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Ferritin, Light Polypeptide Proteins (FTL)

FTL encodes the light subunit of the ferritin protein. Additionally we are shipping FTL Antibodies (141) and FTL Kits (45) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FTL 14325  
FTL 2512 P02792
Rat FTL FTL 29292 P02793
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Top FTL Proteins at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Cow His tag 100 μg Log in to see 11 to 13 Days
$880.00
Details
HOST_Escherichia coli (E. coli) Horse His tag 100 μg Log in to see 11 to 13 Days
$915.20
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$1,998.33
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,106.50
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,405.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,405.33
Details

FTL Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
Human , ,
,

Top referenced FTL Proteins

  1. Human FTL Protein expressed in Escherichia coli (E. coli) - ABIN667723 : Baraibar, Barbeito, Muhoberac, Vidal: Iron-mediated aggregation and a localized structural change characterize ferritin from a mutant light chain polypeptide that causes neurodegeneration. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for ABIN667723

  2. Human FTL Protein expressed in Escherichia coli (E. coli) - ABIN2005241 : Munro, Aziz, Leibold, Murray, Rogers, Vass, White: The ferritin genes: structure, expression, and regulation. in Annals of the New York Academy of Sciences 1988 (PubMed)

More Proteins for Ferritin, Light Polypeptide (FTL) Interaction Partners

Mouse (Murine) Ferritin, Light Polypeptide (FTL) interaction partners

  1. Analysis of Ftl-/- mice revealed systemic and brain iron dyshomeostasis, without any noticeable signs of neurodegeneration.

  2. Noncoding G-to-T transversion (c.-168G>T) located in the iron response element (IRE) of the gene coding for ferritin light chain (FTL) cosegregated with cataract in the family.

Xenopus laevis Ferritin, Light Polypeptide (FTL) interaction partners

  1. Ferritin H subunit (show FTH1 Proteins) gene is specifically expressed in melanophore precursor-derived white pigment cells

Human Ferritin, Light Polypeptide (FTL) interaction partners

  1. Ferritin light chain and ferritin heavy chain (show FTH1 Proteins) are required for the neural differentiation of bone marrow-derived mesenchymal stem cells under extremely low-frequency electromagnetic field.

  2. This study demostrated that FTL mutation progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits show

  3. FTL expression was higher in glioblastoma than in low-grade glioma, and decreased expression of FTL correlated with increased survival in glioblastoma patients.

  4. FTL gene mutation and persistent hyperferritinemia without iron deficiency anemia after phlebotomy

  5. Ferritin plasma levels increased significantly following stem cell transplantation in graft rejection patients.

  6. Studies indicate that the the best characterized cytosolic ferritins in mammals are encoded by two genes, FTH (show FTH1 Proteins) and FTL, with four exons and similar structures.

  7. Single nucleotide polymorphisms in HAMP (show HAMP Proteins), BMP2 (show BMP2 Proteins), FTL and SLC40A1 (show SLC40A1 Proteins) genes have phenotype-modifying roles in hereditary hemochromatosis (show HFE Proteins) type 1.

  8. Genome-wide association study identifies variants in PMS1 (show PMS1 Proteins) associated with serum ferritin in a Chinese population.

  9. Data suggest that iron-independent effects of ferritin in myeloma should be prospectively investigated in preclinical and clinical studies.

  10. Urine ferritin levels are elevated significantly in systemic lupus erythematosus and correlate with disease activity.

Horse (Equine) Ferritin, Light Polypeptide (FTL) interaction partners

  1. Transmission electron microscopy shows a clear selectivity of alkylated ferritin adsorption onto the PCL (show PKD2L1 Proteins) phase while wild ferritin predominantly adsorbs onto the PDTD phase.

FTL Protein Profile

Protein Summary

This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.

Gene names and symbols associated with FTL

  • ferritin, light polypeptide (FTL)
  • ferritin light chain 1 (Ftl1)
  • ferritin, heavy polypeptide 1 (fth1-a)
  • ferritin light-chain (CpipJ_CPIJ004069)
  • ferritin light chain 1 (Ftl)
  • ferritin light chain 2 (Ftl2)
  • ferritin, light polypeptide (Ftl)
  • ferritin, light polypeptide (LOC100349769)
  • apoferritin protein
  • ferritin protein
  • fhc protein
  • FT protein
  • FTD protein
  • fth protein
  • fth1 protein
  • fthl6 protein
  • Ftl protein
  • Ftl-1 protein
  • Ftl-2 protein
  • Ftl1 protein
  • FTL2 protein
  • ftn-2 protein
  • L-ferritin protein
  • NBIA3 protein
  • pig15 protein
  • plif protein

Protein level used designations for FTL

ferritin, light polypeptide , ferritin L subunit 1 , XL2-17 , ferritin H subunit A , ferritin heavy chain 2 , ferritin heavy chain A , ferritin light-chain , ferritin L subunit , ferritin light chain , ferritin L-chain , ferritin light polypeptide-like 3 , ferritin light chain 2 , ferritin light chain 1 , ferritoid

GENE ID SPECIES
723530 Macaca mulatta
14325 Mus musculus
399281 Xenopus laevis
6035538 Culex quinquefasciatus
100173858 Pongo abelii
100379558 Cavia porcellus
14337 Mus musculus
2512 Homo sapiens
477042 Canis lupus familiaris
397035 Sus scrofa
286861 Bos taurus
100009254 Oryctolagus cuniculus
29292 Rattus norvegicus
100349769 Oryctolagus cuniculus
654515 Felis catus
100051593 Equus caballus
101103834 Ovis aries
378899 Gallus gallus
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