polypeptide 1 (FTH1) interaction partners

  1. The X-ray crystal structure of the apoferritin-SDS (show SDS Proteins) complex was determined at a resolution of 1.9 A and revealed that the SDS (show SDS Proteins) binds in an internal cavity that has previously been shown to recognize various general anesthetics. [apoferritin]

  2. Transmission electron microscopy shows a clear selectivity of alkylated ferritin (show FTL Proteins) adsorption onto the PCL (show PKD2L1 Proteins) phase while wild ferritin (show FTL Proteins) predominantly adsorbs onto the PDTD phase.

Mouse (Murine) Ferritin, Heavy Polypeptide 1 (FTH1) interaction partners

  1. As previously reported, homozygous loss of the Fth allele on a wild-type Ftl (show FTL Proteins) background was embryonic lethal. expression of the H subunit can rescue the loss of the L subunit and that H ferritin homopolymers have the capacity to sequester iron in vivo

  2. provide a new mechanism for selective autophagy of ferritin (show FTL Proteins) and reveal a previously unappreciated role for autophagy and NCOA4 (show NCOA4 Proteins) in the control of iron homeostasis in vivo

  3. Our data show that ferritin H (show FTMT Proteins) is required for B and T cell survival by actively reducing the labile iron pool.

  4. Ferritin H (show FTMT Proteins) deficiency in most cells of the forebrain including cells of the choroid plexus caused accumulation of cerebrospinal fluid in the lateral ventricles and the subarachnoid space

  5. Mycobacterium avium infection induces H-ferritin expression in mouse primary macrophages by activating Toll-like receptor 2.

  6. 3-Hydroxybutyrate dehydrogenase (show BDH1 Proteins)-2 and ferritin-H (show FTMT Proteins) synergistically regulate intracellular iron.

  7. Fth plays a critical protective role during acute kidney injury.

  8. FtH provides metabolic adaptation to tissue Fe overload, conferring tolerance to malaria

  9. The delivery of iron to oligodendrocytes via H-ferritin is a biologically relevant delivery system, given that ferritin (show FTL Proteins)--not transferrin (show Tf Proteins)--receptors can be demonstrated on oligodendrocytes in vivo.

  10. HFt taken up by TIM-2 (show TIMD2 Proteins) positive cells transited through the endosome and eventually entered a lysosomal compartment, distinguishing the HFt pathway from that of transferrin (show Tf Proteins)

Human Ferritin, Heavy Polypeptide 1 (FTH1) interaction partners

  1. Ferritin light chain (show FTL Proteins) and ferritin heavy chain are required for the neural differentiation of bone marrow-derived mesenchymal stem cells under extremely low-frequency electromagnetic field.

  2. Human FTH1 is a general pro-survival sequence.

  3. H-ferritin tissue expression and the number of CD68 (show CD68 Proteins)+/H-ferritin+ cells were increased in the lymph nodes of adult-onset Still's disease patients, and these results correlated significantly with disease severity

  4. Studies indicate that the the best characterized cytosolic ferritins in mammals are encoded by two genes, FTH and FTL (show FTL Proteins), with four exons and similar structures.

  5. high cytoplasmic FTH1 was associated with favorable prognosis whereas nuclear FTH1 staining was associated with adverse prognosis in triple negative breast cancer

  6. The goals of this study were to evaluate the multilineage differentiation ability of human mesenchymal stem cells expressing an MRI (show C7ORF49 Proteins) reporter, human ferritin heavy chain (FTH).

  7. Data suggest that iron-independent effects of ferritin (show FTL Proteins) in myeloma should be prospectively investigated in preclinical and clinical studies.

  8. Significant differences were seen in the levels of serum iron and hepcidin (show HAMP Proteins) but not ferritin (show FTL Proteins) between the -582A>G hepcidin (show HAMP Proteins) polymorphism genotypes.

  9. High ferritin (show FTL Proteins) expression is associated with malignant phenotype of breast cancer.

  10. High serum ferritin (show FTL Proteins) levels are associated with pancreatic cancer.

Cow (Bovine) Ferritin, Heavy Polypeptide 1 (FTH1) interaction partners

  1. ferritin heavy chain up-regulation may be mediated by activation of NF-kappaB (show NFKB1 Proteins) and that in turn this may be related to the resistance of bovine papillomavirus type-2 (BPV-2) infected urothelial cells to apoptosis.

Ferritin, Heavy Polypeptide 1 (FTH1) Protein Profile

Protein Summary

This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

Gene names and symbols associated with FTH1

  • ferritin, heavy polypeptide 1a (fth1a)
  • ferritin, heavy polypeptide 1 (fth1-b)
  • ferritin, heavy polypeptide 1 (fth1)
  • ferritin, heavy polypeptide 1 (FTH1)
  • ferretin 1 (FER1)
  • ferritin heavy chain (ftnA)
  • ferritin, heavy polypeptide 1-like (LOC100051036)
  • ferritin heavy chain 1 (Fth1)
  • ferritin, heavy polypeptide 1 (Fth1)
  • predicted gene 5635 (Gm5635)
  • similar to Ferritin heavy chain (Ferritin H subunit) (Proliferation-inducing gene 15 protein) (LOC681066)
  • apoferritin protein
  • ARABIDOPSIS THALIANA FERRETIN 1 protein
  • ATFER1 protein
  • EG434729 protein
  • fb06g09 protein
  • ferretin 1 protein
  • FHC protein
  • Fth protein
  • fth1 protein
  • fth1b protein
  • FTHL6 protein
  • Fthl17L5 protein
  • HFt protein
  • hm:zeh1145 protein
  • MFH protein
  • PIG15 protein
  • PLIF protein
  • wu:fb06g09 protein
  • wu:fq18c10 protein
  • zeh1145 protein

Protein level used designations for FTH1

ferritin heavy chain , ferritin, heavy polypeptide 1 , ferritin H subunit B , ferritin heavy chain 1 , ferritin heavy chain B , ferritin, heavy polypeptide 1 b , ferritin H chain , ferritin H subunit , H-ferritin , Ferritin H subunit , apoferritin , cell proliferation-inducing gene 15 protein , placenta immunoregulatory factor , proliferation-inducing protein 15 , ferritin heavy-chain , Ferritin subunit H , ferritin heavy polypeptide 1 , ferritin, heavy polypeptide-like 17 like 5

GENE ID SPECIES
58108 Danio rerio
379267 Xenopus laevis
394604 Xenopus (Silurana) tropicalis
574118 Macaca mulatta
738986 Pan troglodytes
831720 Arabidopsis thaliana
8914796 Erwinia amylovora CFBP1430
100051036 Equus caballus
100173063 Pongo abelii
100379547 Cavia porcellus
100499480 Canis lupus familiaris
14319 Mus musculus
100689102 Cricetulus griseus
2495 Homo sapiens
395970 Gallus gallus
403631 Canis lupus familiaris
397030 Sus scrofa
100009597 Oryctolagus cuniculus
25319 Rattus norvegicus
281173 Bos taurus
654516 Felis catus
100062811 Equus caballus
443355 Ovis aries
434729 Mus musculus
681066 Rattus norvegicus
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